• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    A method of, and circuit for, producing measuring pulses in a particle analyzer for the analysis of particles suspended in a liquid, especially blood cells, comprising a conductivity or measuring cell, whose impedance between two terminals of the conductivity cell changes upon passage of a particle through such conductivity cell. A controllable current supply powers the conductivity cell with a current regulated to maintain a reference value corresponding to a control value. A receiver functioning as a high-pass filter and having high input impedance serves for the essentially currentless removal of a potential between the terminals of the conductivity cell and for forming a receiver signal corresponding to such components of such potential whose frequency is above a threshold or cut-off frequency corresponding to the high-pass filter. The control value is formed from the sum of a predetermined reference value and the received signal. There is formed a measuring signal proportional to the difference of the control value and the reference value and whose timewise changes correspond to the measuring pulses.
    公开号:SU733524A3
    申请号:SU782631654
    申请日:1978-06-29
    公开日:1980-05-05
    发明作者:Гуггенбюль Вальтер
    申请人:Контравес Аг (Фирма)；
    IPC主号:
    专利说明:

    rum. Others may also be used that contain semiconductor elements containing a saturation zone, for example, a bipolar transistor or also an appropriately connected optocoupler.
    The device includes a switched circuit, which includes the measuring element 9, connected via common terminal 1 to the element 7, Element 7 through the common node 10 of the circuit is connected to the limiting resistor 6.
    In addition, the device includes a receiving device 11, which contains an operational amplifier 12 with a high input impedance. The input terminal 13 of the non-inverting input of amplifier 12 is connected to terminals 1 and 3 and, thus, to the electrode of measuring element 9. Another input terminal 14 of the input of amplifier 12 that is inputting is connected through resistor 15 to output terminal 16 of amplifier 12 and through a capacitor 17, as well as the node 18 of the circuit is connected to the terminal 2, and thus to the other electrode of the measuring element 9. In addition, the node 18 of the circuit is connected to the circuit 20 of the ground through the node 19 of the circuit. Such a circuit acts as a high-pass filter. The cut-off frequency of the high-pass filter corresponds to a time constant of the series circuit of the resistor 15 to the capacitor 17. The output terminal 16 of the operational amplifier 12 is connected to the output or output terminal 21 of the receiving device 11 via a capacitor 22, while the output terminal 21 via a resistor 23, node 24 circuits and a slight internal impedance are connected to the source 25 of a stabilized reference voltage.
    The series circuit of the capacitor 22 and the resistor 23 form the second high-pass filter of the same frequency limit.
    At the output of the device, a counting unit 26 is installed, consisting of an operational amplifier 27 with an output 28, an inserting input 29, a feedback resistor 30, and an input resistor 31. Moreover, the non-inverting input of amplifier 27 is connected to the node 32 of the circuit.
    Terminal 21 is connected to control input 8 via differential amplifier 33. Terminal 21 is connected to non-inverting input 34 of differential amplifier 33, while output 35 of differential amplifier is connected to control input 8. Inverting input 36 of differential amplifier 33 through Node 32 connected to the node 10 of the chain. Non-inverting input of the operational amplifier 27 is connected to the node 32 of the circuit. .
    The device works as follows. To the node 10 of the circuit is connected the supply terminal of the toxic control element 7. As a result, a stable voltage difference is created between the node 10 of the circuit and the control input 8. The phase shifts in both high-pass filters are mainly compensated, so that at terminal 21 a signal appears that is proportional to the first time derivative of the voltage variation between terminals 3 and 4 of the measuring element 9, whose frequency spectrum lies above the limiting frequency, and The voltage source 25 of the reference voltage is superimposed on the signal present at terminal 21.
    Counting unit 26 measures this signal and at the same time it subtracts from it the voltage of the source 25 of the reference voltage. Moreover, the node 24 of the circuit serves as the input of the counting unit 26 for the subtracted voltage.
    The non-inverting input of the operational amplifier 27 is connected to the circuit node 32, which serves as the input of the counting unit 26 for the voltage component. Moreover, the voltage on node 32 is basically equal to the voltage on terminal 21, the voltage difference on the line between terminal 2 and node 24 is amplified by an operational amplifier 27, which also serves as the output of counting unit 26. The output signal is proportional to the voltage difference across terminal 21 and node 24, the proportionality coefficient being determined by the magnitude of resistors 30 and 31. The signal at output 28 of counting unit 26 is measuring pulses that are further processed. It should be noted that the connection of the output terminal of the receiving device 11 to the input of the counting unit 26 is performed by a low-pass filter: the combination of the resistor 23 and the low internal impedance of the voltage source 25 acts exactly like an RC low-pass filter, so that only a constant voltage source voltage reference.
    Differential amplifier 33 operates in such a way that the voltage difference at its inputs is still negligible. The voltage between knotsm 32 and terminal 21, therefore, is basically equal to the value occurring by 21. The counting unit 26 here forms (at terminal 21) the difference between the actual signal value and the reference value. As a result of the fact that the value of the processing
    权利要求:
    Claims (3)
    [1]
    Claim
    1. A device for generating measuring pulses in particle analyzers in liquids, containing a measuring element with two electrodes, a controlled power supply, a receiving device with an amplifier and a high-pass filter, characterized in that, in order to increase noise immunity during the formation of measuring pulses, it is introduced the counting unit is a differential amplifier and a reference voltage source, the output of which is connected to the inputs of the counting unit and the differential amplifier through additionally introduced resistors.
    [2]
    2. The device according to claim 1, with the fact that the controllable power supply is made in the form of a stable voltage source connected in series with a limiting resistor and a current-determining element, made mainly in the form of a field-effect transistor, the control input of which is connected to differential amplifier output.
    [3]
    3. The device according to claims 1, 2, characterized in that the limiting resistor of the controlled power supply is connected to a counting unit and a differential amplifier, and the output of the receiver is connected to the second input of the differential amplifier through a transition capacitor.
    类似技术:
    公开号 | 公开日 | 专利标题
    US5113143A|1992-05-12|Chopper amplifier for measuring low DC current
    SU733524A3|1980-05-05|Measuring pulse former for analyzers of particles in liquid
    KR850000772B1|1985-05-29|Differential amplifier having a lowpass characteristic
    US5793243A|1998-08-11|Method of stabilizing an electronic signal integrator
    CA1132208A|1982-09-21|Oscillator having low noise signal extractioncircuit
    US4523109A|1985-06-11|Differential amplifier filter circuit having equal RC products in the feedback and output loops
    KR880014746A|1988-12-24|Temperature Stabilized RF Detector
    RU2024885C1|1994-12-15|Device for measuring conductance
    Wei et al.1992|CMOS chopper amplifier for chemical sensor
    US5920232A|1999-07-06|Compensated, bias-dependent signal filter and amplifier circuit
    SU1156031A1|1985-05-15|D.c.voltage stabilizer
    JPS60231178A|1985-11-16|Impedance measuring appratus
    SU1190305A1|1985-11-07|Conductivity apparatus
    Collins et al.1973|``Boxcar''Attachment for Oscilloscopes Useful for Low Level Signals
    SU1695482A1|1991-11-30|Parametric speed stabilizer
    SU943675A1|1982-07-15|Controlled dc voltage source
    SU1190319A1|1985-11-07|Apparatus for measuring magnetic susceptibility
    SU1739480A1|1992-06-07|Negative inductance simulator
    SU1599674A1|1990-10-15|Device for measuring temperature
    SU1576869A1|1990-07-07|Apparatus for measuring resistances
    RU2034331C1|1995-04-30|Integrator with long duration of integration
    SU1051511A1|1983-10-30|Periodic signal stabilizer
    SU1181406A1|1986-02-23|Amplifier with zero level stabilization
    KR100218396B1|1999-09-01|Guarding circuit for in-circuit tester
    SU572699A1|1977-09-15|Coulometric titration apparatus
    同族专利:
    公开号 | 公开日
    DE2824852B2|1979-12-13|
    JPS5446092A|1979-04-11|
    FR2401417A1|1979-03-23|
    DE2824852C3|1980-08-21|
    BE868040A|1978-10-02|
    GB2003279B|1982-03-03|
    DE2824852A1|1979-03-08|
    SE7808120L|1979-02-26|
    IT1098137B|1985-09-07|
    NL7808723A|1979-02-27|
    IT7826915D0|1978-08-22|
    CH618514A5|1980-07-31|
    GB2003279A|1979-03-07|
    DK342578A|1979-02-26|
    US4277743A|1981-07-07|
    ES471838A1|1979-02-01|
    CA1102878A|1981-06-09|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US3993948A|1969-12-15|1976-11-23|Coulter Electronics, Inc.|Particle analyzer having scanning apparatus series coupled between a d.c. power source and the parallel connection of a d.c. short-circuiting device and a voltage sensitive signal detector|
    US3706030A|1970-12-28|1972-12-12|Coulter Electronics|Electronic particle detector of the coulter type having conductivity change independence circuitry|
    US3924180A|1973-10-12|1975-12-02|Us Energy|Potential sensing cell analyzer|
    US4093849A|1976-04-28|1978-06-06|J. T. Baker Chemical Co.|Automatic blood analyzing system|JPS5846149U|1981-09-25|1983-03-28|
    JPH01112448U|1988-01-21|1989-07-28|
    DE19728031A1|1997-07-01|1999-01-07|Bernd Horst Dr Meier|Moving liquid flow and volume measuring method|
    JP3611771B2|2000-04-21|2005-01-19|シスメックス株式会社|Particle signal processing apparatus and particle measuring apparatus using the same|
    JP4999242B2|2001-09-06|2012-08-15|シスメックス株式会社|Resistive blood cell counter|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    CH1039077A|CH618514A5|1977-08-25|1977-08-25|
    [返回顶部]