• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The invention relates to a method for reducing a subcutaneous fat tissue volume of a skin area of a subject, said method comprising a step of aspirating the skin area previously covered with a wipe impregnated with a liquid or semi-solid composition comprising an anticellulite active in a cavity of a cooling device and a step of cooling the subcutaneous fat tissue volume so as to harden said volume of subcutaneous fat tissue of said skin area. The invention also relates to a wipe pre-impregnated with a liquid or semi-solid composition for the implementation of a method for reducing a volume of subcutaneous fat tissue by the cold, characterized in that said composition is in liquid or semi-solid form at a temperature between -12 ° C and 20 ° C and in that said composition comprises at least one anticellulite active.
    公开号:FR3061012A1
    申请号:FR1663428
    申请日:2016-12-27
    公开日:2018-06-29
    发明作者:Herbert SAMSON
    申请人:DELEO；
    IPC主号:
    专利说明:

    Holder (s):
    DELEO Limited liability company.
    O Extension request (s):
    ® Agent (s): CABINET PLASSERAUD.
    (54) METHOD FOR REDUCING A SUBCUTANEOUS VOLUME BY COLD USING ANTI-CELLULITE ACTIVE.
    FR 3,061,012 - A1 (57) The invention relates to a method for reducing a volume of subcutaneous fatty tissue in a skin area of a subject, said method comprising a step of suctioning the skin area beforehand covered with a wipe impregnated with a liquid or semi-solid composition comprising an anti-cellulite active agent in a cavity of a cooling device and a step of cooling the volume of subcutaneous fatty tissue so as to harden said volume of fatty tissue subcutaneous of said skin area.
    The invention also relates to a wipe pre-impregnated with a liquid or semi-solid composition for implementing a process for reducing a volume of subcutaneous fatty tissue by cold, characterized in that said composition is in liquid or semi-solid form at a temperature between - 12 ° C and 20 ° C and in that said composition comprises at least one anti-cellulite active.

    Field of the invention
    The invention relates to the field of aesthetic treatment of the silhouette of the human body.
    More specifically, the invention relates to a method for reducing a volume of subcutaneous fatty tissue by cold, in which a wipe and a liquid or semi-liquid composition comprising an anticellulite active agent and the liquid are applied to an area of skin to be treated. cooling said skin area so as to cause apoptosis of the fat cells of said skin area. The invention also relates to a wipe pre-impregnated with said composition, in particular for the implementation of said method.
    Technical background
    Cryolipolysis® is a non-invasive technique for permanent reduction of localized subcutaneous fat by the cold. It thus allows to shape the silhouette of a patient, that is to say the contours of the body, according to the following principle.
    Fat cells are vulnerable to cold as they are rich in saturated fatty acids. When they are cooled to a temperature less than or equal to 4 ° C for a sufficient time, a phenomenon of crystallization of the triglycerides contained in the fat cells (also called adipocytes) is observed. The crystallization of triglycerides gradually leads to destruction of the fat cells which thus enter into a phenomenon of apoptosis, that is to say programmed cell death. Since fat cells are naturally more sensitive to cold than other tissues, this cold technique mainly treats fat without damaging the skin and without damaging the other tissues contained in the human body.
    The fat cells or adipocytes thus destroyed are then drained and eliminated via the lymphatic system during the weeks which follow the treatment.
    There are various machines available on the market for reducing the volume of subcutaneous fatty tissue in the cold. The Applicant markets for example a machine under the brand name CRISTAL®, which comprises two handpieces making it possible to cool two localized zones at the same time, which makes it possible to reduce the duration of a session. A session typically takes place in the following manner: the area of skin to be treated is covered with a wipe previously impregnated with a gel; then the handpiece of the machine is affixed to this wipe. This gradually sucks the greasy bead into a cavity and cools it. The duration of the session with this machine varies from a few minutes to an hour depending on the area to be treated. A cold-indented bead is obtained at the end of the session. The practitioner then performs an energetic massage of the bead to break the fat cells and for the skin to return to its normal appearance. You can also then expose the treated area to LED (light-emitting diode) light for about ten minutes to avoid any inflammation. In a few weeks, the fat cells are destroyed and gradually eliminated in the place where the treatment was carried out. This elimination will continue for two to three months. The final result is therefore appreciated after about 3 months.
    Such a process thus eliminates 30% to 50% of the volume of subcutaneous fat which is located in the hypodermis of the skin. However, with this process it is difficult to reach the fat lobules located deep in the hypodermis which are responsible for the phenomenon of orange peel skin which is also known by the term "cellulite". The orange peel phenomenon is mainly found in women and is explained by a structural difference in the partitions of the adipose lobules which store the adipocytes. In men, the partitions are vertical and parallel to each other, while in women the partitions of the lobules produce a rhombus, a point of which is anchored under the dermis. Therefore when the lobules are distended by the mass of adipocytes engorged with triglycerides, the woman's skin takes on the appearance of a padded tissue called orange peel.
    We know the anti-cellulite creams that we apply to the skin, which contain an anti-cellulite active facilitating the destocking of fat cells and slowing their multiplication, such as caffeine. However, these creams have limited effectiveness because the anti-cellulite active has difficulty reaching the hypodermis where the fat lobules responsible for the appearance of orange peel are located.
    There is therefore a need to improve the effectiveness of anti-cellulite creams by widening their field of action.
    There is also a need to perfect current techniques for reducing the volume of subcutaneous fatty tissue by cold so that they are more effective in treating cellulite.
    Summary of the invention
    The invention meets these needs.
    It relates to a method for reducing a volume of subcutaneous fatty tissue of a skin area of a subject, said method comprising the following steps:
    A1) Supply of a pre-impregnated wipe with a liquid or semi-solid composition, said composition comprising an anti-cellulite active, then covering of the skin area with the pre-impregnated wipe; or
    A2) Supply of a wipe and a liquid or semi-solid composition comprising an anti-cellulite active, then application of the liquid or semi-solid composition comprising an anti-cellulite active to the skin area, then application of the wipe to the area skin covered with the liquid or semi-solid composition comprising an anti-cellulite active;
    B) Supply of a cooling device having an external surface and provided with an open cavity delimited by an internal wall and a border on said external surface, then application of the border of the cavity of the cooling device on the wipe so closing the cavity with the assembly consisting of the wipe and the skin area;
    C) Aspiration of the area of skin covered with a wipe in the cavity of the cooling device and cooling of the volume of subcutaneous fatty tissue so as to harden said volume of subcutaneous fatty tissue.
    The invention also relates to a wipe impregnated with a liquid or semi-solid composition, in particular for the implementation of this method, characterized in that said composition is in liquid or semi-solid form at a temperature between - 12 ° C. and 20 ° C and in that said composition comprises at least one anti-cellulite active.
    Without wishing to be linked to a particular theory, it is assumed that when the skin area covered with the wipe is aspirated, the skin is very tight, as a result of which the pores of the skin open more widely. , which facilitates the penetration of the anti-cellulite active through the skin and which allows it to reach more deeply the fatty lobules. Thanks to the method according to the invention, the composition which comprises the anti-cellulite active ingredient is thus much more effective against cellulite than when it is simply applied to an area of skin at rest, that is to say not stretched. The method according to the invention therefore combines a technique of reducing a volume of subcutaneous fatty tissue in an area of skin by the cold and an anticellulite treatment in the same area which is potentiated by the suction of the skin. during the implementation of the process. The anti-cellulite active ingredient also facilitates the drainage and elimination of adipocytes and thus prevents their restocking in the skin.
    Figures
    FIG. 1 represents the step of applying the cooling device to the area of skin to be treated, which has previously been covered with a wipe pre-impregnated with the composition containing the anti-cellulite active.
    FIG. 2 represents the suction step of the skin area covered with a wipe pre-impregnated with the composition containing the anti-cellulite active agent in the cavity of the cooling device.
    Detailed description of the invention
    According to a first aspect, the invention relates to a non-therapeutic method for reducing a volume of subcutaneous fatty tissue in a skin area of a subject, said method comprising steps A1) or A2), B) and C) as defined above.
    The skin has three layers: the epidermis (the surface layer), the dermis (the middle layer) and the hypodermis (the deep layer). The term "subcutaneous fatty tissue" means a fatty tissue located in the hypodermis, that is to say the deepest layer of the skin.
    The method according to the invention makes it possible to treat all the areas of skin having an adipose bead of which it is desired to reduce the volume, such as the hips, in particular the areas which are commonly called "love handles", the belly , the buttocks, in particular the area called the breeches, the knees, the thighs, the arms, the folds of the back, the chest or even the double chin.
    In a first step, two embodiments are possible: either we perform step A1), or we perform step A2).
    Step A1): there is a wipe pre-impregnated with a liquid or semi-solid composition, said composition comprising an anti-cellulite active, then the area of skin to be treated is covered with the pre-impregnated wipe.
    Step A2): there is a wipe on the one hand and a liquid or semi-solid composition comprising an anti-cellulite active on the other hand. Then the liquid or semi-solid composition comprising an anti-cellulite active is applied to the skin area to be treated, then said wipe is applied to the skin area covered with the liquid or semi-solid composition comprising an anti-cellulite active.
    The wipe avoids direct contact between the skin area and the cooling device (which will be described below) and also makes it possible to retain the gel during the aspiration step (which will be described below) .
    In a second step B) of the method according to the invention shown in FIG. 1, there is a cooling device 1 having an exterior surface 2 and provided with an open cavity 3 delimited by an interior wall 4 and a border 5 on said outer surface 2, then the border 5 of the cavity 3 of the cooling device 1 is applied to the wipe 6 so as to close the cavity 3 with the wipe 6 which covers the area of skin to be treated 7. Contact between the edge 5 and the wipe 6 is made so that the closure of the cavity 3 is sealed. The cooling device 1 is provided with a suction system in communication with the cavity 3 through the orifice 8 enabling the air which is included in the cavity 3 to be drawn.
    The cavity 3 can be in various shapes and sizes, which one chooses according to the area of the body to be treated and the subject's morphology. For example, to treat the bulges of the hip, the cavity will preferably have an elongated shape, such as for example the shape of a rectangular parallelepiped with rounded tops or a similar shape of oval section. The length and width of the cavity can be respectively between 4 cm and 30 cm and 2 cm and 5 cm.
    In a third step C) of the method according to the invention shown in FIG. 2, the skin area 7 covered with the wipe is aspirated using the suction system in the cavity 3 of the cooling device 1. Thanks to the tight contact between the edge 5 of the cavity 3 and the wipe 6 which covers the skin area 7, the suction of the air included in the cavity 3 makes it possible to draw the skin area 7 inside the cavity 3 and thus bring up a volume of subcutaneous fatty tissue 71 inside said cavity 3. In this way, the fatty fold is isolated from the rest of the body, which increases the cooling efficiency and makes it possible not to cool. organs. The suction is maintained and this volume of fatty tissue is cooled until the volume of fatty tissue hardened by the cold is obtained.
    In FIGS. 1 and 2, the wipe is pre-impregnated with a liquid or semi-solid composition as described above. Alternatively, and as described above, one can first apply the liquid or semi-solid composition comprising an anti-cellulite active agent to the area of skin to be treated, then apply a wipe to the area of skin covered with the liquid or semi-solid composition comprising an anti-cellulite active.
    Fat cell apoptosis can be induced in particular from 4 ° C. The temperature of the interior wall 4 of the cavity 3 of the cooling device 1 during the cooling of the volume of subcutaneous fatty tissue is therefore between -12 ° C and 4 ° C, more particularly between -9 ° C and 0 ° vs.
    The cooling time depends on the temperature applied to the skin area and the size of the bead to be treated. Depending on the type of bead to be treated, the volume of subcutaneous fatty tissue can be cooled for a time between 40 minutes and 100 minutes.
    The suction is carried out at a pressure typically between 100 mbar and 1000 mbar, in particular between 150 mbar and 900 mbar, more particularly between 700 mbar and 1000 mbar.
    The pressure level between 700 mbar and lOOOmbar which is higher than the suction levels of known devices for reducing fat by cold, is particularly advantageous in order to guarantee an improvement in the penetration of the anti-cellulite active agent into the skin.
    For example, the processing time to process the love handles will typically be around 60 minutes, under a suction pressure of 480 mbar and at a temperature of - 6 ° C.
    After obtaining a volume of fatty tissue hardened by the cold, the suction is stopped and the cooling device is detached from the skin area, then the wipe is removed. The practitioner can then perform an energetic massage of the hardened bead to break the fat cells, stimulate the lymphatic drainage and so that the skin returns to its normal appearance.
    One can also then expose the treated area to a heating device, for example an LED light, in particular for ten minutes to avoid any inflammation of the skin.
    Broken fat cells are gradually eliminated by the body.
    For areas of skin that are difficult to vacuum, such as the breeches of some patients, the cooling device does not include a cavity or suction system, but has a flat surface. This flat surface is applied to the area to be treated and the cooling device is kept in this position by compression using a strap, until a volume of fatty tissue is hardened by the cold.
    According to a second aspect, the invention relates to a wipe pre-impregnated with a liquid or semi-solid composition intended to be used in a process for reducing a subcutaneous fatty volume by cold, in particular for the implementation of the process according to the invention.
    The wipe according to the invention is impregnated with a composition which is in liquid or semi-solid form at a temperature between -12 ° C and 20 ° C and which comprises at least one anti-cellulite active.
    The liquid or semi-solid composition comprising an anti-cellulite active makes it possible to constitute an anti-freeze barrier for the skin and prevents the skin from being burned during the cooling step. Indeed, a phenomenon of condensation can cause the presence of water on the surface of the skin, thus causing a formation of frost on the skin when the latter is subjected to negative temperatures. This formation of frost can cause skin burns. The liquid or semi-solid composition acts as an antifreeze with regard to the layer of water present on the skin and thus makes it possible to avoid burns which could cause cooling.
    The wipe according to the invention is formed from a flexible material capable of being impregnated with a liquid or semi-liquid composition.
    This material can be a textile (fabric, knitted or non-woven) made of natural fibers, synthetic or semi-synthetic fibers or a mixture of these. Natural fibers can be chosen from cotton, silk, or cellulose. Synthetic or semi-synthetic fibers can be chosen from polyolefins, polyesters, rayon, polyamides, poly (ester amide) s or polyvinyl alcohols.
    The volume of liquid or semi-solid composition applied to the skin area depends on the surface to be treated and can therefore range from 5 to 25 cl.
    The prepreg wipe comprises an amount of liquid or semi-solid composition which can be between 5% and 95% by weight, in particular between 10% and 80% by weight.
    The liquid or semi-solid composition containing an anti-cellulite active agent is formulated from an excipient or a mixture of excipients which do not freeze at a temperature between - 12 ° C and 20 ° C.
    Preferably, the liquid or semi-solid composition containing an anti-cellulite active agent is formulated so as to be able to be easily applied to the skin, to be pleasant to the touch and to be easily eliminated when the session is finished.
    For example, when it is liquid, the composition can be prepared from a liquid excipient or a mixture of liquid excipients, such as glycerin, alcohols such as ethanol or isopropanol, or also from propylene glycol, polyethylene glycol or oils such as sesame oil, corn oil, soybean oil, or medium chain triglycerides.
    When it is semi-solid, the composition can be a gel, an ointment (monophasic excipient), a paste (semi-solid preparation containing a high proportion of powder finely dispersed in the excipient) or a cream (multiphasic preparation).
    A gel is a preparation made up of liquids which are gelled using suitable gelling agents. A gel can be a hydrophobic gel (oleogel) or a hydrophilic gel (hydrogel). A hydrophobic gel can be prepared from liquid paraffin, polyethylene and fatty oils gelled with colloidal silica. A hydrophilic gel can be prepared from hydrophilic solvents, such as water, glycerin, propylene glycol, and gelling agents, such as carrageenan, gelatin, cellulose gel, a carbomer or else thickeners or viscosity agents such as alginates, cellulose derivatives, carboxyvinilic polymers, or xanthan gum.
    An ointment can be lipophilic, water absorbent or hydrophilic. A lipophilic ointment can be prepared from hydrocarbons, such as petroleum jelly or paraffin oil, vegetable oils, such as sweet almond oil or olive oil, or waxes, such as than beeswax or synthetic wax. A water absorbing ointment can be prepared from hydrophobic excipients and water / oil emulsifiers, fatty alcohols, such as ketostearil alcohol or lanolin. Hydrophilic ointment can be prepared from water-miscible excipients, such as high molecular weight macrogols.
    A paste can be lipophilic or hydrophilic. A lipophilic paste can be prepared from a fatty substance or a mixture of fatty substances, such as for example lanolin or petroleum jelly, and an at least 50% of powder, such as zinc oxide or wheat starch. A hydrophilic paste will be prepared from a water-based or water-miscible excipient.
    A cream is a multiphasic preparation, generally consisting of a lipophilic phase and a hydrophilic phase. To stabilize the two phases, it is necessary to add one or more surfactants, such as for example sodium lauryl sulfate or sorbitan esters, and a thickening agent or viscosity agent, as mentioned above.
    The anti-cellulite active agent is chosen from active agents which promote lipolysis and / or drainage and are in particular chosen from caffeine, green tea, ginkgo biloba, Andiroba extracts, small holly, ivy, seaweed , or the essential oil of Eucalyptus Dives.
    According to a particular embodiment, the liquid or semi-solid composition containing an anti-cellulite active agent further comprises salicylic acid which makes it possible to improve the visual appearance of the skin and in particular to make it visually younger.
    The liquid or semi-solid composition containing an anti-cellulite active agent can also comprise other additives such as preservatives or neutralizers.
    The liquid or semi-solid composition containing an anti-cellulite active agent is preferably a hydrogel comprising glycerin, a carbopol® (carbomer) as gelling agent, xanthan gum as thickener, and as active principles of caffeine, a green tea extract. and salicylic acid.
    According to a particular embodiment, the liquid or semi-solid composition containing an anti-cellulite active agent comprises:
    - from 30% to 60% by weight of a solvent such as glycerin;
    - from 0.1% to 1% by weight of a gelling agent such as a carbomer;
    - from 0.1% to 1% by weight of a thickener such as xanthan gum;
    - from 0.1% to 1% by weight of a preservative;
    - 0.1 to 10% by weight of an anti-cellulite active ingredient such as caffeine or a green tea extract;
    - 0.1 to 5% by weight of salicylic acid;
    - a sufficient amount of water to obtain 100%.
    The prepreg wipe according to the invention can be packaged in a sealed bag which contains a single wipe or in a sealed package which contains several wipes. In the sachet or the package, it can be in folded form, in particular by interlacing, or folded in Z, in W, or in Z then in half. The prepreg wipe can also be packaged in boxes, refills or buckets.
    The prepreg according to the invention can be in various shapes and sizes, for example in the form of a rectangular sheet of length approximately equal to 30 cm and width approximately equal to 20 cm.
    According to a third aspect, the invention relates to a method for preparing the prepreg wipe according to the invention, as described above, characterized in that a wipe is impregnated with a composition in liquid or semi form -solid at a temperature between - 12 ° C and 20 ° C and comprising at least one anti-cellulite active.
    The impregnation step is carried out so as to make the composition penetrate into the structure of the wipe.
    In particular, the composition is spread over the surface of the wipe evenly.
    According to a first embodiment, the impregnation step can be carried out before packaging the wipe in a sealed package.
    For example, the wipes are placed continuously on a conveyor belt and the liquid or semi-solid composition containing an anti-cellulite active agent according to the invention is poured onto said wipes so as to deposit a sufficient amount on the wipe and to impregnate, to permeate. Then, said impregnated wipes are conditioned in their packaging using a packaging machine.
    According to a second embodiment, the impregnation step can be carried out after packaging of the wipes. The non-impregnated wipes are placed in a packaging machine, then the liquid or semi-solid composition containing an anti-cellulite active agent according to the invention is injected into the packaging of the wipes in order to impregnate them.
    According to a fourth aspect, the invention relates to the use of the prepreg wipe according to the invention, as described above, for reducing a volume of subcutaneous fatty tissue of a skin area of a subject in a method of reduction of a subcutaneous fatty volume by the cold.
    The term “method for reducing a volume of subcutaneous fatty tissue by cold” means a method making it possible to reduce a volume of fatty tissue subcutaneous from a skin area of a subject by subjecting said volume of tissue greasy at a temperature between -12 ° C and - 4 ° C using a non-invasive cooling device.
    According to a particular embodiment, said method of reducing a volume of subcutaneous fatty tissue by cold comprises the following steps:
    A) Supply of a prepreg wipe according to the invention, then covering of the skin area with the prepreg wipe;
    B) Supply of a cooling device having an external surface and provided with an open cavity delimited by an internal wall and a border on said external surface, then application of the border of the cavity of the cooling device on the wipe so closing the cavity with the assembly consisting of the wipe and the skin area;
    C) Aspiration of the area of skin covered with the wipe in the cavity of the cooling device and cooling of the volume of subcutaneous fatty tissue so as to harden said volume of subcutaneous fatty tissue.
    According to a fifth aspect, the invention relates to a composition in liquid or semi-solid form at a temperature between - 12 ° C and 20 ° C comprising at least one anti-cellulite active, for its use in a process for reducing a volume cold subcutaneous fatty tissue.
    According to a particular embodiment, said method of reducing a volume of subcutaneous fatty tissue by cold comprises the following steps:
    A1) Supply of a wipe pre-impregnated with said liquid or semi-solid composition, then covering of the skin area with the pre-impregnated wipe; or
    A2) Supply of a wipe and of said liquid or semi-solid composition, then application of said liquid or semi-solid composition to the skin area, then application of the wipe to the skin area covered with said liquid or semi composition -solid;
    B) Supply of a cooling device having an external surface and provided with an open cavity delimited by an internal wall and a border on said external surface, then application of the border of the cavity of the cooling device on the wipe so closing the cavity with the assembly consisting of the wipe and the skin area;
    C) Suction of the area of skin covered with a wipe in the cavity of the cooling device and cooling of the volume of subcutaneous fatty tissue so as to harden said volume of subcutaneous fatty tissue.
    According to a sixth aspect, the invention relates to an anti-cellulite active agent for its use in a process for reducing a volume of subcutaneous fatty tissue by cold.
    According to a particular embodiment, said method of reducing a volume of subcutaneous fatty tissue by cold comprises the following steps:
    A1) Supply of a wipe pre-impregnated with a liquid or semi-solid composition, said composition comprising said anti-cellulite active, then covering of the skin area with the pre-impregnated wipe; or
    A2) Supply of a wipe and a liquid or semi-solid composition comprising said anti-cellulite active, then application of said liquid or semi-solid composition comprising said anti-cellulite active to the skin area, then application of the wipe to the area skin covered with said liquid or semi-solid composition comprising said anti-cellulite active;
    B) Supply of a cooling device having an external surface and provided with an open cavity delimited by an internal wall and a border on said external surface, then application of the border of the cavity of the cooling device on the wipe so closing the cavity with the assembly consisting of the wipe and the skin area;
    C) Aspiration of the area of skin covered with a wipe in the cavity of the cooling device and cooling of the volume of subcutaneous fatty tissue so as to harden said volume of subcutaneous fatty tissue.
    Example
    A hydrogel is prepared having the following composition:
    Ingredient Property Quantity (% by mass) Glycerin Solvent / humectant 40 Carbopol Ultrez 21Polymer Gelling agent 0.6 Xanthan gum Thickening 0.15 Sodium benzoate Conservative 0.5 NaOH soda Neutralizing Qsp pH = 7 Green tea extract Active 1 Caffeine Active 3 Salicylic acid Active 2 Water - Qsp 100
    The gel is made cold by gradually adding all of the above ingredients to water in a vacuum mixer.
    权利要求:
    Claims (13)
    [1" id="c-fr-0001]
    Claims
    1. A method for reducing a volume of subcutaneous fatty tissue (71) of a skin area (7) of a subject, said method comprising the following steps:
    A1) Supply of a wipe (6) pre-impregnated with a liquid or semi-solid composition, said composition comprising an anti-cellulite active, then covering of the skin area (7) with the pre-impregnated wipe (6); or
    A2) Supply of a wipe and a liquid or semi-solid composition comprising an anti-cellulite active, then application of the liquid or semi-solid composition comprising an anti-cellulite active to the skin area (7), then application of the wipe on the skin area covered with the liquid or semi-solid composition comprising an anti-cellulite active;
    B) Supply of a cooling device (1) having an external surface (2) and provided with an open cavity (3) delimited by an internal wall (4) and an edge (5) on said external surface (2) , then application of the edge (5) of the cavity of the cooling device on the wipe (6) so as to close the cavity (3) with the assembly consisting of the wipe (6) and the skin area (7 );
    C) Suction of the skin area (7) covered with a wipe (6) in the cavity (3) of the device for cooling and cooling the volume of subcutaneous fatty tissue so as to harden said volume of subcutaneous fatty tissue skin.
    [2" id="c-fr-0002]
    2. Method according to claim 1, characterized in that the temperature of the internal wall (4) of the cavity (3) of the cooling device during the cooling of the volume of subcutaneous fatty tissue is between -12Ό and 4 ° vs.
    [3" id="c-fr-0003]
    3. Method according to claim 1 or 2, characterized in that the volume of subcutaneous fatty tissue is cooled for a time between 40 minutes and 100 minutes.
    [4" id="c-fr-0004]
    4. Method according to any one of claims 1 to 3, characterized in that the suction is carried out at a pressure between 100 mbar and 1000 mbar, in particular between 150 mbar and 900 mbar.
    [5" id="c-fr-0005]
    5. Method according to any one of claims 1 to 4, characterized in that the skin area is chosen from the hips, the belly, the buttocks, the knees, the thighs, the arms, the folds of the back, the chest , the double chin.
    [6" id="c-fr-0006]
    6. Wipe pre-impregnated with a liquid or semi-solid composition intended to be used in a process for reducing a volume of subcutaneous fatty tissue by cold, characterized in that said composition is in liquid or semi form -solid at a temperature between - 12 ° C and 20 ° C and in that said composition comprises at least one anticellulite active.
    [7" id="c-fr-0007]
    7. Wipe according to claim 6, characterized in that the anti-cellulite active agent is chosen from caffeine, green tea, ginkgo biloba, Andiroba extracts, small holly, ivy, seaweed, or else l essential oil of Eucalyptus Dives.
    [8" id="c-fr-0008]
    8. A wipe according to claim 6 or 7, characterized in that the semi-solid composition is a gel, an ointment, a paste or a cream.
    [9" id="c-fr-0009]
    9. Wipe according to any one of claims 6 to 8, characterized in that said composition comprises water, glycerin or propylene glycol, alcohols such as ethanol or isopropanol, or an oil such than sesame oil, corn oil, soybean oil, or medium chain triglycerides.
    [10" id="c-fr-0010]
    10. Wipe according to any one of claims 6 to 9, characterized in that said composition comprises a gelling agent such as carrageenan, gelatin, cellulose gel, a carbomer or a thickener or viscosity agent such as an alginate, a cellulose derivative, a carboxyvinilic polymer, or a xanthan gum.
    [11" id="c-fr-0011]
    11. A wipe according to any one of claims 6 to 10, characterized in that said composition further comprises salicylic acid.
    [12" id="c-fr-0012]
    12. Method for preparing the wipe according to any one of claims 6 to 11, characterized in that a wipe is impregnated with a composition in liquid or semi-solid form at a temperature between - 12 ° C and 20 ° C and comprising at least one anti-cellulite active.
    [13" id="c-fr-0013]
    13. Use of the wipe according to any one of claims 6 to 11, for reducing a volume of subcutaneous fatty tissue of a skin area of a subject 5 in a method of reducing a volume of fatty tissue subcutaneous by cold.
    1/1
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    同族专利:
    公开号 | 公开日
    WO2018122535A1|2018-07-05|
    FR3061012B1|2020-02-14|
    引用文献:
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    US10478633B2|2015-07-01|2019-11-19|Btl Medical Technologies S.R.O.|Aesthetic method of biological structure treatment by magnetic field|
    US10596386B2|2016-07-01|2020-03-24|Btl Medical Technologies S.R.O.|Aesthetic method of biological structure treatment by magnetic field|
    US10632321B2|2016-07-01|2020-04-28|Btl Medical Technologies S.R.O.|Aesthetic method of biological structure treatment by magnetic field|
    US10695575B1|2016-05-10|2020-06-30|Btl Medical Technologies S.R.O.|Aesthetic method of biological structure treatment by magnetic field|
    US10695576B2|2015-07-01|2020-06-30|Btl Medical Technologies S.R.O.|Aesthetic method of biological structure treatment by magnetic field|
    US10709895B2|2016-05-10|2020-07-14|Btl Medical Technologies S.R.O.|Aesthetic method of biological structure treatment by magnetic field|
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    法律状态:
    2017-10-27| PLFP| Fee payment|Year of fee payment: 2 |
    2018-06-29| PLSC| Search report ready|Effective date: 20180629 |
    2018-10-26| PLFP| Fee payment|Year of fee payment: 3 |
    2020-03-30| PLFP| Fee payment|Year of fee payment: 4 |
    2020-11-30| PLFP| Fee payment|Year of fee payment: 5 |
    2021-03-19| PLFP| Fee payment|Year of fee payment: 6 |
    优先权:
    申请号 | 申请日 | 专利标题
    FR1663428A|FR3061012B1|2016-12-27|2016-12-27|METHOD FOR REDUCING A FAT SUBCUTANEOUS VOLUME BY COLD USING ANTI-CELLULITE ACTIVE|
    FR1663428|2016-12-27|FR1663428A| FR3061012B1|2016-12-27|2016-12-27|METHOD FOR REDUCING A FAT SUBCUTANEOUS VOLUME BY COLD USING ANTI-CELLULITE ACTIVE|
    PCT/FR2017/053855| WO2018122535A1|2016-12-27|2017-12-27|Method for reducing a subcutaneous fat volume by means of cold using an anti-cellulite active ingredient|
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