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    • 专利摘要:
    The present invention relates to a method of preparing a plant product comprising at least 0.05% vitamin C on a dry-matter basis, the method comprises the steps of: (i) providing the plant material; (ii) optionally, washing the plant material with a washing liquid; (iii) freezing the plant material to a temperature below 0°C, providing a frozen plant material; (iv) subjecting the frozen plant material to a coarsely chopping process, providing a coarsely chopped and frozen plant material; (v) subjecting the coarsely chopped and frozen plant material to an aqueous extraction solution, providing a liquid coarsely chopped and chilled plant material; (vi) wet grinding the liquid coarsely chopped and chilled plant material, providing the plant produet comprising vitamin C; wherein the vitamin C presentin the plant produet is the vitamin C naturally occurring in the plant material.
    公开号:DK201671020A1
    申请号:DKP201671020
    申请日:2016-12-22
    公开日:2018-08-03
    发明作者:Otto Hansen Torbjørn；Larsen Erik
    申请人:Hyben Vital Licens Aps；
    IPC主号:
    专利说明:

    (19) DANMARK (1°) DK 2016 71020 A1
    (12)
    PATENTANSØGNING
    Patent- og Varemærkestyrelsen lnt.CI.: A61K 36/738 (2006.01) A23L 19/00 (2016.01) A23L 33/10 (2016.01)
    Ansøgningsnummer: PA 2016 71020
    Indleveringsdato: 2016-12-22
    Løbedag: 2016-12-22
    Aim. tilgængelig: 2018-06-23
    Publiceringsdato: 2018-08-03
    Ansøger:
    Hyben Vital Licens ApS, Klavsebøllevej 2,5953 Tranekær, Danmark
    Opfinder:
    Torbjørn Otto Hansen, Klavsebøllevej 2,5953 Tranekær, Danmark
    Erik Larsen, Ravnholtvej 33 Måre, 5853 Ørbæk, Danmark
    Fuldmægtig:
    Larsen & Birkeholm A/S Skandinavisk Patentbureau, Banegårdspladsen 1,1570 København V, Danmark
    Titel: METHOD FOR PREPARING A PRODUCT COMPRISING HIGH AMOUNT OF NATURALLY OCCURING VITAMIN C
    Fremdragne publikationer:
    WO 2016/173995
    WO 2011/113433
    YAVRU, I. et al.
    US 6024960
    Sammendrag:
    The present Invention relates to a method of preparing a plant product comprising at least 0.05% vitamin C on a dry-matter basis, the method comprises the steps of: (i) providing the plant material; (ii) optionally, washing the plant material with a washing liquid; (iii) freezing the plant material to a temperature below 0°C, providing a frozen plant material; (iv) subjecting the frozen plant material to a coarsely chopping process, providing a coarsely chopped and frozen plant material; (v) subjecting the coarsely chopped and frozen plant material to an aqueous extraction solution, providing a liquid coarsely chopped and chilled plant material; (vi) wet grinding the liquid coarsely chopped and chilled plant material, providing the plant produet comprising vitamin C; wherein the vitamin C presentin the plant produet is the vitamin C naturally occurring in the plant material.
    DK 2016 71020 A1 i
    METHOD FOR PREPARING A PRODUCT COMPRISING HIGH AMOUNT OF
    NATURALLY OCCURING VITAMIN C
    S Technical field of the invention
    The present invention relates to a method of preparing a product obtained from a plant material, wherein the product comprises a high content of the naturally occurring nutrients antioxidants and/or polyphenols. In particular, the present invention relates to a method for preparing a rose hip product where a large proportion of the naturally occurring vitamin 10 C has been preserved.
    Background of the invention
    For years, various rose hip formulations have been created to provide various nutritional or 15 pharmacological effects to the mammal (humans or animals) consuming the formulation.
    In US 6,024,960, a rose-hip product was provided having a high content of vitamin C and it was found to alleviate the symptoms associated with inflammation. Specifically, the product was obtained in accordance with a process of drying the milled rose hip under 20 conditions which is aimed at preserved a relatively high vitamin C content as well as the content of several other vitamins.
    Furthermore, WO 03/043613 relates to the use of glycosides of a mono- or diacylglycerol for treatment of Inflammatory diseases, and more particularly to 3-ß-D- gaiactopyranosyloxy-2~(octadeca-9Z, 12Z, 15Z-trienoyloxy)propanyl octadeca9Z,12Z,15Z-trienoate (also known as GOPO) either obtained from natural sources such as rose hips (the fruits of Rosa canina) or prepared by total synthesis, for the treatment of inflammation, such as arthritis. The action of this compound was shown to be alleviating chemiluminescence of polymorphonuclear monocytes and chemotaxis of mononuclear leukocytes, Moreover, It was discovered in WO 03/043613 that this compound could be obtained via an extraction, in particular, an extraction using organic solvents, and a bioguided fractionation procedure of rose-hips which was shown to contain this highly active anti-inflammatory agent. Similar to administering rose-hips orally was shown to efficiently alleviate inflammatory pains an oral formulation of the isolated anti-inflammatory agent was shown to be useful for treatment of symptoms associated with inflammation diseases.
    DK 2016 71020 A1
    While inflammation is one symptom of arthritis, the pain and stiffness of the joints is particularly debilitating as this physically inhibits activity and lessens the motivation for daily activities, as well as causing sleeplessness, and results in an overall negative impact on the general well-being of an individual, as one susceptible to such pain and joint stiffening must generally refrain from normal daily activities such as walking, entering a vehicle, etc.
    Furthermore, in WO 2014/005597 Al a method is described for providing a dried rose hip powder from rose hip shells which has a high content of e.g. vitamin C. Despite WO 2014/005597 Al describes gentie handling of the rose hip and gentie milling temperatures, below 40°C, it is preferred that synthetic vitamin C is added to the rose hip powder as naturally occurring vitamin C in rose hips Is degraded too fast and may disappears.
    Hence, an improved method for providing a plant material where a high content of the naturally occurring vitamin C (as well as other active ingredients) has been preserved would be advantageous. In particular, there is a need for an improved method for preparing products, formulations or fractions from plant materials, such as rose hips, where the active ingredients, in particular the naturally occurring vitamin C, have been preserved and which method is simple, reproducible and more efficient.
    Summary of the invention
    Thus, an object of the present invention relates to an Improved method for providing a plant material where a high content of the naturally occurring vitamin C (as well as otheractive ingredients) has been preserved.
    In particular, it Is an object of the present invention to provide a method that solves the above-mentioned problems of the prior art with degradation of the naturally occurring vitamin C in order to provide a liquid product from a plant material, such as rose hip, with high preservation of the active ingredients, such as vitamin C, and which method is simple, reproducible and more efficient.
    Thus, one aspect of the invention relates to a method of preparing a plant product comprising at least 0.05% (w/w) vitamin C on a dry-matter basis, the method comprises the steps of:
    (i) providing the plant material;
    DK 2016 71020 A1 (ii) optionally, washing the plant materia! with a washing liquid;
    (iii) freezing the plant material to a temperature below 0°C, providing a frozen plant material;
    (iv) subjecting the frozen plant materia! to a coarsely chopping process, providing a coarsely chopped and frozen plant material;
    (v) subjecting the coarsely chopped and frozen plant material to an aqueous extraction solution, providing a liquid coarsely chopped and chilled plant material;
    (vi) wet grinding the liquid coarsely chopped and chilled plant material, providing the plant product comprising vitamin C;
    wherein the vitamin C present in the plant product is the vitamin C naturally occurring in the plant material.
    Another aspect of the present invention relates to a plant product obtainable by a method according to the present invention.
    An even further aspect of the present invention relates to a plant product a comprising at least 0.05% vitamin C on a dry-matter basis, wherein the vitamin C present in the plant product is the vitamin C naturally occurring in the plant material.
    Yet another aspect of the present invention relates to an ingredient rich in naturally occurring Vitamin C comprising the plant product according to the present invention.
    Still another aspect of the present invention relates to the use of the plant product according to the present invention or the ingredient according to the present invention in a beverage, nutritional beverages, soft drinks, fruit beverages and juices, electrolyte containing beverages, beer, sports beverages, energy beverages, carbonated beverages; or in a food product such as jam; or in a candy.
    Detailed description of the invention
    Accordingly, there is a huge interest in herbal fractions showing various nutritional, medical and/or pharmaceutical activities and extensive efforts has been done to preserved
    DK 2016 71020 A1 the active ingredients. Vitamin C has shown to be particular difficult as it has a tendency easily to degrade. However, the inventors of the present invention, surprisingly found a method for preparing a plant product having the active ingredients., in particular vitamin C, preserved.
    A preferred embodiment of the present invention relates to a method of preparing a plant product comprising at feast 0.05% (w/w) vitamin C on a dry-matter basis, the method comprises the steps of:
    (i) providing the plant materia!;
    (ii) optionally, washing the plant material with a washing liquid;
    (Hi) freezing the plant material to a temperature below 0°C, providing a frozen plant material;
    (iv) subjecting the frozen plant material to a coarsely chopping process, providing a coarsely chopped and frozen plant material;
    (v) subjecting the coarsely chopped and frozen plant material to an aqueous extraction solution, providing a liquid coarsely chopped and chilled plant material;
    (vi) wet grinding the liquid coarsely chopped and chilled plant material, providing the plant product comprising vitamin C;
    wherein the vitamin C present in the plant product is the vitamin C naturally occurring in the plant material.
    The first step (step (i)) of the method according to the present invention relates to providing a plant material. Preferably the plant material may be harvested in any generally known manner when fully ripe.
    In the present context, the term plant material relates to a material that may be obtained from the group consisting of:
    - Kakadu plum, Camu Camu, Acerola, Seabuckthorn, Indian gooseberry, Rose hip, Baobab, Chiii pepper (green), Guava (common, raw), Blackcurrant, Red pepper, Chili pepper (red), Parsley, Kiwifruit, Broccoli, Loganberry, Redcurrant, Brussels sprouts, Wolfberry (Goji), Lychee, Persimmon (native, raw), Cloudberry,
    DK 2016 71020 A1
    Elderberry, Papaya, Strawberry, Orange, Lemon, Pineapple, Cauliflower, Kate, Melon, cantaloupe, Garlic, Grapefruit, Raspberry, Tangerine, Mandarin orange, Passion fruit, Spinach, Cabbage raw green, Lime, Mango, Rutabaga, Blackberry, Potato, Melon, honeydew, Tomato, red, Cranberry, Tomato, Blueberry, Pawpaw, Grape, Apricot, Plurn, Watermelon, Banana, Avocado, Crabapple, Onion, Cherry, Peach, Carrot, Apple, Asparagus, Homed melon, Beetroot, Chokecherry, Pear, Lettuce, Cucumber, Eggplant, Raisin, Fig, and Bilberry,
    In a preferred embodiment of the present invention, the plant material may be a rose-hip material, Preferably the rose-hip material may be selected from the group consisting of Rosa canina (dog rose-hip), Rosa gallica, Rosa condita, Rosa rugosa, Rosa hugonis, Rosa nitida, Rosa pendulina, Rosa pimpinellifolia, and Rosa sericea, Even more preferably, the plant material may be Rosa canina.
    In an embodiment of the present invention the part of the plant material that may be useful is selected from the group consisting of the leaf, the stalk, the fruit, the root or any combination hereof.
    After harvesting, the plant material may optionally be subjected to washing using a washing liquid. The washing may remove extraneous matter not intended to be part of the plant product. In an embodiment of the present invention the temperature of the washing liquid provided in step (il), and during the washing process may be kept below 50°C, such as below 40°C e.g. below 30°C, such as below 25°C e.g. below 20ο0, such as below 15ο0 e.g. below 10°C, such as below 5’C, in order to preserve as much of the active ingredients as possible.
    Preferably the washing liquid may be water.
    When the plant material has been provided and optionally been washed, the plant material may be frozen which preserves the active ingredients, such as vitamin C and/or makes the plant materia! easier to handie and/or avoids the plant material becomes sticky during handling.
    In the present context, the term active ingredients relates in addition to vitamin C one or more of other vitamins, carotenoids and phenolic compounds (including flavonoids).
    In the present context, the term frozen relates to a temperature and pressure combination where the water present in and around the plant material is crystalline. In the
    DK 2016 71020 A1 frozen state the plant material may be considered being dry, even in the presence of crystalline water.
    In an embodiment of the present invention the plant material in step (Hi) Is frozen to, and kept at, a temperature below 0°C, such as to a temperature below -5°C, e.g, to a temperature below 10°C, such as to a temperature below -15°C, e.g. to a temperature below -18°C,
    The frozen plant material may be stored if the further processing in delayed or postponed, for further processing of the frozen plant material may be continues immediately after the plant material has reached the desired temperature.
    Following freezing of the plant material, the frozen plant material may be subjected to a coarsely chopping process and providing a coarsely chopped and frozen plant material. In the present context, the terms ’’coarsely chopped or coarsely chopping relates to a simple opening of the plant material in order to liberate un-desirecl materials (in case of rose hips on-desirable materials may be e.g, seeds, hair, and extraneous matter), which subsequently may be separated from the plant material. In an embodiment of the present invention the coarsely chopping may be done by a knife, e.g. a knife automatically rotating in a chopping chamber.
    After the coarsely chopping the dry-matter content of the coarsely chopped and frozen plant material is 75% (w/w) or less, such as 50% (w/w) or less, e.g. 35% or less, such as 30% (w/w) or less, e.g. 25% or less, such as 20% (w/w) or less, e.g, 15% or less, such as 10% (w/w) or less.
    In an embodiment of the present invention the coarsely chopped and frozen rose hip material Is subjected to a separation process removing hair, seeds and/or ice crystals from the rose hip shell. Hence, the rosehip shells are then continued for further processing in order to provide the plant product (the rosehip product).
    In the context of the present Invention, the terms shell or rosehip shell are used interchangeable and relate to the flesh and the outer coating of the rosehip, where the seeds, hair and stalk has been removed.
    In an embodiment of the present invention the separation process may Involve a sieving mesh allowing the rose hip shell to be retained by the sieving mesh and allowing the hair, seeds and/or ice crystals to pass through the sieving mesh. In an alternative embodiment,
    DK 2016 71020 A1 the separation process may Involve centrifugation of the coarsely chopped and frozen rosehip material separating the rose hip shells from the hair, seeds and/or ice crystals.
    In a further embodiment, of the present invention the sieving mesh may have a mesh size of 4x4 mm or more, such as a mesh size of 5x5 mm or more, e.g. a mesh size of 6x6 mm or more, such as a mesh size of 8x8 mm or more, e.g. a mesh size of 10x10 mm or more. This allows the coarsely chopped and frozen rosehip shells to be retained by the sieving mesh, whereas the hair, seeds and/or ice crystals are smaller in size and therefore allowed to pass through the sieving mesh.
    It is important that the temperature of the frozen plant material as such and during the process of coarsely chopping in step (iv), and/or the coarsely chopped and frozen plant material as such are kept at a low temperature, preferably kept frozen in order to preserve the active ingredients, such as vitamin C; and/or make the plant material easier to handle; and/or avoid the plant to materia! become sticky during handling.
    Hence, the temperature of the frozen plant material during the process of coarsely chopping in step (iv), and/or the coarsely chopped and frozen plant material may be kept at a temperature below 0°C, such as to a temperature below -5 °C, e.g. to a temperature below -10°C, such as to a temperature below -15°C, e.g, to a temperature below -18°C,
    The process of coarsely chopping in step (iv) may preferably be performed on frozen plant material, e.g. rosehip shells, without free-flowing water (hence, only in the presence of crystalline water).
    When the plant material has been coarsely chopped (step (iv)), the the coarsely chopped and frozen plant materia! may be mixed with the aqueous extraction solution in step (v). In the present context, the term aqueous extraction solution relates to a solution comprising water which is capable of solubilizing one or more active ingredients, such as vitamin C, in the water phase from the plant material, such as from the rosehip shells.
    In an embodiment of the present invention the coarsely chopped and frozen plant material may be mixed with an aqueous extraction solution In step (v) at a ratio in the range of 1:99 on a weight/welght basis; such as in the range of 2:98, e.g. in the range of 3:97; such as in the range of 4:96, e.g. in the range of 5:95; such as in the range of 5:94, e.g. in the range of 7:93; such as in the range of 8:92, e.g. In the range of 9:91; such as in the range of 10:90, e.g. in the range of .11:89; such as in the range of 12:88, e.g. in the range of 13:87; such as in the range of 14:86, e.g. in the range of 15:85.
    DK 2016 71020 A1
    In order to liberate more active ingredients from the rosehip material the aqueous extraction solution may further comprises a cell wall degrading enzyme or a mixture of ceil wail degrading enzymes. Preferably, the cell wail degrading enzyme may be one or more enzymes selected from the group consisting of cellulase, ß-glucanase, xylanase, arabanase and pentosanase.
    If a cell wall degrading enzyme or a mixture of ceil wall degrading enzymes has been used, the enzymatic activity may be inactivated by heat, or by addition of an acid or a base.
    In an embodiment of the present invention, the aqueous extraction solution is selected from water; beverages, nutritional beverages, soft drinks, fruit beverages and juices, electrolyte containing beverages, beer, sports beverages, energy beverages, carbonated beverages.
    The temperature of the aqueous extraction solution when added to the coarsely chopped and frozen plant material may preferably be below below 50°C, such as below 40°C e.g. below 30°C, such as below 25°C e.g. below 20°C, such as below 15aC e.g. below 10°C, such as below 5°C.
    When the coarsely chopped and frozen plant material may be subjected to the aqueous extraction solution, the coarsely chopped and frozen plant material starts to thaw and result in a liquid coarsely chopped and chilled plant material. In an embodiment of the present invention the liquid coarsely chopped and chilled plant material has a temperature below 25’C e.g. below 20°C, such as below 15 °C e.g. below 10°C, such as below 5°C, e.g. about 2°C.
    In a further embodiment of the present Invention, the liquid coarsely chopped and chilled plant material provided In step (v) has a dry-matter content of about 15%, e.g. about 12% such as about 10%, e.g. about 8%, such as about 5%, e.g. in the range of 2-15%, such as in the range of 3-12%, e.g. in the range of 4-10%, such as in the range of 5-8%, e.g. in the range of 6-7%.
    The coarsely chopped and frozen plant material may be allowed to thaw in the aqueous extraction solution before subjecting the material to the wet grinding process (step (vi)) of the liquid coarsely chopped and chilled plant material. The advantage of this is that the method becomes more effective and provides Increased content of active ingredients, such as vitamin C, available when the plant material is thawed relative to frozen plant materials.
    DK 2016 71020 A1
    When the liquid coarsely chopped and chllied plant material has been thawed, or during thawing of the coarsely chopped and frozen plant material, the plant material (the liquid coarsely chopped and chilled plant material or the coarsely chopped and frozen plant material) may be subjected to wet grinding. From the wet grinding the plant product may be directly obtained.
    In an embodiment of the present invention, the coarsely chopped and frozen plant material may be subjected to the aqueous extraction solution for a period ranging from 10 seconds to 20 minutes, such as ranging from 30 seconds to 10 minutes, e.g. ranging from 45 seconds to 5 minutes, such as ranging from 1 minute to 2 minutes, e.g. approximately 1 minute before being subjected to subjected to wet grinding, as described in step (v).
    In the present context, the term grinding relates to the process of comminuting the plant material to a fine powder.
    In an embodiment of the present invention, the resulting plant material obtained from the wet grinding process or the plant product comprises a particle size sufficiently small to allow the plant product (or the plant material) to pass a mesh size of 1x1 mm or less, such as 0.9x0.9 mm or less, e.g, 0,7x0,7 mm or less, such as 0.5x0.5 mm or less, e.g. 03x0,3 mm or less.
    In an embodiment of the present invention the temperature during the wet grinding process In step (vi) Is kept at a temperature below 50°C, such as below 40sC e.g. below 30°C, such as beiow 25°C e.g. below 20’C, such as below 15°C e.g. below 10°C, such as below 5°C, e.g. beiow 0’C.
    When marketing a natural product as the plant product according to the present invention, potential harmful organisms should have been destroyed. For this purpose, the plant product according to the present invention may be pasteurized.
    Preferably, the pasteurization process may involve a treatment at a temperature in the range of 70-90°C and a time of pasteurization of up to 50 minutes, such as up to 40 minutes, such as up to 30 minutes, e.g. up to 20 minutes, such as up to 10 minutes, e.g. up to 5 minutes, e.g. up to 4 minutes, such as up to 3 minutes, e.g, up to 2 minutes, such as up to 1 minute. In the present context, the term time of pasteurization relates to the steady state temperature in the range of 70-90°C, It is however also preferred that the temperature increase and the following cooling of the plant product may be a relatively fast procedure, preferably, the temperature increase and the following cooling (preferably to a temperature of 15-20°C) of the plant product may be done individually (the
    DK 2016 71020 A1 temperature increase and the cooling separately) within 30 minutes, more preferabiy within 20 minutes, even more preferabiy within 10 minutes, even more preferably within 5 minutes, even more preferabiy within 4 minutes, even more preferably within 3 minutes.
    It is preferred that the method according to the present invention does not involve a drying step.
    In a preferred embodiment of the present invention, further addition of vitamin C (in particular further addition of synthetic vitamin C) to the plant product is not necessary.
    The method according to the present invention, is highly gentle and may improve the preservation of the active ingredients, such as vitamin C. However, the gentle method according to the present invention may result in the preservation of several other ingredients of the plant material. These other ingredients may be one or more of other vitamins, carotenoids and phenolic compounds (including flavonoids).
    In a preferred embodiment of the present invention the content of vitamin C in the plant product may be at least 0.075% vitamin C (w/w) on a dry-matter basis, such as at least 0.1% vitamin C, e,g. 0.25% vitamin C, such as at least 0.5% vitamin C, e,g. 0.75% vitamin C, such as at least 1,0% vitamin C, e.g, 1.5% vitamin C, such as at least 2.0% vitamin C, e.g. 2.5% vitamin C, such as at least 3.0% vitamin C, e.g. 3.5% vitamin C, such as at least 4.0% vitamin C,
    In an embodiment of the present invention the co-extraction of vitamin C in combination with a glycoside of a mono- or diacyglycerol may be provided. Hence, the plant product comprises a glycoside of a mono- or diacyglycerol, Preferabiy, the plant product comprises vitamin C and a glycoside of a mono- or diacyglycerol.
    In a further embodiment of the present invention, the glycoside of a mono- or dlacyglyceroi may be selected from the group consisting of 3-ß-D-galactopyranosyloxy-2(octadeca-9 Z,12 Z,15 Z-trienoyloxy)propanyi octadeca-9 Z,12 Z,15 Z-trienoate, 3-ß-Dglucopyranosyioxy-2-(octadeca-9 Z,12 Z,15 Z-trienoyloxy)propanyl octadeca-9 Z,12 Z,15 Z-trienoate, 3-O-D-ga!actopyranosyioxy-2-(oct .ideca-9 Z,12 Z,15 Z“trienoyloxy)propanyi actadeca-9 Z,12 Z,15 Z-trienoate, and 3-a-D-glucopyranosyioxy-2-(octadeca-9 Z,12 Z,15 Z-trienoyloxy)propanyi octadeca-9 Z,12 Z,15 Z-trienoate and mixtures hereof,
    In order to preserve the active ingredients of the plant product, such as vitamin C, the plant product may be frozen. In an embodiment of the present invention the plant product may be frozen to, and kept at, a temperature below 0°C, such as to a temperature below
    DK 2016 71020 A1
    5°C, e.g, to a temperature below ~10°C, such as to a temperature below -15°C, e,g. to a temperature below -18°C,
    The inventors of the present invention found that the plant product prepared by the present method was unique in Its composition compared to the plant products provided in prior art. Without being bound by any theory, it is expected that the plant product according to the present invention distinguish from the prior art plant products because of the cold treatment throughout the preparation method which results in a unique profile of the active ingredients.
    A preferred embodiment of the present invention relates to a plant product a comprising at least 0.05% (w/w) vitamin C on a dry-matter basis, wherein the vitamin C present in the plant product is the vitamin C naturally occurring in the plant material.
    In order to preserve as much of the active ingredients, such as vitamin C, as possible no drying of the plant product may be provided, Hence, the plant product according to the present invention Is an aqueous plant product.
    In an embodiment of the present invention the plant product comprises a dry-matter content of about 15%, e.g. about 12% such as about 10%, e.g, about 8%, such as about 5%, e.g, in the range of 2-35%, such as in the range of 3-25%, e.g. in the range of 415%, such as in the range of 5-10%, e.g, in the range of 6-8%,
    For the purpose of improving the extraction of the active ingredients from the plant material and in order to improve the palatabliity of the plant product is pulverized. In an embodiment of the present invention the plant product comprises a particle size allowing the plant product to pass a mesh size of 1x1 mm or less, such as 0,9x0,9 mm or less, e.g. 0.7x0.7 mm or less, such as 0.5x0.5 mm or less, e.g, 0.3x0.3 mm or less.
    Further addition of synthetic vitamin C is not necessary as the content of vitamin C in the plant product provided Is high. Hence, in an embodiment of the present invention the plant product comprises a content of vitamin C in the plant product of at least 0,0753¾ vitamin C (w/w) on a dry-matter basis and relative to the total weight of the plant product, such as at least 0.1% vitamin C, e.g. 0,25% vitamin C, such as at least 0.5% vitamin C, e.g. 0,753¾ vitamin C, such as at least 1.03¾ vitamin C, e.g, 1,5% vitamin C, such as at least 2.0% vitamin C, e.g. 2.5% vitamin C, such as at least 3.0% vitamin C, e.g. 3.5% vitamin C, such as at least 4.0% vitamin C.
    DK 2016 71020 A1
    In addition to the increased content of vitamin C, the plant product further comprises a glycoside of a mono- or diacyglycerol, Preferably, the glycoside of a mono- or diacyglyceroi may be selected from the group consisting of 3-ß-D-galactopyranosyioxy-2-(octadeca-9 Z,12 Z,15 Z-trienoyloxy)propanyl octadeca-9 Z,12 Z,15 Z-trienoate, 3-ß-Dgiucopyranosyioxy-2-(octadeca“9 Z,12 Z,15 Z-trienoyloxy)propanyl octadeca-9 Z,12 2,15 Z-trienoate, 3-a-D-galactopyranosyloxy-2-(octadeca-9 Z,12 Z,15 Z-trienoyloxy)propanyl actadeca-9 Z,12 Z,15 Z-trienoate, and 3-a“D“glucopyranosyloxy-2-(octadeca-9 Z,12 Z,15 Z-trienoyloxy)propanyl octadeca-9 Z,12 Z,15 Z-trienoate and mixtures hereof,
    In a further embodiment of the present invention the plant product comprises a rose-hip material, preferably the rose-hip material is selected from the group consisting of Rosa canina (“dog rose-hip), Rosa gallica, Rosa condita, Rosa rugosa, Rosa hugonis, Rosa nitida, Rosa pendulina, Rosa pimpinellifolia, and Rosa sericea, preferably the plant material is Rosa canina.
    In an even further embodiment of the present invention, the plant product may be a rose hip product, wherein the rose hip product comprises less than 5% rose hip seeds, such as less than 3% rose hip seeds, e.g. less than 1% rose hip seeds, such as being depleted from rose hip seeds.
    The plant product according to the present invention may be used for many different applications either as the product as such (the feed product, the food product, or the beverage) or as an ingredient in several feed products, food products, or beverages. The plant product may be used as an ingredient and constitute a part of the final product such as in a beverage, including nutritional beverages, soft drinks, fruit beverages and juices, electrolyte containing beverages, beer, sports beverages, energy beverages, carbonated beverages; or in a food product such as jam; or in a candy; or in animal feed. The feed product, the food product, or the beverage may form part of the plant product when e.g. the beverage may be used as the aqueous extraction solution. Such aqueous extraction solutions may be a beverage, such as nutritional beverages, soft drinks, fruit beverages and juices, electrolyte containing beverages, beer, sports beverages, energy beverages, carbonated beverages.
    The plant product may be incorporated within or used on many of the foods and beverages consumed on a daily basis. Suitable foods and beverages which could be made, include but are not limited to, nutritional beverages, soft drinks, fruit beverages and juices, electrolyte containing beverages, beer, sports beverages, energy beverages, carbonated beverages, puddings, baked goods (i.e,, cookies, brownies, fudge, cake, breads), non-baked extruded foods (i.e., bars), salad dressings, condiments, confections (i,e., candy), snack foods (i.e,,
    DK 2016 71020 A1 chips, pretzels, tortillas), drips and spreads, ice cream, chewing gum, candies, frozen confections and novelties, dairy products such as yogurt, margarine-like spreads, seasonings such as for meat, poultry, seafood and salads.
    An embodiment of the present invention relates to a medical product comprising the plant product according to the present invention, for use as a medicament.
    A further aspect of the present invention relates to a product comprising the plant product according to the present invention, for use as a medicament which contributes to one or more of the following conditions:
    - maintaining the normal function of the immune system during and after intense physical exercise;
    - normal collagen formation for the normal function of bones
    - normal collagen formation for the norma! function of cartilage
    - normai function of the immune system
    - the protection of cells from oxidative stress
    - the reduction of tiredness and fatigue
    - the regeneration of the reduced form of vitamin E
    - Increased iron absorption
    - normal collagen formation for the norma! function of blood vessels
    - normal collagen formation for the norma! function of gums
    - normal coliagen formation for the normal function of skin
    - normal collagen formation for the normal function of teeth
    - normal energy-yielding metabolism
    - normal functioning of the nervous system
    - normal psychological function
    An even further aspect of the present invention relates to a product comprising the plant product according to the present invention, for use as a medicament for the treatment, the alleviation and/or prevention of inflammatory diseases. Preferably, the inflammatory disease is arthritis and/or osteoarthrosis, more preferred degenerative arthritis.
    A product comprising the plant product may be used for the prevention, treatment or alleviation of inflammation, whether caused by illness or medical conditions, such as viral or bacterial diseases (commonly termed Inflammatory conditions).
    Inflammation“ is defined in Stedman's Medical Dictionary, 26th Edit! on as
    DK 2016 71020 A1 a fundamental pathologic process consisting of a dynamic mixture of cyto/oglcai and chemical reactions that occur in the affected blood vessels and adjacent tissue in response to injury or abnormal stimulation caused by physical, chemical or biological agents, including the local reactions and resulting morphologic changes, the destruction of removal of the injurious material, and the responses that lead to repair and healing.
    Examples of relevant inflammatory conditions are hepatitis, meningitis, rheumatoid arthritis, inflammatory bowl diseases such as Crohn's disease, allergic syndromes, diabetes, congestive heart disease, psoriatic, reactive or osteoarthritis or other arthritides such as osteoarthrosis, multiple sclerosis, atherosclerosis, sepsis/septic shock, dermal inflammation, graft rejection, and inflammation secondary to chemotherapy or radiotherapy of neoplastic disease.
    In an embodiment of the present invention, administration may proceed by oral, buccal, parenteral, topical, rectal, transdermal or intranasal administration. Oral administration may be preferred.
    In the present context, the term mammal is intended to include larger mammals such as humans as well as domestic or farm animals such as horses, dogs, sheep, pigs, cows, etc. Among these mammals, humans are particularly interesting subjects to benefit from the invention.
    It should be noted that embodiments and features described in the context of one of the aspects of the present invention also apply to the other aspects of the Invention.
    All patent and non-patent references cited in the present application, are hereby Incorporated by reference in their entirety.
    The invention will now be described in further details in the following non-limiting exampies.
    Examples
    Example 1
    Preparation of a plant material based on rose hips (Rosa canina) and water
    DK 2016 71020 A1 kg freshiy harvested rose hips (Rosa canina) were washed in 15°C water and frozen to -18°C. The frozen rose hips were coarsely chopped and transferred to a metal filter having a mesh size of 5x5 mm allowing the rose hip seeds, the rose hip hair, the ice crystals, and other extraneous matter to pass through and showing the rose hips sheii to be retained and the rose hip shells may be collected from the top of the separator. The rose hip shells were analysed and showed a dry-matter content of 37% relative to the rose hip shells.
    1.35 kg of the frozen rose hip shells was added 8.65 litre water (8°C warm) resulting in an approximately 5% dry-matter content. The frozen rose hip shells are thawed and subjected to a wet grinding process using a perforated disc mill, FrymaKoruma. After 10 minutes of wet grinding the wet grinded rose hip shells are removed and filtered using a vibrating filter having a mesh size of 500x500 μm. The resulting plant product (rose hip sheii product) runs through the vibrating filter and the solid material retained by the filter is returned to the to the wet grinding process.
    The resulting plant product was analysed and had a vitamin C content of 0.186% which correspond to a dry-matter content of vitamin C of 3.72%.
    The resulting plant product was subjected a pasteurization where it was heated to 80°C over a period of 3 minutes. The temperature was maintained at 80-85C for 3 minutes and then cooled to 20°C over a time period of 3 minutes. The resulting pasteurized plant product was analysed and had a vitamin C content of 0.184% relative to the 0.186% of the un-pasteurized plant product. Hence it is considered that the pasteurization has no effect on the vitamin C content of the product.
    Example 2
    Preparation of an apple juice comprising vitamin C from rose hips (Rosa canina) kg freshly harvested rose hips (Rosa canina) were washed in 15°C water and frozen to -18°C. The frozen rose hips were coarsely chopped and transferred to a metal filter having a mesh size of 5x5 mm allowing the rose hip seeds, the rose hip hair, the ice crystals, and other extraneous matter to pass through and allowing the rose hips shell to be retained and the rose hip shells may be collected from the top of the separator. The rose hip shells were analysed and showed a dry-matter content of 37% relative to the rose hip shells.
    0.8 kg of the frozen rose hip shells was added 9.2 litre apple juice (15°C warm) resulting in an approximately 3% dry-matter content from rose hips. The frozen rose hip shells are thawed in the apple juice and subjected to a wet grinding process for about 10 minutes using a perforated disc mill, FrymaKoruma.
    DK 2016 71020 A1
    The resulting apple juice comprising the plant product (the wet grinded rose hip shells) was analysed and had a vitamin C content of 0.11%.
    The resulting appie juice was subjected pasteurization where it was heated to 80°C over a period of 3 minutes. The temperature was maintained at 80-85°C for 3 minutes and then cooled to 20°C over a time period of 3 minutes.
    The invention wii! now be defined in the foilowing item:
    Items
    1. A method of preparing a plant product comprising at least 0.05% (w/w) vitamin C on a dry-matter basis, the method comprises the steps of:
    (I) providing the plant material;
    (ii) optionally, washing the plant material with a washing liquid;
    (Hi) freezing the plant material to a temperature below 0°C, providing a frozen plant material;
    (iv) subjecting the frozen plant material to a coarsely chopping process, providing a coarsely chopped and frozen plant material;
    (v) subjecting the coarsely chopped and frozen plant material to an aqueous extraction solution, providing a liquid coarsely chopped and chilled plant material;
    (vi) wet grinding the liquid coarsely chopped and chilled plant material, providing the plant product comprising vitamin C;
    wherein the vitamin C present in the plant product is the vitamin C naturally occurring in the plant material.
    2. The method according to item 1, wherein the plant material is a rose-hip material, preferably the rose-hip material Is selected from the group consisting of Rosa canina (dog rose-hip), Rosa gallica, Rosa condita, Rosa rugosa, Rosa hugonis, Rosa nitida, Rosa
    DK 2016 71020 A1 pendulina, Rosa pimpinellifolia, and Rosa sericea, preferably the plant material is Rosa canina.
    3. The method according to anyone of items 1 or 2, wherein the plant product comprises a glycoside of a mono- or diacyglycerol,
    4. The method according to item 3, wherein the glycoside of a mono- or diacyglycerol is selected from the group consisting of 3-ß-D-gaiactopyranosyloxy-2--(octadeca-9 Z,12 Z,15 Z-trienoyioxy)propanyl octadeca-9 2,12 Z,15 Z-trienoate, 3-ß-D-glucopyranosyloxy-2- (octadeca-9 Z,12 Z,15 Z-trienoyloxy Jpropanyl octadeca-9 Z,12 Z,15 Z-trienoate, 3-o-Dgalactopyranosyloxy-2-(octadeca-9 Z,12 Z,15 Z-trienoyloxy)propanyi actadeca-9 Z,12 Z,15 Z-trienoate, and 3-o-D-glucopyranosy!oxy-2-(octadeca-9 Z,12 Z,15 Ztrienoyloxy)propanyl octadeca-9 Z,12 Z,15 Z-trienoate and mixtures hereof,
    5. The method according to anyone of items 2-4, wherein the coarsely chopped and frozen rose hip material is subjected to a separation process removing hair, seeds and/or ice crystals from the rose hip shell
    6. The method according to item 5, wherein the separation process involves a sieving mesh allowing the rose hip shell to be retained by the sieving mesh and allowing the hair, seeds and/or ice crystals to pass through the sieving mesh,
    7. The method according to item 6, wherein the sieving mesh has a mesh size of 4x4 mm or more, such as a mesh size of 5x5 mm or more, e.g, a mesh size of 6x6 mm or more, such as a mesh size of 8x8 mm or more, e.g. a mesh size of 10x 10 mm or more.
    8. The method according to anyone of the preceding items, wherein the plant product comprises a particle size allowing the plant product to pass a mesh size of 1 x 1 mm or less, such as 0,9x0.9 mm or less, e.g, 0,7x0.7 mm or less, such as 0.5x0.5 mm or less, e.g. 0,3x0.3 mm or less.
    9. The method according to anyone of the preceding items, wherein the content of vitamin C in the plant product is at ieast 0.075% vitamin C (w/w) on a dry-matter basis and relative to the total weight of the plant product, such as at least 0.1% vitamin C, e.g. 0,25% vitamin C, such as at least 0.5% vitamin C, e.g, 0,75% vitamin C, such as at least 1.0% vitamin C, e.g. 1.5% vitamin C, such as at ieast 2.0% vitamin C, e.g, 2,5% vitamin C, such as at least 3.0% vitamin C, e.g. 3,5% vitamin C, such as at least 4,0% vitamin C.
    DK 2016 71020 A1
    10. The method according to anyone of the preceding items wherein the plant product is pasteurized.
    11. The method according to items 10, wherein the pasteurizing process involves a treatment at a temperature in the range of 70-90°C and a time of pasteurization of up to 50 minutes, such as up to 40 minutes, such as up to 30 minutes, e.g. up to 20 minutes, such as up to 10 minutes, e.g. up to 5 minutes, e.g. up to 4 minutes, such as up to 3 minutes, e.g. up to 2 minutes, such as up to 1 minute.
    12. The method according to anyone of the preceding items, wherein the liquid coarsely' chopped and chilled plant material provided in step (v) has a dry-matter content of about 15%, e.g. about 12% such as about 10%, e.g. about 8%, such as about 5%, e.g, in the range of 2-15%, such as in the range of 3-12%, e.g, tn the range of 4-10%, such as in the range of 5-8%, e.g. in the range of 6-7%,
    13. The method according to anyone of the preceding items, wherein the coarsely chopped and frozen plant material Is mixed with the aqueous extraction solution in step (v) at a ratio in the range of 1:99 on a welght/weight basis; such as in the range of 2:98, e.g. in the range of 3:97; such as in the range of 4:96, e.g. in the range of 5:95; such as in the range of 6:94, e.g. in the range of 7:93; such as In the range of 8:92, e.g. in the range of 9:91; such as in the range of 10:90, e.g. in the range of 11:89; such as in the range of 12:88, e.g. in the range of 13:87; such as In the range of 14:86, e.g. In the range of 15:85.
    14. The method according to anyone of the preceding items, wherein the aqueous extraction solution further comprises a cell wail degrading enzyme or a mixture of ceil wall degrading enzymes,
    15. The method according to Item 15, wherein the ceil wall degrading enzyme is one or more enzymes selected from the group consisting of cellulase, ß-giucanase, xylanase, arabanase and pentosanase.
    16. The method according to anyone of items 14 or 15, wherein the enzymatic activity is inactivated by heat, or by addition of an acid or a base.
    17. The method according to anyone of the preceding items, wherein the washing liquid provided in step (ii), and during the washing process is kept below 50°C, such as below 40^0 e.g. below 30°C, such as below 25°C e.g, below 20°C, such as below 15°C e.g. below 10°C, such as below 5°C.
    DK 2016 71020 A1
    18. The method according to anyone of the preceding items, wherein further addition of vitamin C to the plant product is not necessary.
    19. The method according to anyone of the preceding items, wherein the plant material in step (iii) is frozen to a temperature below 0°C, such as to a temperature below -5°C, e.g. to a temperature below -10°C, such as to a temperature below -15”C, e.g. to a temperature below -18°C.
    20. The method according to anyone of the preceding items, wherein the frozen plant material in step (iii) is kept at a temperature below 0°C, such as to a temperature below 5'C, e.g. to a temperature below -10°C, such as to a temperature below -15°C, e.g. to a temperature below -18aC.
    21. The method according to anyone of the preceding items, wherein the temperature of the frozen plant material during the process of coarsely chopping in step (iv), and/or the coarsely chopped and frozen plant material is kept at a temperature below CTC, such as to a temperature below -5°C, e.g. to a temperature below -10°C, such as to a temperature below ~15°C, e.g. to a temperature below -18°C.
    22. The method according to anyone of items 6-23, wherein the temperature of the coarsely chopped and frozen rose hip material during the separation process, and/or the the rose hip shells are kept at a temperature below 0°C, such as to a temperature below 5aC, e.g, to a temperature below -10’C, such as to a temperature below -15°C, e.g. to a temperature below -18°C.
    23. The method according to anyone of the preceding items, wherein the aqueous extraction solution is selected from water; beverages, nutritional beverages, soft drinks, fruit beverages and juices, electrolyte containing beverages, beer, sports beverages, energy beverages, carbonated beverages,
    24. The method according to anyone of the preceding items, wherein the temperature during the wet grinding process in step (vi) is kept at a temperature beiow 50°C, such as below 40°C e.g, beiow 30°C, such as beiow 25°C e.g. below 20°C, such as beiow 15aC e.g. below 10°C, such as below 5°C, e.g. beiow 0°C.
    25. The method according to anyone of the preceding items, wherein the piant product is frozen to a temperature below 0°C, such as to a temperature below -5°C, e.g. to a
    DK 2016 71020 A1 temperature below -10°C, such as to a temperature below -15°C, e.g. to a temperature below -18°C.
    26. A plant product obtainable by a method according to anyone of Items 1-25.
    27. A plant product a comprising at least 0.05% (w/w) vitamin C on a dry-matter basis, wherein the vitamin C present in the plant product is the vitamin C naturally occurring in the plant material.
    28. The plant product according to anyone of items 26 or 27, wherein the plant product comprises a dry-matter content of about 15%, e.g. about 12% such as about 10%, e.g. about 8%, such as about 5%, e.g. in the range of 2-35%, such as in the range of 3-25%, e.g. in the range of 4-15%, such as in the range of 5-10%, e.g. in the range of 6-8%,
    29. The plant product according to anyone of items 26-28, wherein the plant product comprises a particle size allowing the plant product to pass a mesh size of 1x1 mm or less, such as 0.9x0.9 mm or less, e.g. 0.7x0.7 mm or less, such as 0.5x0,5 mm or less, e.g. 0,3xö,3 mm or less.
    30. The plant product according to anyone of Items 26-29, wherein the plant product comprises a content of vitamin C in the plant product is at least 0.075% vitamin C (w/w) on a dry-matter basis and relative to the total weight of the plant product, such as at least 0.1% vitamin C, e.g. 0.25% vitamin C, such as at least 0.5% vitamin C, e.g. 0.75% vitamin C, such as at least 1.0% vitamin C, e.g. 1.5% vitamin C, such as at least 2.0% vitamin C, e.g. 2.5% vitamin C, such as at least 3.0% vitamin C, e.g. 3.5% vitamin C, such as at least 4.0% vitamin C,
    31. The plant product according to anyone of items 26-30, wherein the plant product further comprises a glycoside of a mono- or diacygiyceroi.
    32. The plant product according to anyone of items 26-31, wherein the plant product comprises a glycoside of a mono- or diacygiyceroi, and wherein the glycoside of a monoor diacygiyceroi is selected from the group consisting of 3-ß-D-galactopyranosyioxy-2(octadeca-9 Z,12 Z,15 Z-trienoyloxy)propanyl octadeca-9 Z,12 Z,15 Z-trienoate, 3-ß-Dgiucopyranosyioxy-2-(octadeca-9 Z,12 Z,15 Z-trienoyloxy)propanyl octadeca-9 Z,12 Z,15 Z-trienoate, S-o-D-gaiactopyranosyioxy-Z-foctadeca-S Z,12 Z,15 Z-trienoyloxy)propanyl actadeca-9 Z,12 Z,15 Z-trienoate, and 3-a-D-glucopyranosyloxy-2-(octadeca-9 Z,12 Z,15 Z-trienoyioxy)propanyi octadeca-9 Z,12 Z,15 Z-trienoate and mixtures hereof.
    DK 2016 71020 A1
    33. The plant product according to anyone of sterns 26-32, wherein the plant product comprises a rose-hip material, preferably the rose-hip material is selected from the group consisting of Rosa canina (“dog rose-hip), Rosa gallica, Rosa conclita, Rosa rugosa, Rosa hugonis, Rosa nitida, Rosa pendulina, Rosa pimpinellifolia, and Rosa sericea, preferably the plant material is Rosa canina.
    34. The plant product according to anyone of items 26-33, wherein the plant product is an ingredient,
    35. A product comprising the plant product according to anyone of items 26-34, for use as a medicament
    36. A product comprising the plant product according to anyone of items 26-35, for use as a medicament for the treatment, the alleviation and/or prevention of inflammatory diseases.
    37. The product according to item 36, wherein the inflammatory disease is arthritis, more preferred degenerative arthritis
    38. An ingredient rich in naturally occurring Vitamin C comprising the plant product according to anyone of items 26-37.
    39. Use of the plant product according to anyone of items 26-37 or the ingredient according to item 39 in a beverage, nutritional beverages, soft drinks, fruit beverages and juices, electrolyte containing beverages, beer, sports beverages, energy beverages, carbonated beverages.; or in a food product such as jam; or in a candy.
    References
    US 6,024,960
    WO 2003/043613
    WO 2014/005597
    DK 2016 71020 A1
    权利要求:
    Claims (10)
    [1] Claims
    1. A method of preparing a plant product comprising at least 0.05% (w/w) vitamin C on a dry-matter basis, the method comprises the steps of:
    (i) providing the plant material;
    (ii) optionally, washing the plant material with a washing liquid;
    (iii) freezing the plant material to a temperature below 0oC, providing a frozen plant material;
    (iv) subjecting the frozen plant material to a coarsely chopping process, providing a coarsely chopped and frozen plant material;
    (v) subjecting the coarsely chopped and frozen plant material to an aqueous extraction solution, providing a liquid coarsely chopped and chilled plant material;
    (vi) wet grinding the liquid coarsely chopped and chilled plant material, providing the plant product comprising vitamin C;
    wherein the vitamin C present in the plant product Is the vitamin C naturally occurring In the plant material.
    [2] 2. The method according to claim 1, wherein the plant material is a rose-hip material, preferably the rose-hip material is selected from the group consisting of Rosa canina (dog rose-hip), Rosa gallica, Rosa condita, Rosa rugosa, Rosa hugonis, Rosa nitida, Rosa penduiina, Rosa pimpinelltfolia, and Rosa sericea, preferably the plant material is Rosa canina.
    [3] 3. The method according to anyone of claims 1 or 2, wherein the coarsely chopped and frozen rose hip material is subjected to a separation process removing hair, seeds and/or Ice crystals from the rose hip shell.
    [4] 4. The method according to anyone of the preceding claims, wherein the frozen plant material in step (iii); the temperature of the coarsely chopped and frozen rose hip material during the separation process, and/or the the rose hip shells; the temperature of the frozen plant material during the process of coarsely chopping in step (iv), and/or the
    DK 2016 71020 A1 coarsely chopped and frozen plant material is kept at a temperature below 0°C, such as to a temperature below -5°C, e.g, to a temperature below -10°C, such as to a temperature below -15°C, e.g. to a temperature below -18°C.
    [5] 5. The method according to anyone of the preceding claims, wherein the aqueous extraction solution is selected from water; beverages, nutritional beverages, soft drinks, fruit beverages and juices, electrolyte containing beverages, beer, sports beverages, energy beverages, carbonated beverages,
    [6] 6. The method according to anyone of the preceding claims, wherein the temperature during the wet grinding process in step (vi) is kept at a temperature below 50°C, such as below 40° C e.g. below 30°C, such as below 25°C e.g. below 20°C, such as below 15°C e.g. below 10°C, such as below 5°C, e.g. below 0aC,
    [7] 7. A plant product a comprising at least 0.05% (w/w) vitamin C on a dry-matter basis, wherein the vitamin C present in the plant product is the vitamin C naturally occurring in the plant material.
    [8] 8. The plant product according to claim 7, wherein the plant product comprises a particle size allowing the plant product to pass a mesh size of 1x1 mm or less, such as 0,9x0.9 mm or less, e.g. 0.7x0,7 mm or less, such as 0.5x0.5 mm or less, e.g. 0,3x0.3 mm or less,
    [9] 9. The plant product according to anyone of claims 7-8, wherein the plant product comprises a rose-hip material, preferably the rose-hip material is selected from the group consisting of Rosa canina (dog rose-hip), Rosa gallica, Rosa condita, Rosa rugosa, Rosa hugonis, Rosa nitida, Rosa penduiina, Rosa pimpinelilfolia, and Rosa sericea, preferably the plant materia! is Rosa canina.
    [10] 10. Use of the plant product according to anyone of claims 7-9 in a beverage, nutritional beverages, soft drinks, fruit beverages and juices, electrolyte containing beverages, beer, sports beverages, energy beverages, carbonated beverages; or in a food product such as jam; or in a candy.
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    同族专利:
    公开号 | 公开日
    DK179799B1|2019-06-26|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    法律状态:
    2018-08-03| PAT| Application published|Effective date: 20180623 |
    2019-06-26| PME| Patent granted|Effective date: 20190626 |
    优先权:
    申请号 | 申请日 | 专利标题
    DKPA201671020A|DK179799B1|2016-12-22|2016-12-22|Method for preparing a product comprising high amount of naturally occuring vitamin c|DKPA201671020A| DK179799B1|2016-12-22|2016-12-22|Method for preparing a product comprising high amount of naturally occuring vitamin c|
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