• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    An apparatus and method for measuring the linear extent and hence the concentration of several constituent blood cell types which are contained in the buffy coat of a centrifuged sample of anticoagulated blood.
    公开号:SU940656A3
    申请号:SU782605501
    申请日:1978-04-17
    公开日:1982-06-30
    发明作者:Кларк Вордлоу Стефен
    申请人:За витель Стефен Кларк Вордлоу；
    IPC主号:
    专利说明:

    The invention relates to medicine, a technique, namely, devices for hematological studies.
    A device for counting blood cells, which 5 contains a separation chamber installed with the possibility of rotation around a fixed axis [1].
    However, the known device does not provide the necessary accuracy of calculation, which complicates the diagnosis of the disease.
    The purpose of the invention is to increase the accuracy of the calculation.
    This goal is achieved by the fact that the device for counting blood cells, containing a separation chamber mounted for rotation around a fixed axis, is equipped with a device 2 about to accommodate a separation chamber, focusing and sighting optical systems, control units and information processing with a digital indicator and capillary the tube.
    A device for accommodating the separation chamber is installed with the possibility of moving along the axis of the camera and is connected to the information processing unit through a linear displacement transducer into an electric signal. .
    The focusing optical system contains a light source and a light filter, and the sighting optical system consists of a light filter, an eyepiece and a reference line placed in the focal plane of the eyepiece.
    In FIG. 1 shows a device for counting shaped elements, in a perspective view; in FIG. 2 - optical-kinematic diagram of the device.
    The device comprises a separation chamber in the form of a capillary tube • 1, mounted for rotation around a fixed axis using an electric motor 2 with a chuck 3, in which the tube 1 is placed at one end. The opposite end of the tube 1 is rotatable in a rack 4, which together with the electric motor 2, devices for accommodating the separation chamber are mounted on the platform 5. The platform 5 is mounted on the base 6 with the possibility of moving along the axis of the tube 1 using the screw 7 installed about in the threaded hole 8 of the base 6. In addition, a gear 9 is mounted on the screw 7, interacting with the gear 10, 10 on the shaft 11 of which a potentiometer 12 of the converter for linearly moving the separation chamber into an electrical signal is installed. In this case, the platform 5 is placed on the base 6 between the end face 13 of the screw 7 and the spring 14, fixed at one end to the stop 15 of the base 6.
    In addition, the device contains> a focusing optical system, 2 q including a light source 16, a capacitor 17 and a filter 18, as well as a viewing optical system consisting of an eyepiece 19, a reference line 20, a filter 21 and a lens 22. 2 5
    Moreover, the reference line 20 is placed in the focal plane of the eyepiece 19 · A converter for linearly moving the separation chamber into an electrical signal is connected to an information processing unit 30 (not shown) equipped with a digital indicator 23. In addition, the device is equipped with a control unit (not shown).
    The device works as follows - 35 times.
    The capillary tube 1 with the centrifuged blood sample which is divided into separate layers, is placed in the apparatus and zakrep- lyayut 40 in the chuck 3 · Include a focusing optical system which illuminates the capillary tube 1 and observing through an optical system VIZIR boundary separating adjacent layers of the sample blood in the tube 1, produce the combination of the above boundaries with the reference line of the sighting system.
    In this case, to combine the separation boundary between the layers and the reference line, rotate the screw 7, which moves the platform 5 in the direction along the axis of the tube 1. At the same time, the screw 7 rotates the axis of the potentiometer 12 through the gears 9 and 10 and the shaft 11, setting it to the position where the initial reading the length of the measured layer. With this position 4 of the potentiometer 12, its analog electrical signal is converted by the information processing unit into a digital signal with a zero value, which is reproduced on the indicator 23.
    Then, rotating the screw, 7 move the capillary ‘tube 1 until the reference line coincides with the other boundary of the measured layer. In this position, the electric signal of the potentiometer 12 is converted by the information processing unit into a digital signal with a final value of the number of formed elements of the blood sample in the measured layer. The digital signal is reproduced ί on the indicator 23When performing the above measurements, the capillary tube 1 is rotated using an electric motor 2, which ensures optical alignment of the layer boundary of the blood sample and increase the accuracy of measurement.
    The device provides a consistent measurement of all layers of the sample represented in the capillary tube. The processing unit allows you to calculate the number of shaped elements and reproduce the final results on a digital indicator.
    Thus, the design of the proposed device can improve the accuracy of the calculation of blood cells.
    权利要求:
    Claims (3)
    [1]
    In the rack k, which, together with the electric motor 2, is mounted on the platform 5 of the device for accommodating the separation chamber, the Platform 5 is mounted on the base 6c, possibly moving along the axis of the tube 1 with a screw 7 installed in the threaded hole 8 of the base 6. In addition, screw 7 is fixed gear 9, which interacts with gear 10, on the shaft 11 of which the potentiometer 12 of the linear displacement transducer of the separation chamber into an electrical signal is mounted. In this case, the mold 5 is placed on the base 6 between the end face 13 of the screw 7 and the spring I fixed at one end to the stop 15 of the base 6. In addition to the TorOj, the device contains a focusing optical system: a switch including a light source 16, a condenser 17 and a light filter 18, as well as a sighting optical system consisting of an eyepiece 19 of the reference line 20, a light filter 21 and a lens 22, which is attached to the reference line 20 in the focal plane of the eyepiece 19. The linear displacement device of the separation chamber is electrically connected to the processing unit. deformations of (not shown) equipped with a digital indicator 23- Furthermore, the device is provided with a control unit (not shown) The device operates as follows. A capillary tube 1 with a centrifuged blood sample, which turns out to be separated into separate layers, is placed into the device and fixed in the clamping cartridge 3- The focusing optical system, which illuminates the capillary tube 1, is switched on and observed through the sighting optical system separating the adjacent layers of the blood sample in tube 1, aligning the above boundary with the reference line of the sighting system. At the same time, in order to align the separation boundary with the reference line, rotate the screw 7 which moves the platform 5 in the direction along the axis of the tube 1. At the same time, the screw 7 through gears 9 and 10 and the shaft 11 rotates the axis of the potentiometer 12, setting it to the initial counting the length of the measured layer. At this position of the potentiometer 12, its analog electrical signal is converted by the information processing unit into a digital signal with a zero value, which is reproduced on the indicator 23. Then, turning the screw 7, the capillary tube 1 is moved to align the reference line with another boundary of the layer being measured. In this position, the electric signal of potentiometer 12 is converted by the information processing unit into a digital signal with a finite value of the number of formed elements of the blood sample in the layer being measured. The digital signal is reproduced on the indicator 23. When the above measurements are taken, the capillary tube 1 is rotated by the electric motor 2, thereby ensuring optical alignment of the interface between the layers of the blood sample and improving the measurement accuracy. The device provides a consistent measurement of all sample layers presented in the capillary tube. In this case, the processing unit allows you to calculate the number of shaped elements and reproduce the final results on a digital indicator. Thus, the design of the proposed device allows to improve the accuracy of counting blood cells. Claim 1. Device for counting blood cells, containing a separation chamber mounted rotatably around a fixed axis, characterized in that, in order to improve the accuracy of the sub-. . account, it is equipped with a device for placing a separation chamber, focusing and sighting optical systems, control and information processing units with a digital indicator and a capillary tube,
    [2]
    2. The device is pa, .1, which is connected with the fact that the device for accommodating the separation chamber is installed with the possibility of moving along the axis of the camera and through the linear-to-electric converter into an electrical signal connected to the information processing unit.
    [3]
    3. The device according to claim 1, wherein the focusing optical system comprises a light source and a light filter, and the sight optical system consists of a light filter, an ocular and a reference line placed in the focal plane of the ocular.
    Sources of information taken into account in the examination
    t. Guidelines for clinical laboratory research. Ed. E. A. Kost et al., M., Medicine, 196, p. 163.
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    同族专利:
    公开号 | 公开日
    JPS53129485A|1978-11-11|
    JPS6139620B2|1986-09-04|
    FR2388277B1|1982-04-16|
    IT1102583B|1985-10-07|
    DE2816870C2|1987-04-23|
    DE2816870A1|1978-10-26|
    FR2388277A1|1978-11-17|
    GB1565492A|1980-04-23|
    US4156570A|1979-05-29|
    IT7848875D0|1978-04-12|
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    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    US05/788,509|US4156570A|1977-04-18|1977-04-18|Apparatus and method for measuring white blood cell and platelet concentrations in blood|
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