专利摘要:
There are provided stable concentrated solutions of cisplatin in a solvent comprising polyethylene glycol or methoxy polyethylene glycol, or a mixture thereof, plus water and a nontoxic pharmaceutically acceptable source of chloride ion.
公开号:SU1056893A3
申请号:SU813265697
申请日:1981-03-30
公开日:1983-11-23
发明作者:Артур Каплан Мюррэй;Питер Гранатек Альфонс
申请人:Бристоль-Мейерз Компани (Фирма);
IPC主号:
专利说明:

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权利要求:
Claims (1)
[1]
* METHOD FOR PRODUCING A CISPLATIN SOLUTION by introducing cisplatin into an aqueous solution containing a pharmaceutically non-toxic source of chloridion, characterized in that, in order to ensure the possibility of obtaining a stable solution containing 2.5-25 mg / ml cisplatin, polyethylene glycol is preliminarily added to the aqueous solution, having a molecular weight of 150-9000 or methoxypolyethylene glycol, having a molecular weight of 300-6000, in the number of st. ve 30-95% of the volume of the solution.
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引用文献:
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US4177263A|1972-02-28|1979-12-04|Research Corporation|Anti-animal tumor method|
SE445172B|1978-05-30|1986-06-09|Bristol Myers Co|STABLE, STERILE WATER DISPOSAL OF CISPLATIN IN UNIT DOSAGE FORM|IT1153974B|1982-09-23|1987-01-21|Erba Farmitalia|PHARMACOLOGICAL COMPOSITIONS BASED ON CISPLATIN AND METHOD FOR THEIR OBTAINMENT|
NL8303657A|1983-10-24|1985-05-17|Pharmachemie Bv|SOLUTION, STABLE, AQUEOUS, AQUEOUS, CONTAINING SOLUTION OF CISPLATINE, AND METHOD OF PREPARING THEREOF.|
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JP4445304B2|2004-03-26|2010-04-07|オンキヨー株式会社|Switching amplifier|
US8852566B2|2009-03-26|2014-10-07|Warsaw Orthopedic, Inc.|Compositions and methods for preferential distribution of active agents to injury sites|
法律状态:
优先权:
申请号 | 申请日 | 专利标题
US13537380A| true| 1980-03-31|1980-03-31|
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