• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    1. Water-miscible solutions of 1-[3-methyl-4-(4'-trifluoromethyl- -thiophenoxy)-phenyl]-3-methyl-1,3,5-triazine-2,4,6-(1- H, 3H, 5H)-trione, characterized in that they contain one or more polar solvents and have an alkaline reaction.
    公开号:SU1276249A3
    申请号:SU843688287
    申请日:1984-01-09
    公开日:1986-12-07
    发明作者:Феге Герберт
    申请人:Байер Аг (Фирма)；
    IPC主号:
    专利说明:

    312762494
    so that, in order to increase lenglikol with the addition of the carbonystability of the drug, the mixing of sodium or polyethylene glycol is carried out at 60-120 ° C with a molecular weight of 400 s dinn to 9.8-9.9 using DL - lysine in the form of osania as a solvent for propionation.
    权利要求:
    Claims (2)
    [1]
    1. The method of obtaining a water-miscible preparation of 1- [3-methyl-4 (4-trifluoromethylthiophenoxy) phenyl] 3-methyl-1,3,5-triazine-2,4,6- (1H, 3H, 5H) - Trion, including mixing it with a polar water-miscible solvent, characterized in that, in order to increase the stability of the preparation, the mixing is carried out at 60-120 ° C, bringing the mixture to pH 8-11 by using triethanolamine or monoethanolamine as a solvent, or mixtures of triethanolamine with lactic acid or mixtures of monoethanolamine with N-methylpyrrolidone.
    [2]
    2. A method of obtaining a water-miscible preparation of 1- [3-methyl-4 (4 · trif> tormethylthiophenoxy) phenyl] 3-methyl-1,3,5-triazine-2,4,6- (1H, ZN, 5H) -trione, including mixing it with a polar water-miscible solvent, distinguishing 3
    1276249 4 with the fact that, in order to increase the stability of the drug, mixing is carried out at 60-120 ° C to bring the mixture to pH 9.8-9.9 by using propylene glycol as a solvent with the addition of sodium carbonite or polyethylene glycol with molecular mass of 400 with the addition of DL - lysine in the form of a base.
    • Compiled by I. Belousov
    类似技术:
    公开号 | 公开日 | 专利标题
    SU1276249A3|1986-12-07|Method of producing water-miscible preparation of 1-/3-methyl-4-|-phenyl/3-methyl-1,3,5,-triazine-2,4,6-|-trion
    JPS6079012A|1985-05-04|Production of water-soluble dicarboxylic acid imide compound
    IE42979L|1976-10-21|Pyrazinyl piperazine derivatives
    JPS58219114A|1983-12-20|Hypotensive agent
    JPS565056A|1981-01-20|Feed additive for cultured aquatic life
    JPS52109545A|1977-09-13|Preparation of aqueous polyolefin dispersions
    JPH03240793A|1991-10-28|Purification of amphotericin b and its composition
    KR870006059A|1987-07-09|6H-isoxazolo [5,4-d] pyrazolo [3,4-b] pyridine and preparation method thereof
    IE33065L|1969-10-26|Camphoryl sulphonyl urea derivatives
    JPS53147044A|1978-12-21|Guanidinobenzoic acid derivative and its preparation
    JPS5296721A|1977-08-13|Stable pharmaceutical dispersion
    JPS5321186A|1978-02-27|Penicillanic acid derivatives and their preparation
    JPS5212145A|1977-01-29|Improved process for preparation of aromatic sulfonic acid alkali salt
    JPS61251770A|1986-11-08|Anticoagulant
    JPS53149985A|1978-12-27|Preparation of 5-fluorouracil derivatives
    JPH02204489A|1990-08-14|Readily soluble 2',3'-dideoxyinosine, production thereof and production of aqueous solution of 2',3'-dideoxyinosine
    JPS5346950A|1978-04-27|1-acetylaminotricyclo|undecane and its preparation
    JPS58105917A|1983-06-24|Solution of isosorbide nitrate
    JPS60158138A|1985-08-19|Preparation of disodium dl-malate hudrate
    JPS5353698A|1978-05-16|Pyrrolotriazolopyrimidine derivatives and their preparation
    JPS5223098A|1977-02-21|Preparation of pyridocarbazoles
    JPS5233661A|1977-03-14|Process for preparation of 2-naphthol-3,6_disulfonic acid salts
    JPS63190868A|1988-08-08|Optically active sulfonyloxy compound and production of optically active amine using said compound
    JPS5566945A|1980-05-20|Preparation of aqueous suspension of phenol-formaldehyde
    JPH01250383A|1989-10-05|Benzothiepino|pyridazine compound
    同族专利:
    公开号 | 公开日
    IL70641D0|1984-04-30|
    FI840082A0|1984-01-10|
    DK165668B|1993-01-04|
    PT77916A|1984-02-01|
    FI81961C|1991-01-10|
    JPS59139316A|1984-08-10|
    IE840047L|1984-07-12|
    FI840082A|1984-07-13|
    IE56522B1|1991-08-28|
    IL70641A|1987-01-30|
    PT77916B|1986-04-16|
    DK12184D0|1984-01-11|
    JPH0216730B2|1990-04-18|
    EP0116175A3|1986-02-19|
    DK12184A|1984-07-13|
    HU192529B|1987-06-29|
    FI81961B|1990-09-28|
    MY101193A|1991-07-31|
    DE3300793A1|1984-07-12|
    AU2317284A|1984-07-19|
    ZA84219B|1984-09-26|
    KR900007310B1|1990-10-08|
    DE3379195D1|1989-03-23|
    EP0116175B1|1989-02-15|
    KR840007355A|1984-12-07|
    ES8500058A1|1984-10-01|
    AT40792T|1989-03-15|
    AU561923B2|1987-05-21|
    CS235997B2|1985-05-15|
    PH20973A|1987-06-15|
    ES528805A0|1984-10-01|
    EP0116175A2|1984-08-22|
    DK165668C|1993-06-01|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    FR1476867A|1966-03-04|1967-04-14|Wellcome Found|Preparation of stable aqueous solutions containing a mixture of sulfaquinoxaline and diaveridine|
    DE2718799C2|1977-04-27|1989-02-23|Bayer Ag, 5090 Leverkusen, De|
    EP0081142B1|1981-12-03|1986-06-25|BASF Aktiengesellschaft|1,3,5-triazinones, process for their preparation and their use in combating undesired plant growth|DE3408768A1|1984-03-09|1985-09-12|Bayer Ag, 5090 Leverkusen|IMMUNTIMULATING AGENTS|
    DE3703103A1|1987-02-03|1988-08-11|Bayer Ag|AGENT AGAINST FISH PARSITES|
    DE3703105A1|1987-02-03|1988-08-11|Bayer Ag|MEDICINE AGAINST PROTOCOES IN INSECTS|
    DE3814323A1|1988-04-28|1989-11-09|Hoechst Ag|WATER-SOLUBLE PREPARATIONS BY COCCIDIOSTATICA|
    CZ146296A3|1995-06-02|1997-04-16|American Cyanamid Co|3--1--s-triazine-2,4,6-oxo or thiotriones, process of their preparation and herbicidal agents|
    EP0989851B1|1997-07-29|2002-10-02|PHARMACIA & UPJOHN COMPANY|Self-emulsifying formulation for acidic lipophilic compounds|
    DE19824483A1|1998-06-02|1999-12-09|Bayer Ag|Semi-solid aqueous preparations for oral application of toltrazuril sulfone|
    DE102007025908A1|2007-06-01|2008-12-04|Bayer Healthcare Ag|Formulations containing triazinones and iron|
    DE102009012423A1|2009-03-10|2010-09-16|Bayer Animal Health Gmbh|Preparation based on oil|
    EP2740470A1|2012-12-07|2014-06-11|Ceva Sante Animale|Treatment of Coccidiosis with intramuscular triazine composition|
    EP2740469A1|2012-12-07|2014-06-11|Ceva Sante Animale|New treatments with triazines|
    EP2740492A1|2012-12-07|2014-06-11|Ceva Sante Animale|Triazine formulations with a second active ingredient and surfactant|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    DE19833300793|DE3300793A1|1983-01-12|1983-01-12|Coccidiosis|
    [返回顶部]