• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The patent discloses a fully automatic enzyme immunoassay and luminescence dual-system analyzer, including a housing and a workbench; a suction head rack, a sample and reagent rack, a needle removal rack, a vibration incubating device, a plate washer and a luminescence instrument are provided on the workbench according to a placement sequence; cover plate racks are arranged on an external workbench of the vibration incubating device; and an ELIASA is arranged on an internal workbench of the vibration incubating device. The patent has the following beneficial effects: the fully automatic enzyme immunoassay and luminescence dual-system analyzer adopts a modular design and is integrated with sample adding, incubation and plate washing, so the analytical speed is quick, and the working efficiency is high. Functions of an enzyme immunoassay analyzer and a chemiluminescence analyzer are integrated, so enzyme immunoassay analysis and chemical analysis may be performed individually or simultaneously, and therefore, requirements on medical analysis in actual use are met.
    公开号:NL2023060A
    申请号:NL2023060
    申请日:2019-05-02
    公开日:2019-05-22
    发明作者:Zhang Lihai；Shao Wei；Lin Ping
    申请人:Yantai Addcare Biotech Co Ltd；
    IPC主号:
    专利说明:

    FULLY AUTOMATIC ENZYME IMMUNOASSAY AND LUMINESCENCE DUALSYSTEM ANALYZER
    FIELD
    The patent relates to a fully automatic enzyme immunoassay and luminescence dual-system analyzer, and belongs to the field of medical appliances.
    BACKGROUND
    An enzyme immunoassay experiment and a chemiluminescence experiment are basic and conventional detection technologies for modern medicine clinical examination, and may be applied to detection in aspects of prenatal and postnatal cares, tumor markers, thyroids, autoimmunity, sex gland hormones, steroids, infectious diseases, growth defects, myocardial markers, anaphylaxis and anemia, renal functions, glucose metabolism, bones/minerals and microbiology, etc.
    With so huge detection functions, a detection unit such as a hospital can hardly do without the help of an enzyme immunoassay analyzer and a chemiluminescence analyzer. With a view to the long-term use, it is very necessary to improve the analytical speed and accuracy of an analytical device. By combining the enzyme immunoassay experiment and the chemiluminescence experiment into one analyzer, the analysis time can be greatly shortened, and the analysis efficiency is improved.
    GENERAL STATEMENTS
    In view of the shortages in the prior art, the patent provides a fully automatic enzyme immunoassay and luminescence dual-system analyzer, so as to solve the problems of low experimental speed, low work efficiency and low accuracy of existing enzyme immunoassay analyzer and chemiluminescence analyzer.
    The technical solutions of the patent to solve the above technical problems are as follows: a fully automatic enzyme immunoassay and luminescence dual-system analyzer includes a housing and a workbench; a suction head rack, a sample and reagent rack, a needle removal rack, a vibration incubating device, a plate washer and a luminescence instrument are provided on the workbench according to a placement sequence; cover plate racks are arranged on an external workbench of the vibration incubating device; and an eliasa is arranged on an internal workbench of the vibration incubating device.
    The patent has the following beneficial effects: the fully automatic enzyme immunoassay and luminescence dual-system analyzer adopts a modular design and is integrated with sample adding, incubation and plate washing, so the analytical speed is fast and the working efficiency is high. Functions of the enzyme immunoassay analyzer and the chemiluminescence analyzer are integrated, so enzyme immunoassay analysis and chemical analysis may be performed individually or simultaneously; and therefore, requirements on medical analysis in actual use are met.
    On the basis of the above technical solutions, the patent may further make the following improvements.
    Further, an X-direction guide track is arranged on a long-edge direction of the housing; a Y-direction guide track is arranged on the X-direction guide track; a sample adding device and a manipulator device are arranged at two sides of the Y-direction guide track; the sample adding device includes a moving arm and a sample adding needle; the moving arm is mounted on the Y-direction guide track; the sample adding needle is arranged at a lower end of the moving arm; the manipulator device includes a manipulator seat and a manipulator; the manipulator seat is mounted on the Y-direction guide track; and the manipulator is arranged at a lower end of the manipulator seat.
    Further, a needle entering groove is formed on an upper top surface of the needle removal rack; the size of the needle entering groove is greater than the maximum diameter of a suction head; a needle clamping hole is formed at an edge of the needle entering groove; and the size of the needle clamping hole is smaller than the maximum diameter of the suction head.
    Further, a luminescence instrument plate putting place is arranged inside the luminescence instrument; and the luminescence instrument can be pushed out or pulled back at the luminescence instrument plate putting place.
    Further, an eliasa plate putting place is arranged inside the eliasa; and the eliasa can be pushed out or pulled back at the eliasa plate putting place.
    The luminescence instalment plate putting place can be mounted in the luminescence instrument via a synchronous belt transmission device, a lead screw transmission device or a gear-rack transmission device; the eliasa plate putting place can be mounted in the eliasa via a synchronous belt transmission device, a lead screw transmission device or a gear-rack transmission device; and the transmission devices drive the luminescence instrument plate putting place or the eliasa plate putting place to be pushed out or pulled back.
    BRIEF DESCRIPTION OF THE DRAWINGS
    Features and advantages of some embodiments of the present invention, and the manner in which the same are accomplished, will become more readily apparent upon consideration of the following detailed description of the invention taken in conjunction with the accompanying drawings, which illustrate preferred and exemplary embodiments and which are not necessarily drawn to scale, wherein: FIG. 1 is a top view of the patent. FIG. 2 is a stereoscopic diagram of the patent. FIG. 3 is a structural schematic diagram of a Y-direction guide track, a sample adding device and a manipulator device. FIG. 4 is a structural schematic diagram of a needle removal rack.
    References in the figures: 1-housing; 2-workbench; 3-suction head rack; 4-sample and reagent rack; 5-needle removal rack; 6-vibration incubating device; 7-plate washer; 8-luminescence instalment; 9-luminescence instalment plate putting place; 10-eliasa; 11-eliasa plate putting place; 12-X-direction guide track; 13-Y-direction guide track; 14-moving arm; 15-sample adding needle; 16-needle entering groove; 17-needle clamping hole; 18-manipulator seat; 19-manipulator; 20-cover plate rack.
    DETAILED DESCRIPTION
    The principles and characteristics of the patent will be described below with reference to accompanying drawings. The examples described here are merely to explain the patent and are not intended to limit a scope of the patent.
    As shown in FIG. 1 and FIG. 2, a fully automatic enzyme immunoassay and luminescence dual-system analyzer includes a housing 1 and a workbench 2; a suction head rack 3, a sample and reagent rack 4, a needle removal rack 5, a vibration incubating device 6, a plate washer 7 and a luminescence instrument 8 are provided on the workbench 2 according to a placement sequence; a luminescence instalment plate putting place 9 is arranged inside the luminescence instrument 8; the luminescence instrument 8 can be pushed out or pulled back at the luminescence instrument plate putting place 9; cover plate racks 20 are aaanged on an external workbench 2 of the vibration incubating device 6; an eliasa 10 is arranged on an internal workbench 2 of the vibration incubating device 6; an eliasa plate putting place 11 is arranged inside the eliasa 10; the eliasa plate putting place 11 is configured to place a microplate; the sample and reagent rack 4 is divided into a sample rack and a reagent rack for respectively placing samples and reagents; multiple cover plate racks 20 are provided and are arranged at positions corresponding to each of incubation positions; cover plates are placed on the cover plate racks 20; and the cover plates are configured to perform heat preservation on the incubation positions.
    An X-direction guide track 12 is arranged on an upper housing 1 of the workbench 2; a Y-direction guide track 13 is arranged on the X-direction guide track 12; one side of the Y-direction guide track 13 is provided with a sample adding device, and the other side of the Y-direction guide track 13 is provided with a manipulator device; and the operations of the two devices are independent to each other.
    The sample adding device includes a moving arm 14 and a sample adding needle 15; the moving arm 14 is mounted on the Y-direction guide track 13; a needle entering groove 16 is formed on an upper top surface of the needle removal rack 5; the size of the needle entering groove 16 is greater than the maximum diameter of a suction head; a needle clamping hole 17 is formed at an edge of the needle entering groove 16; and the size of the needle clamping hole 17 is smaller than the maximum diameter of the suction head. Referring to FIG. 3, the moving arm 14 is first moved to the suction head rack 3 to mount the suction head and then add the sample and the reagent to the microplate; and after the sample is added completely, the moving arm 14 is moved to the needle removal rack 5 to remove a needle.
    As shown in FIG. 4, the manipulator device includes a manipulator seat 18 and a manipulator 19; the manipulator seat 18 is mounted on the Y-direction guide track 13; and the manipulator 19 is arranged at a lower end of the manipulator seat 18. Before incubation, the manipulator 19 grabs the cover plates to the incubation places; after the incubation, the microplate is transferred to the plate washer 7; and after plate washing, the microplate is transferred to the eliasa 10 or the luminescence instalment 8 for reading.
    Although the present invention has been described in connection with specific exemplary embodiments, it should be understood that various changes, substitutions, and alterations apparent to those skilled in the art can be made to the disclosed embodiments without departing from the spirit and scope of the invention as set forth in the appended claims.
    权利要求:
    Claims (5)
    [1]
    A fully automatic enzyme immunoassay and luminescence dual system analyzer comprising a housing (1) and a workbench (2), characterized by: - a suction nozzle rack (3), a sample and reagent rack (4), a needle removal rack ( 5), a vibration incubator (6), a plate washer (7) and a luminescence instrument (8) placed on the workbench (2) according to a placement order; - cover plate racks (20) mounted on an outer workbench (2) of the vibration incubator (6); and - an ELIASA (10) mounted on an inner workbench (2) of the vibration incubator (6).
    [2]
    The dual-system analyzer according to claim 1, wherein: - an X-direction guide wire (12) is arranged on a long side of the housing (1); - a Y-direction guideway (13) is arranged on the X-direction guideway (12); - a sample bathing device and a manipulator device are arranged on two sides of the Y-direction guide path (13); - the bathing device comprises a movable arm (14) and a sample addition needle (15); - the movable arm (14) is arranged on the Y-direction guide wheel (13); - the sample addition needle (15) is mounted on a lower end of the movable arm (14); - the manipulator device comprises a manipulator holder (18) and a manipulator (19); - the manipulator holder (18) is arranged on the Y-direction guide path (13); and - the manipulator (19) is arranged on a lower end of the manipulator holder (18).
    [3]
    The dual system analyzer according to claim 1, wherein: - a needle insertion groove (16) is provided on an upper top surface of the needle removal rack (5); - the size of the needle insertion groove (16) is larger than the maximum diameter of a nozzle; - a needle clamping hole (17) is provided on an edge of the needle insertion groove (16); and - the size of the needle clamping hole (17) is smaller than the maximum diameter of the nozzle.
    [4]
    The dual-system analyzer according to claim 1, wherein: - the interior of the luminescence instrument (8) is provided with a luminescence plate mounting position (9); and - the luminescent instrument (8) can be slid out or withdrawn at the luminescent plate mounting position (9).
    [5]
    The dual system analyzer according to claim 1, wherein: - the interior of the ELIASA (10) is provided with an ELIASA plate mounting position (11); and - the ELIASA (10) can be slid out or withdrawn at the ELIAS A plate mounting position (11).
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    同族专利:
    公开号 | 公开日
    NL2023060B1|2019-12-11|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    NL2022088|2018-11-29|
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