• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The present invention relates to a device for use in the processing of fatty tissue characterized in that it comprises in a closed circuit a first tissue collection unit (1), connected to a second tissue collection unit (2), where the first tissue collection unit (1) has an opening (3) that allows tissue to enter and an opening (4) at the base of the first unit that allows tissue to exit, and where the second tissue collection unit (2) has an opening (6) at the base of the second unit, which allows the tissue to exit. (Machine-translation by Google Translate, not legally binding)
    公开号:ES2738956A1
    申请号:ES201830769
    申请日:2018-07-26
    公开日:2020-01-27
    发明作者:David Cohen
    申请人:Disentropic S L；
    IPC主号:
    专利说明:

    [0001]
    [0002]
    [0003]
    [0004] BACKGROUND
    [0005]
    [0006] Adipose tissue or fatty tissue is loose connective tissue mostly composed of adipocytes or fat cells. The fatty tissue can be removed from the body by liposuction and is useful both in aesthetic and reconstructive procedures and for the isolation and treatment of the vasculo-stromal fraction (EVD) or other fractions derived from its centrifugation.
    [0007]
    [0008] The fatty tissue is removed from the body by liposuction, where a hollow cannula comprising an opening at or near its free end is inserted into the region of the body to be treated through a small incision in the skin. The fat cells are aspirated through the light of the cannula that is connected to a vacuum source and is therefore led to a container. Once the fatty tissue is obtained, it can be used directly or manipulated to select the size of the fat cells, isolate a certain group of cells, etc.
    [0009]
    [0010] There is a need for simple and low-cost devices that serve to collect the fatty tissue obtained in a liposuction and allow its selection in a closed circuit.
    [0011]
    [0012] DESCRIPTION OF THE INVENTION
    [0013]
    [0014] The present invention is a simple and low cost solution, since it represents a device that, in a closed circuit, allows collecting and, if desired, selecting the fatty tissue from a liposuction based on the size of the fat globules. In addition, the device of the present invention allows the tissue to be separated from the liquid medium comprising blood and anesthesia, and even to wash said fatty tissue, all always in a closed circuit system.
    [0015]
    [0016] Thus, in a first aspect, the present invention relates to a device for use in the processing of fatty tissue characterized in that it comprises in a closed circuit a first tissue collection unit (1), connected to a second unit of tissue collection (2), where the first tissue collection unit (1) has an opening (3) that allows tissue to enter and an opening (4) at the base of the first unit that allows tissue to exit, and where the second tissue collection unit (2) has an opening (6) at the base of the second unit, which allows tissue to exit.
    [0017]
    [0018] The fact that the device is a closed circuit system has the advantage that the tissue being processed is not exposed to contamination by any external agent.
    [0019]
    [0020] The openings of the device of the present invention allow the coupling of an extension or extension or cannula, due to its tubular shape.
    [0021]
    [0022] In a preferred embodiment, the opening (3) is located at the top of the first tissue collection unit (1).
    [0023]
    [0024] In a preferred embodiment of the first aspect of the present invention, the first tissue collection unit (1) is connected to a second tissue collection unit (2) through a filter (7). Preferably, the filter (7) has a pore size between 100 and 200 microns, preferably 150 ± 5 microns.
    [0025]
    [0026] Preferably, the device (except the filter) is made of biocompatible plastic material, such as a thermoplastic polymer such as polyethylene, polypropylene or a copolymer of polypropylene and ethylene, preferably a random or random copolymer of polypropylene and ethylene. The filter, however, consists of a mesh and is preferably made of biocompatible material, such as stainless steel with 0.1 mm wire and a mesh light between 0.1 and 0.2 mm, preferably with a light 0.15 ± 0.005 mm.
    [0027]
    [0028] In another preferred embodiment of the first aspect of the present invention, the second tissue collection unit (2) has in its upper part, immediately below the filter, an opening (5). Said opening (5) allows aspiration by syringe or by vacuum pump. Therefore, in another preferred embodiment of the first aspect of the present invention, the device further comprises means for making the vacuum coupled to the opening (5).
    [0029] In another preferred embodiment of the first aspect of the present invention, the device further comprises a cannula coupled to the opening (3). Preferably, the device further comprises a three-way key coupled to the cannula. Said cannula coupled to the three-way key allows the direct transfer of fatty tissue that is aspirated with a syringe to the first tissue collection unit (1).
    [0030]
    [0031] In a second aspect, the present invention relates to the use of the device of the first aspect for the processing of fatty tissue. Preferably, said fatty tissue is used in biolipoplasty, obtaining the vasculo-stromal fraction, stem cell isolation or isolation of fractions of fine fatty tissue for the treatment of fine wrinkles, rhinomodelation or autologous cosmetic manufacturing.
    [0032]
    [0033] DESCRIPTION OF THE FIGURES
    [0034]
    [0035] Figure 1. Device of the present invention.
    [0036]
    [0037] EXAMPLES
    [0038]
    [0039] This invention will be better understood by reference to the examples below, but those skilled in the art will readily appreciate that the specific detailed examples are only illustrative of the invention.
    [0040]
    [0041] Example 1:
    [0042] By connecting an extension / extension of the usual infusion systems by one of its ends in the opening (3) and the other to a 3-way wrench and this to a 20 or 50 cm3 syringe, the fatty tissue is aspirated and by The action of our key transfers the contents of the aspiration syringe to the first tissue collection unit (1). This is repeated as many times as necessary until the desired tissue volume is obtained.
    [0043]
    [0044] On the one hand, if we let the volume of tissue aspirated on the filter (7) be decanted by simple gravity, we obtain in the first tissue collection unit (1) a complete fatty tissue with globules of different sizes, perfectly usable for lipotransference, biolipoplasty , obtaining the vasculo-stromal fraction, isolation of stem cells or isolation of other fractions of fatty tissue.
    [0045] We can also obtain globules of different sized fatty tissue with different objectives if after vacuuming with a syringe we apply a vacuum in the opening (5) to
    [0046] create a negative pressure inside the second tissue collection unit (2), which will pass the finest fatty tissue globules through the filter.
    [0047]
    [0048] Once we observe the supernatant of fatty tissue in the second tissue collection unit (2), we remove the liquid fraction consisting of anesthetic mixture, blood, etc. through opening (6), since the fatty tissue floats above the liquid and this comes out earlier. In this way, after having extracted the liquid fraction, through the same opening (6) we can extract the fine fatty tissue and collect it directly in syringes of 1 or 3 cm3 and use it directly for treatment of thinner wrinkles, rhinomodelation in combination with gel Plasma, manufacture of autologous cosmetics, etc.
    [0049]
    [0050] On the other hand, the device of the present invention can be used by aspirating or applying vacuum in the opening (5) so that the thick fatty tissue is retained in the first tissue collection unit (1) and the fine fatty tissue passes through the filter and remain in the second tissue collection unit (2).
    [0051] Furthermore, the device of the present invention allows the tissue to be washed, for example, with serum, when introduced through the opening (3).
    [0052]
    [0053] The fatty tissue of the first tissue collection unit (1) can be collected, for example, by syringe through the opening (4), to be used for example in grafts, or to be collected in closed circuit in Falcon type tubes coupled to said opening to be processed later. For example, the fat thus obtained can be processed to obtain stem cells by washing, centrifugation, etc.
    权利要求:
    Claims (9)
    [1]
    1. A device for use in the processing of fatty tissue characterized in that it comprises in closed circuit a first tissue collection unit (1), connected to a second tissue collection unit (2), where the first tissue collection unit tissue (1) has an opening (3) in its upper part and an opening (4) in its base, and where the second tissue collection unit (2) has an opening (6) in its base.
    [2]
    2. The device according to the preceding claim, wherein the first tissue collection unit (1) is connected to a second tissue collection unit (2) through a filter (7).
    [3]
    3. The device according to any of the preceding claims, wherein the first tissue collection unit (1) is connected to a second tissue collection unit (2) through a filter (7), which has a size Pore between 100 and 200 microns.
    [4]
    4. The device according to any of the preceding claims, wherein the second tissue collection unit (2) has an opening (5) in its upper part.
    [5]
    5. The device according to the preceding claim, further comprising means for making the vacuum coupled to the opening (5).
    [6]
    6. The device according to any of the preceding claims, further comprising a cannula coupled to the opening (3).
    [7]
    7. The device according to the preceding claim, further comprising a three-way key coupled to the cannula.
    [8]
    8. Use of the device according to any of the preceding claims for the processing of fatty tissue.
    [9]
    9. Use according to the preceding claim, wherein the processing of fatty tissue is for use in biolipoplasty, obtaining the vasculo-stromal fraction, isolation of stem cells or isolation of fractions of fine fatty tissue for the treatment of fine wrinkles, rhinomodelation or autologous cosmetic manufacturing.
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    同族专利:
    公开号 | 公开日
    WO2020021151A1|2020-01-30|
    EP3815722A4|2021-08-04|
    US20210146018A1|2021-05-20|
    EP3815722A1|2021-05-05|
    ES2738956B2|2022-01-17|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US20030054331A1|2001-09-14|2003-03-20|Stemsource, Inc.|Preservation of non embryonic cells from non hematopoietic tissues|
    WO2011117821A1|2010-03-23|2011-09-29|Carlo Tremolada|A device and a method for preparing a tissue|
    WO2012148502A2|2011-04-28|2012-11-01|Spinesmith Partners Lp|Lipoaspirate stem cell separation system and methods thereof|
    US9358327B1|2015-05-28|2016-06-07|Mark Louis Venturi|Adipose tissue separation device and methods|
    WO2016199149A1|2015-06-10|2016-12-15|The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center|Mechanical apparatus and method for isolating stromal vascular fraction|
    NZ236033A|1989-11-13|1994-11-25|Davol Inc|Blood pump: filtering with tangential flow separation|
    US8414519B2|2008-05-21|2013-04-09|Covidien Lp|Wound therapy system with portable container apparatus|
    法律状态:
    2020-01-27| BA2A| Patent application published|Ref document number: 2738956 Country of ref document: ES Kind code of ref document: A1 Effective date: 20200127 |
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    优先权:
    申请号 | 申请日 | 专利标题
    ES201830769A|ES2738956B2|2018-07-26|2018-07-26|DEVICE FOR THE PROCESSING OF FAT TISSUE AND ITS USES|ES201830769A| ES2738956B2|2018-07-26|2018-07-26|DEVICE FOR THE PROCESSING OF FAT TISSUE AND ITS USES|
    EP19841021.9A| EP3815722A4|2018-07-26|2019-07-26|Device for processing fatty tissue and uses thereof|
    PCT/ES2019/070529| WO2020021151A1|2018-07-26|2019-07-26|Device for processing fatty tissue and uses thereof|
    US17/158,094| US20210146018A1|2018-07-26|2021-01-26|Device for processing fatty tissues and uses thereof|
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