瑞士专利CH708531B1 Intervertebral fusion cage.

专利PDF首页>>瑞士专利

专利附录

专利说明

权利要求

类似技术

同族专利

引用文献

法律状态

优先权

专利摘要:
The present invention relates to a cage (1) which is inserted between vertebral bodies of a cervical vertebra or spine during an operation for the treatment of cervical disc disease, myelosis, or a fracture of a cervical vertebra. the cervical vertebra or spine, and more particularly, to a cage with anchors, comprising upper (20) and lower (30) anchors which are attached to a clip (50) inserted into a main body (10) of the cage, deployed upwards and downwards from the main body (10), and locked to the vertebral bodies of a cervical vertebra or vertebral column positioned above and below the cage (1) so that the cage (1) is fixed and locked between the vertebral bodies. The invention also relates to a tool for inserting the clip (50) into the main body (10).
公开号:CH708531B1
申请号:CH01377/14
申请日:2014-09-11
公开日:2019-05-15
发明作者:Kim Seo-Kon；Kim Il
申请人:Ldr Medical S A S；
IPC主号:

专利说明:

Description
Reference to previous applications This application claims the benefit of Korean patent application No. 10-2013-108 840, filed on September 11, 2013 with the Korean Intellectual Property Office, which is inserted here by reference in its entirety.
Background of the invention
1. Field of the Invention The present invention relates to a cage which is inserted between two vertebral bodies of the cervical vertebrae or the spine during an operation for the treatment of cervical disc disease, myelosis, or a fracture of the cervical vertebra or spine, and more particularly, it relates to a cage including upper and lower anchors which are attached to a clip inserted into a main body of the cage, deployed to protrude from the top and bottom of the main body, and locked to the vertebral bodies of the cervical vertebrae or the spinal column which are located above and below the cage so that the cage is fixed between the vertebral bodies.
2. Description of the Prior Art [0003] In general, an operation of inserting an artificial compensation chain cage between two vertebral bodies of the cervical vertebrae or the spine is carried out to treat a cervical disc disease, myelosis, or a fracture of the cervical vertebra or spine in the orthopedic surgery department or in the neurosurgery department. More specifically, a surgeon removes a cervical disc from the diseased area to eliminate nerve compression and inserts the artificial compensation cage to restore and maintain the gap in the area in which the cervical disc has been removed.
[0004] Such a cage is capable of moving in the intervertebral space by the tension applied when the patient is moving. Therefore, an additional unit must be provided to prevent the pivoting of the cage while preventing the movement of the cervical vertebra or the spine in the intervertebral space.
According to the published Korean application No. 10-2011-33707 which disclosed a device for fusing the bodies of the cervical vertebrae, the Korean patent No. 900 991 which disclosed a cage for a vertebral implant, and the published Korean application No. 10-2011-11 049 which disclosed a fusion cage between two vertebral bodies a cage is inserted in the area in which an intervertebral disc has been removed and a reinforcement plate with a predetermined length is attached to the cervical vertebra or the spine by a screw, thereby preventing the displacement of the inserted cage.
In the techniques described above, however, the reinforcing plate is fixed to the front of the cage by the screw. So the head of the screw inserted into the plate or part of the plate can protrude more than protruding parts of the cervical vertebra or spine, which are positioned at the top and bottom of the area in which the disc intervertebral was removed and in which the cage is installed. In this case, depending on the force applied when a patient is moving over time, the cage can be moved or rotated in the intervertebral space so that the head of the screw protrudes into the intervertebral space and enters contact with blood or nervous tissue passing through the cervical vertebra or the spine. So there is a demand for the development of a more stable cage.
In addition, the plate and wash are used to fix lacing. In this case, it is extremely difficult to fix the plate by the screw in such a small intervertebral space, when a lot of attention is required. Therefore, special technical skills are required by a surgeon.
Summary of the Invention Therefore, the present invention has been made to solve the above-mentioned problems of the prior art, and it is an object of the present invention to provide a cage with anchors which is capable to prevent the occurrence of a protruding part of a screw to minimize interference with blood tissue or nerve tissue passing through the cervical vertebra or spine when the cage is placed and performing a fixation procedure cage in a relatively simple and practical way, thereby improving the stability of the operation.
To accomplish the above object, the present invention provides a cage with anchors which includes upper and lower anchors which are attached to a clip inserted into a main body of the cage, deployed upward and outward. low from the main body, and locked to the vertebral bodies of a cervical vertebra or a spine positioned above and below the cage so that the cage is fixed and locked between the vertebral bodies.
The cage according to the present invention has the following effects.
CH 708 531 B1 First, the cage is locked and fixed between two vertebral bodies of a cervical vertebra or a spinal column in the area in which an intervertebral disc has been removed, by the anchors deployed upwards and down from the main body of the cage. Therefore, it is possible to significantly reduce the possibility that a screw for fixing the cage or part of a plate will interfere with the nervous tissue or blood tissue passing through the cervical vertebra or the spine in the area in which the intervertebral disc has been removed and in which the cage is installed. In addition, the prognosis of a patient who has had an intervertebral disc operation can be improved.
In addition, the cage according to the present invention does not use a plate or screw unlike conventional cages, but it includes anchors. Therefore, it is possible to omit a complicated operation of fixing a plate by a screw in a small intervertebral space as in the prior art. Therefore, the convenience of the procedure can be improved and the operation process can be simplified to provide the stability of the operation.
Brief Description of the Drawings The above objects and other objects, characteristics and advantages of the present invention will become apparent from the following detailed description of the preferred exemplary embodiments of the invention together with the accompanying drawings, among which:
fig. 1 is a perspective view of a cage according to a preferred embodiment of the present invention; fig. 2 is a plan view of the cage in accordance with a preferred embodiment of the present invention; fig. 3 is a sectional view taken along line A-A 'of FIG. 2; fig. 4 is an exploded perspective view of the cage in accordance with a preferred embodiment of the present invention; fig. 5a to 5d are detailed diagrams of a main body of the cage in accordance with a preferred embodiment of the present invention; fig. 6a to 6c are detailed diagrams of a top anchor of the cage in accordance with a preferred embodiment of the present invention; fig. 7a to 7c are detailed diagrams of a lower anchor of the cage in accordance with a preferred embodiment of the present invention; Figs. 8A to 8d are detailed diagrams of a clip of the cage in accordance with a preferred embodiment of the present invention; fig. 9 and 10 are diagrams illustrating a state in which the upper and lower anchors of the cage according to a preferred embodiment of the present invention are coupled to the clip; fig. 11a to 11c are detailed diagrams of a cage guiding device in accordance with a preferred embodiment of the present invention; fig. 12a to 12d are diagrams illustrating the state of operation of the cage in accordance with a preferred embodiment of the present invention; fig. 13a to 13c illustrate an insertion mechanism for inserting the cage in accordance with a preferred embodiment of the present invention; and fig. 14 is a diagram illustrating a state in which the cage according to a preferred embodiment of the present invention is placed.
[Explanation of reference signs] 1: cage, 10: main body, 101: upper surface, 102: lateral surface, 103: front surface, 104: lower surface, 105: rear surface, 110: cavity bone fusion, 101 a, 104a: sawtooth protrusions, 120: insertion hole, 130: channel, 140: inclined part, 141: inclined upper surface, 142: flat upper surface, 143: inclined lower surface, 144 : flat lower surface, 145: internal wall surfaces, 146: protrusion surface, 151: mounting grooves, 152: upper wall, 153: lower wall, 154: side wall, 20: upper anchor, 21: upper blade, 22 , 23: upper anchor arm, 24.25: mounting holes, 30: lower anchor, 31: lower blade, 32.33: lower anchor arm, 34.35: mounting holes, 40: guide device , 41: front plate, 42: left bar, 43: right bar,
CH 708 531 B1
44: hole, 45: entry hole, 46: insertion hole, 50: clip, 51: right retaining jaw, 52: left retaining jaw, 53: right side, 54: left side, 55: bottom side , 56: hole, 57: base, 60: guide pin, 61: clip pin, 200: insertion mechanism, 210: head, 211: left head, 212: right head, 213: upper head, 220 : first lower support rod, 221: push button guide, 230: second lower support rod, 240: push button, 241: push plate, 242: rod body, 243: hump, 244: coupling element, 250 : upper support rod, 251: upper guide support rod, 252: support body, D1: upper vertebral body, D2: lower vertebral body
Description of the Preferred Embodiments [0016] Exemplary embodiments of the present invention will be described below in more detail with reference to the accompanying drawings. The present invention can, however, be embodied in different forms and should not be considered as limited to the embodiments highlighted here. Rather, these embodiments are intended for this disclosure to be complete and exhaustive, and will fully convey the scope of the present invention to those skilled in the art. Throughout the description, the same reference numbers refer to the same parts in all the different figures and all the embodiments of the present invention.
The drawings are intended as examples to communicate the idea of the present invention to the skilled person. Therefore, the present invention is not limited to the drawings, but can be embodied in other forms.
In addition, as long as the terms used in this description are not defined differently, the terms have meanings which are typically understood by those skilled in the art to which the present invention relates. In addition, detailed descriptions relating to well known functions or configurations will be excluded so as not to unnecessarily hinder subjects of the present invention.
[0019] FIG. 1 is a perspective view of a cage according to a preferred embodiment of the present invention. Fig. 2 is a plan view of the cage in accordance with an embodiment of the present invention. Fig. 3 is a sectional view taken along line A-A 'of fig. 2.
Referring to Figs. 1 to 3, the cage 1 according to an embodiment of the present invention comprises a main body 10, a clip 50, upper and lower anchors 20 and 30, and a guide device 40. The clip 50 is inserted in the main body 10. The upper and lower anchors 20 and 30 are coupled to the clip 50 and deployed to project upwards and downwards by the insertion of the clip 50. The guide device 40 is coupled to the main body 10 to guide the insertion of the clip 50.
The upper and lower anchors 20 and 30 deployed upwards and downwards from the main body 10 are locked to the upper and lower vertebral bodies of a cervical vertebra or of a vertebral column positioned above and below the cage 1 so that the cage 1 is fixed and locked between the vertebral bodies of the cervical vertebra or the spinal column.
The main body 10 of lacing 1 has a hexahedral shape comprising an upper surface 101, two side surfaces 102, a front surface 103, a lower surface 104, and a rear surface 105. The corners of the main body 10 are rounded.
As illustrated in figs. 2 and 4, the main body 10 includes a bone fusion cavity 110 located between the upper and lower surfaces 101 and 104 and a channel 130 formed therein. The channel 130 corresponds to a space with an opening through which the clip 50 is inserted into the main lacing body 10 from the front surface 103.
In addition, the main body 10 includes an inclined portion 140 formed therein. The inclined portion 140 guides the movement of the upper and lower anchors 20 and 30 when the upper and lower anchors 20 and 30 coupled to the clip 50 inserted through the channel 130 are deployed up and down. The top of the inclined part 140 is open to deploy the upper and lower anchors 20 and 30 towards the outside of the main body 10. The inclined part 140 will be described in more detail below.
As illustrated in fig. 3, the main body 10 includes sawtooth protrusions 101a and 104a formed on its upper and lower surfaces 101 and 104. When the cage 1 is inserted between two vertebral bodies of a cervical vertebra or a spine, the sawtooth protrusions 101a and 104a improve the contact between the upper and lower vertebral bodies.
[0026] FIG. 4 is an exploded perspective view of the cage in accordance with a preferred embodiment of the present invention.
As illustrated in fig. 4, the guide device 40 is coupled to the front surface 103 of the main body 10.
The guide device 40 includes left and right bars 42 and 43 which are formed in its left and right sides and which are inserted into mounting grooves 151 formed in the left and right side surfaces 102 of the main body 10, respectively, and a pin 60 is passed through the holes 44 which are formed in the left and right bars 42 and 43 of the guide device 40 and an insertion hole 120 which is formed through the right side surface 102 from the surface left side 102 of the main body 10. Therefore, the main body 10 and the guide device 40 are coupled to each other.
CH 708 531 B1 After the main body 10 and the guide device 40 are coupled, the clip 50 coupled to the upper and lower anchor 20 and 30 is inserted into the main body 10 through an inlet hole 46 of the device guide 40.
Then, the upper and lower anchors 20 and 30 coupled to the clip 50 are guided along the inclined upper and lower surfaces 141 and 143 of the inclined part 140 formed in the main body 10, and deployed to project upwards. and down from the main body 10 by moving up and down.
At this time, the upper and lower anchors 20 and 30 are coupled to the clip 50 by the pin 61.
Hereinafter, the respective elements of the cage 1 in accordance with a preferred embodiment of the present invention will be described in detail.
Figs. 5a to 5d are detailed diagrams of the main body of the cage in accordance with a preferred embodiment of the present invention. Fig. 5a is a plan view, FIG. 5b is a side view, FIG. 5c is a sectional view taken along line B-B 'of FIG. 5a, and fig. 5d is a front view.
As described above, the main body 10 of the cage 1 is formed with a hexahedral shape comprising the upper surface 101, two lateral surfaces 102, the front surface 103, the lower surface 104, and the rear surface 105, the bone fusion cavity 110 located between the upper and lower surfaces 101 and 104, and the channel 130 providing a space so that the clip 50 can be inserted from the front surface 103 of the main body 10 and fixed to the central part main body 10.
When the upper and lower anchors 20 and 30 coupled to the clip 50 inserted through the channel 130 are deployed up and down, the inclined part 140 formed in the main body 10 guides the movement of the upper and lower anchors 20 and 30. The top and bottom of the inclined part 140 are open to allow the deployment of the upper and lower anchors 20 and 30 towards the outside of the main body 10.
The inclined portion 140 includes an inclined upper surface 141 formed to guide the upward movement of the upper anchor 20, and a planar upper surface 142 which is formed at one end of the upper inclined surface 141.
In addition, the inclined portion 140 comprises an inclined lower surface 143 formed to guide the downward movement of the lower anchor 30, and a flat rear surface 142 which is formed at one end of the inclined lower surface 143.
In addition, a protrusion surface 146 with a predetermined width is formed at the connection between the inclined upper and lower surfaces 141 and 142 of the inclined part 140, and an inner wall surface of the base 57 of the clip 50 is locked to the protuberance surface 146 to stop the insertion of the clip 50 into the channel 130.
The inclined part 140 comprises internal wall surfaces 145 formed on the left and right side surfaces so as to form a step with respect to the upper and lower surfaces 101 and 104 of the main body 10.
The mounting grooves 151 are formed outside the respective internal wall surfaces 145 so that the left and right bars 42 and 43 of the guide device 40 are mounted in the mounting grooves 151. The groove of mounting 151 corresponds to a space formed on the lateral surface 102 of the main body 10 and comprises an upper wall 152, a lower wall 153, and a side wall 154.
The main body 10 of the cage 1 in accordance with a preferred embodiment of the present invention is formed from metal or a metal alloy such as titanium, zirconium, zirconium oxide, hafnium, platinum, rhodium, niobium, steel stainless for surgery, chromium-cobalt steel (CoCr), tantalum or a polymer material such as reinforced plastic or polyether-ether-ketone (PEEK). In addition, a metal such as aluminum, medical steel, or gold can be added to the metal alloy.
Desirably, the polyether-ether-ketone (PEEK) having excellent machinability and durability can be used as the material of the main body 10.
The bone fusion cavity 110 formed in the body 10 can be filled with bone debris extracted from the patient's ilium for the cage placement operation 1. The bone debris stored in the cavity of 110 bone fusion can grow through the cage as time passes after the operation, thereby fusing the intervertebral disc from the diseased area to the cervical vertebra or the spine.
The insertion hole 120 is formed in the left and right surfaces 102 of the main body 10, to fix the pin 60 to couple the guide device 40 to the main body 10.
Figs. 6a to 6c are detailed diagrams of the upper anchor of the cage in accordance with a preferred embodiment of the present invention. Figs. 7a to 7c are detailed diagrams of the lower anchor of the cage in accordance with a preferred embodiment of the present invention. Figs. 8a to 8d are detailed diagrams of the clip of the cage in accordance with a preferred embodiment of the present invention.
Referring to Figs. 6a to 6c, the upper anchor 20 coupled to the clip 50 of the cage 1 comprises an upper blade 21, arms 22 and 23, and mounting holes 24 and 25. The blade 21 has a pointed end surface formed at its end. The arms 22 and 23 are formed on both sides of the upper blade 21 so as to be extended and inclined
CH 708 531 B1 down. The mounting holes 24 and 25 are formed at the ends of the respective arms 22 and 23 in such a way that the pin 61 for coupling the clip 50 can be inserted into the mounting holes 24 and 25.
The upper anchor 20 has a structure inclined upward at an angle which increases from the mounting holes 24 and 25. Therefore, when the cage 1 according to a preferred embodiment of the present invention is inserted between two upper and lower vertebral bodies of a cervical vertebra or spine, the pointed end surface of the upper blade 21 formed at an increasing angle is put into the upper vertebral body and locked to the upper vertebral body in such a way that the cage 1 can be inserted reliably.
Referring to Figs. 7a to 7c, the lower anchor 30 coupled to the clip 50 of the cage 1 comprises a lower blade 31, arms 32 and 33, and mounting holes 34 and 35, like the upper anchor 20. The lower blade 31 is formed at one end of the lower anchor 30 and has a pointed end surface. The arms 32 and 33 are formed on both sides of the lower blade 31 so as to be inclined and extended upwards. The mounting holes 34 and 35 are formed at the ends of the respective arms 32 and 33 in such a way that the pin 61 for coupling the clip 50 can be inserted into the mounting holes 34 and 35.
The lower anchor 30 has a structure inclined downward at an angle which decreases from the mounting holes 34 and 35. Therefore, when the cage 1 according to a preferred embodiment of the present invention is inserted between two upper and lower vertebral bodies of the cervical vertebra or spine, the pointed end surface of the lower blade 31 formed at a decreasing angle is put into the lower vertebral body and locked towards the lower vertebral body in such a way that the cage 1 can be reliably inserted into the upper tip 20.
Referring to Figs. 8a to 8d, the clip 50 for coupling the upper and lower anchors 20 and 30 of the cage 1 comprises right and left clamping jaws 51 and 52 and right and left ribs 53 and 54. The right and left clamping jaws 51 and 52 having a plate shape are formed in front of the base 57 to be brought into contact with an insertion mechanism 200 which serves to push the clip 50 towards the inside of the main body 10, and the right ribs and left 53 and 54 are formed at the rear apex of the base 57 and extended to be slid and mounted on the flat upper surface 142 of the inclined part 140 of the main body 10, when the clip 50 is inserted in the main body 10.
The clip 50 further comprises a lower rib 55 formed at the rear of its lower part and extended to be slid and mounted on the flat lower surface 144 of the inclined part 140 of the main body 10, when the clip 50 is inserted in main body 10.
The clip 50 also includes a hole 56 formed in the base 57 of the clip 50 to fix the pin 61 to couple the upper and lower anchors 20 and 30.
Figs. 9 and 10 are diagrams illustrating a situation in which the upper and lower anchors of the cage according to a preferred embodiment of the present invention are coupled to the clip.
Referring to Figs. 9a and 9b, the lower anchor 30 is positioned inside the two arms 22 and 23 of the upper anchor 20, and the mounting holes 24 and 25 of the upper anchor 20 and the mounting holes 34 and 35 of the lower anchor 30 are aligned with each other. In such a situation, the mounting holes 24, 25, 34 and 35 of the respective anchors are aligned with the holes 56 formed in the base 57 of the clip 50, and the pin 61 is then passed through the mounting holes 24, 25 , 34 and 35 and the holes 56 of the clip 50 to couple the upper and lower anchors 20 and 30 to the clip 50.
Therefore, the upper and lower anchors 20 and 30 coupled to the clip 50 are actuated as illustrated in FIGS. 10a and 10b. More specifically, the upper blade 21 of the upper anchor 20 is turned upward around the mounting holes 24 and 25 coupled to the clip 50 and the lower blade 31 of the lower anchor 30 is turned downward around the holes of mounting 34 and 35.
Figs. 11a to 11c are detailed diagrams of the cage guiding device according to a preferred embodiment of the present invention. Fig. 11a is a perspective view, FIG. 11b is a plan view and FIG. 11c is a front view.
Referring to Figs. 11a to 11c, the guide device 40 in accordance with a preferred embodiment of the present invention is coupled to the main body 10 to guide the insertion of the clip 50 and comprises a front plate 41, left and right bars 42 and 43, holes 44, and an entry hole 46. The front plate 41 closes the front surface 103 of the main body 10. The left and right bars 42 and 43 are formed to extend from the ends of two lateral surfaces of the plate front 41 to the rear side. The holes 44 are formed in the left and right bars 42 and 43, respectively, so that the pin 60 can be inserted into the holes 44. The entry hole 46 is formed in the center of the front plate 41 to provide an opening through which the clip 50 can be inserted.
After the left and right bars 42 and 43 of the guide device 40 are inserted into the mounting grooves 151 formed in the left and right side surfaces 102 of the main body 10, the pin 60 is inserted in the hole 44 of the left bar 42 and fixed to the hole 44 of the right bar 43 by the insertion hole 120. Therefore, the main body 10 and the guide device 40 are coupled to each other.
CH 708 531 B1 In addition, the guide device 40 comprises one or more insertion holes 45 formed on its front plate 41 so that a coupling screw (not shown) fixed to a head 210 of the mechanism Insertion 200 which will be described below can be inserted into insertion hole 45.
The actuation of the cage 10 in accordance with a preferred embodiment of the present invention will be described with reference to Figs. 12a to 12d.
[0061] FIG. 12a is a perspective view illustrating a situation in which the clip has been inserted, FIG. 12b is a plan view illustrating a situation in which the clip has been inserted, FIG. 12c is a sectional view taken along the line H-H 'of FIG. 12b, illustrating a situation in which the anchors are folded, and FIG. 12d is a sectional view illustrating a situation in which the anchors are deployed.
Lacing 10 in accordance with the preferred embodiment of the present invention is actuated in such a way that the upper and lower anchors 20 and 30 are locked and fixed to the upper and lower vertebral bodies of a cervical vertebra or of a column vertebral in the area in which an intervertebral disc is removed.
First, as illustrated in Figs. 12a and 12b, the main body 10 and the guide device 40 are coupled to each other, and the right and left clamping jaws 51 and 52 of the clip 50 coupled to the upper and lower anchors 20 and 30 are pushed by the insertion mechanism 200 described below. Then, the clip 50 is inserted into the main body 10 through the entry hole 46 of the guide device 40.
In this situation, when the clip 50 is inserted, the upper and lower anchors 20 and 30 are folded so as not to project outwards from the upper and lower surfaces 101 and 104 of the main body 10, while the blades upper and lower 21 and 31 of the upper and lower anchors 20 and 30 reach the inclined upper and lower surfaces 142 and 143 of the inclined part 140 inside the main body 10, as illustrated in FIG. 12c.
Then, when the clip 50 is pushed further towards the inside of the main body 10, the upper and lower anchors 20 and 30 coupled to the clip 50 are deployed up and down as illustrated in FIG. 12d. More specifically, while they are guided along the inclined upper and lower surfaces 141 and 143 of the inclined part 140 formed in the main body 10, the upper and lower anchors 20 and 30 are moved up and down to projecting outwards from the upper and lower surfaces 101 of the main body 10, until the base 57 of the clip 50 is locked to the protuberance surface 146 formed in the center of the inclined part 140.
At this time, the right and left ribs 53 and 54 of the clip 50 are slid and installed on the flat upper surface 142 of the inclined part 140, and the lower rib 55 of the clip 50 is slid and installed on the lower surface. plane 144 of the inclined part 140.
Therefore, since the cage 1 in accordance with the preferred embodiment of the present invention comprises the upper and lower anchors for performing such an unfolding operation, it is possible to omit a complicated operation of fixing a plate by a screw in a small intervertebral space as in the prior art. Therefore, the convenience of medical treatment and the operating stability can be improved.
Figs. 13a to 13c illustrate the insertion mechanism for inserting the cage in accordance with the preferred embodiment of the present invention. Fig. 13a is a perspective view, FIG. 13b is a plan view, and FIG. 13c is a side view illustrating a situation in which the anchors are folded.
The insertion mechanism 200 is used to more stably insert the clip 50 coupled to the upper and lower anchors 20 and 30 into the main body 10 of the cage 1.
Referring to Figs. 13a to 13c, the insertion mechanism 200 for the cage 1 has a head 210 which is coupled to the guide device 40 by a coupling screw (not shown) inserted in the insertion hole 45 of the front plate 41 of the device guide 40.
The head 210 is formed with a hexahedral shape, and comprises a left part coupled to one side of a first lower support rod 220 and a right part coupled to one side of a second lower support rod 230.
In addition, a push button 240 is positioned between the first and second lower support rods 220 and 230. The push button 240 has a boss 243 formed at its end to push the clip 50 into the main body 10.
The push button 240 comprises a push plate 241, a rod body 242, and a coupling element 244. The push plate 241 is formed at the other end of the push button 240, the rod body 242 is extended from the push plate 241, and the coupling element 244 connects the rod body 242 and the hump 243. When the push plate 241 is pushed forward, the hump 243 connected to the coupling element 244 is moved forward through the rod body 242 to insert the clip 50 into the main body 10 of the cage 1 as illustrated in FIG. 13d. Then, the upper and lower anchors 20 and 30 are deployed to project outward from the upper and lower surfaces of the main body 10.
For such an operation, the head 210 includes a left head 211 coupled to the first lower support rod 220 and a right head 212 coupled to the second lower support rod 230, and the bump 243 of the push button 240 is fixed between the left and right heads 211 and 212 to move forward or backward. The other end of
CH 708 531 B1 the first lower support rod 220 and the other end of the second lower support rod 240 are inserted in a push button guide 221 in which the rod body 242 of the push button 240 is installed.
The head 210 of the insertion mechanism 200 further comprises an upper head 213 in which one end of the upper support rod 250 is inserted, and the other end of the upper support rod 250 is inserted in a guide upper support rod 251 formed at the top of the push button guide 221. In addition, a support body 252 is attached to the end of the upper support rod 250.
When the clip 50 is inserted, the upper support rod 250 is brought into contact with an upper vertebral body of a cervical vertebra or of a vertebral column, in which the cage 1 must be placed, improving in this way the stability of the insertion mechanism 200.
FIG. 14 is a diagram illustrating a situation in which the cage 10 according to the preferred embodiment of the present invention is placed. With reference to fig. 14, the cage 1 is positioned between the upper and lower vertebral bodies D1 and D2 of a cervical vertebra or a spinal column, and the clip 50 is inserted into the main body 10 by the insertion mechanism 200 in such a way that the upper and lower anchors 20 and 30 project outwards from the upper and lower surfaces 101 and 104 of the main body 10. Then, the pointed end surfaces of the upper and lower blades 21 and 31 at the ends of the anchors 20 and 30 are locked to the upper and lower vertebral bodies D1 and D2 positioned at the top and to the bottom of the cage 1 so that the cage 1 is fixed and locked between the upper and lower vertebral bodies D1 and D2.
During the actual procedure, the clip 50 is carefully and slowly inserted into the main body 10 while the push plate 241 formed at the other end of the push button 240 is struck by an operating hammer (not illustrated) .
Therefore, the upper and lower anchors 20 and 30 are positioned between the upper and lower vertebral bodies D1 and D2 to be reliably fixed to the rear internal sides of the upper and lower vertebral bodies D1 and D2. Therefore, it is possible to significantly reduce the possibility that a screw or part of a plate provided in conventional cages could interfere with the nervous tissue or blood tissue passing through the cervical vertebra or the spine in the area in which the intervertebral disc has been removed and in which the cage is installed.
While the present invention has been described in conjunction with the exemplary preferred embodiments illustrated in the drawings, they are merely indicative and the invention is not limited to these preferred embodiments. It would be appreciated by a person with average skill in the field that various equivalent modifications and variations of the embodiments can be made without departing from the spirit and scope of the present invention. Therefore, the true technical scope of the present invention should be defined by the technical spirit of the appended claims.

权利要求:
Claims (9)
[1]
1. Cage intended to be placed between two vertebral bodies, in particular cervical vertebrae, of a spinal column, comprising:
a main body (10) formed with a hexahedral shape having an upper surface (101) intended to be in contact with the first vertebral body, two lateral surfaces (102), a front surface (103), a lower surface (104) intended being in contact with the second vertebral body and a rear surface (105);
a clip (50) arranged to be inserted into the main body (10);
an upper anchor (20) coupled to the clip (50) and able to be deployed to project outward from the upper surface (101) of the main body (10) by the insertion of the clip (50);
a lower anchor (30) coupled to the clip (50) and adapted to be deployed to project outward from the lower surface (104) of the main body (10) by the insertion of the clip (50); and a guide device (40) coupled to the main body (10) for guiding the insertion of the clip (50).
[2]
2. A cage according to claim 1, in which the main body (10) comprises:
a bone fusion cavity (110) located between the upper and lower surfaces (101, 104) and the rear surface (105);
a channel (130) formed from the front surface (103) to a central portion of the main body (10) to provide a space into which the clip (50) is inserted;
an inclined portion (140) for guiding the movement of the upper and lower anchors (20 and 30); and mounting grooves (151) formed on the two lateral surfaces (102) of the main body (10) so that left and right bars (42, 43) of the guide device (40) are arranged for mounting in the respective mounting grooves (151).
[3]
3. A cage according to claim 2, in which the inclined part (140) comprises:
an inclined upper surface (141) formed to guide movement of the upper anchor (20) outward from the upper surface (101);
an inclined lower surface (143), connected to the inclined upper surface (141) and formed to guide movement of the lower anchor (30) outward from the lower surface (104);
CH 708 531 B1 a planar upper surface (142) formed at the end of the inclined upper surface (141); and a flat bottom surface (144) formed at the end of the inclined bottom surface (143).
[4]
4. A cage according to claim 2, in which the upper anchor (20) comprises:
an upper blade (21) having one end to form an upper pointed end surface;
upper anchor arms (22, 23) located on either side of the upper blade (21) and extended to be inclined towards the lower surface (104); and mounting holes (24, 25) formed at the ends of the respective upper anchor arms (22, 23) such that a pin (61) is adapted to be inserted into the mounting holes (24, 25) ; and in which the lower anchor (30) comprises:
a lower blade (31) having one end to form a lower pointed end surface;
lower anchor arms (32, 33) located on either side of the lower blade (31) and extended to be inclined towards the upper surface (101); and mounting holes (34, 35) formed at the ends of the respective lower anchor arms (32, 33) such that the pin (61) is adapted to be inserted into the mounting holes (34, 35).
[5]
5. A cage according to claim 4, in which the clip (50) comprises:
plate-shaped right and left clamping jaws (51,52), the right and left clamping jaws (51,52) each having a protrusion which extends backwards and which together form a base (57) ;
right and left ribs (53, 54) formed on the rear upper part of the base (57) to be slid and installed on the flat upper surface (142) of the inclined part (140);
a lower rib (55) formed on the rear lower part of the base (57) to be slid and installed on the flat lower surface (144) of the inclined part (140); and holes (56) located in the base (57) of the clip (50) and adapted to receive the pin (61).
[6]
6. The cage of claim 5, wherein the inclined portion (140) comprises a protrusion surface (146) formed at the connection between the upper and lower inclined surfaces (141, 142), and the protrusion surface (146) of the inclined part (140) capable of being locked inside the base (57) to stop the insertion of the clip (50) when the latter is inserted into the main body (10).
[7]
7. Cage according to claim 2, wherein the guide device (40) comprises: a front plate (41) bearing on the front surface (103) of the main body (10);
the left and right bars (42, 43) extending from both ends of the front plate (41) towards the rear surface (105);
holes (44) located respectively in the left and right bars (42, 43), said holes (44) being adapted to receive a pin (60); and an insertion hole (46) formed in the center of the front plate (41) to provide an opening through which the clip (50) is inserted.
[8]
8. The cage of claim 2, wherein sawtooth protrusions (101a, 104a) are formed on the upper and lower surfaces (101, 104) of the main body (10).
[9]
9. Insertion tool (200) for inserting a clip (50) into a main body (10) of a cage according to one of claims 1 to 8, comprising:
a head (210) able to be fixed to the guide device (40);
a first lower support rod (220) having one end coupled to the left side of the head (210); a second lower support rod (230) having one end coupled to the right side of the head (210); a push button (240) formed between the first and second lower support rods (220, 230) and having a hump (243) formed at its end and able to move forward or backward, to push the clip (50) towards the inside of the main body (10);
a push button guide (221) on which the push button (240) is installed, the push button guide (221) being adapted to receive the other end of the first lower support rod (220) and the other end the second lower support rod (230); and an upper support rod (250) capable of being coupled to an upper head (213) formed at the top of the head (210).

类似技术:

公开号 | 公开日 | 专利标题

CH708531B1|2019-05-15|Intervertebral fusion cage.

FR3016793A1|2015-07-31|ANCHORING DEVICE FOR SPINAL IMPLANT, SPINAL IMPLANT AND IMPLANTATION INSTRUMENTATION

FR2862866A1|2005-06-03|POSTERO-LATERAL INTERVERTEBRAL DISCSTRATE

FR2926453A1|2009-07-24|SPINAL OSTEOSYNTHESIS DEVICE

FR2925840A1|2009-07-03|AUTOMATED ANCILLARY INSERTION AND FIXATION BY STAPLING AN ANNULAR BODY, IN PARTICULAR A PROSTHESIS.

EP1113758A1|2001-07-11|Posterior backbone osteosynthesis device

FR2889937A1|2007-03-02|INTERVERTEBRAL IMPLANT FOR LOMBO-SACRED JOINT

FR2977140A1|2013-01-04|INTER-SPINAL IMPLANT AND IMPLANTATION INSTRUMENT

FR3020756A1|2015-11-13|VERTEBRAL IMPLANT, IMPLANT VERTEBRAL FIXATION DEVICE AND IMPLANTATION INSTRUMENTATION

FR2896404A1|2007-07-27|Surgical instrumentation kit for installing ankle prosthesis, has tibial phantom of tibial implant connected in fixed manner to phantom pad and being displaceable freely against lower end of tibia of patient

FR2752720A1|1998-03-06|SURGICAL STAPLE SUPPORT OF THE ELASTIC, SUPERELASTIC OR SHAPE MEMORY TYPE

FR3001120A3|2014-07-25|STERNUM OSTEOSYNTHESIS SYSTEM

CA2791967A1|2011-09-15|Arthrodesis implant

FR2905848A1|2008-03-21|LUMBAR INTER-SPINOUS PROSTHESIS AND ITS APPLICATIONS

FR2788958A1|2000-08-04|Tissue retractor for spinal operations with posterior access has jaws shaped to give an inner recess

CN106794067A|2017-05-31|Cup impactor

WO2009118461A1|2009-10-01|Arthrodesis system for the ankle of a human patient

EP3213704A1|2017-09-06|System of spinal arthodesis implants

FR2743490A1|1997-07-18|Staple for orthopaedic surgery

WO2006117463A1|2006-11-09|Angurlarly adjustable tibial osteotomy case

FR2927527A1|2009-08-21|Handling instrument for surgical osteosynthesis agrafe, has middle stud projected perpendicular to plane in which slideway is extended, and displacement unit i.e. mounting pad, displacing agrafe in slideway

EP3687455B1|2021-11-24|Ankle prosthesis comprising a talar implant, a tibial implant and an insert, and kit including at least one such prosthesis

EP3310282A1|2018-04-25|Implant for the fixation of bone elements

FR2797275A1|2001-02-09|METHOD FOR MEMORIZING TWO GEOMETRIC STATES OF A PRODUCT MADE IN SHAPE MEMORY ALLOY AND APPLICATIONS THEREOF TO PRODUCTS IN THE MEDICAL, DENTAL, VETERINARY OR OTHER FIELD

FR3054788A1|2018-02-09|DEPLOYABLE IMPLANT

同族专利:

公开号 | 公开日

US20200360152A1|2020-11-19|

CN104414775A|2015-03-18|

US20150127107A1|2015-05-07|

KR101555317B1|2015-10-06|

US20180104069A1|2018-04-19|

US9775722B2|2017-10-03|

CN104414775B|2016-12-07|

JP2015054235A|2015-03-23|

CN107028689A|2017-08-11|

KR20150029880A|2015-03-19|

CN107028689B|2019-03-15|

US10765531B2|2020-09-08|

BR102014018715A2|2015-09-29|

CH708531A2|2015-03-13|

引用文献:

公开号 | 申请日 | 公开日 | 申请人 | 专利标题

FR2797179B1|1999-08-03|2002-03-08|Michel Gau|INTERVERTEBRAL NUCLEAR PROSTHESIS AND SURGICAL IMPLANTATION METHOD|

FR2808995B1|2000-05-18|2003-02-21|Aesculap Sa|INTERSOMATIC CAGE WITH UNIFIED GRAFT|

US6447546B1|2000-08-11|2002-09-10|Dale G. Bramlet|Apparatus and method for fusing opposing spinal vertebrae|

FR2823095B1|2001-04-06|2004-02-06|Ldr Medical|RACHIS OSTEOSYNTHESIS DEVICE AND PLACEMENT METHOD|

FR2824261B1|2001-05-04|2004-05-28|Ldr Medical|INTERVERTEBRAL DISC PROSTHESIS AND IMPLEMENTATION METHOD AND TOOLS|

FR2827156B1|2001-07-13|2003-11-14|Ldr Medical|VERTEBRAL CAGE DEVICE WITH MODULAR FASTENING|

FR2831048B1|2001-10-18|2004-09-17|Ldr Medical|PROGRESSIVE APPROACH OSTEOSYNTHESIS DEVICE AND PRE-ASSEMBLY PROCESS|

FR2831049B1|2001-10-18|2004-08-13|Ldr Medical|PLATE FOR OSTEOSYNTHESIS DEVICE AND PRE-ASSEMBLY METHOD|

FR2831796B1|2001-11-06|2003-12-26|Ldr Medical|BONE ANCHORING DEVICE FOR PROSTHESIS|

FR2833151B1|2001-12-12|2004-09-17|Ldr Medical|BONE ANCHORING IMPLANT WITH POLYAXIAL HEAD|

FR2846550B1|2002-11-05|2006-01-13|Ldr Medical|INTERVERTEBRAL DISC PROSTHESIS|

FR2859095B1|2003-09-01|2006-05-12|Ldr Medical|BONE ANCHORING IMPLANT WITH A POLYAXIAL HEAD AND METHOD OF PLACING THE IMPLANT|

FR2860701B1|2003-10-09|2006-01-06|Ldr Medical|DEVICE AND METHOD FOR SECTIONING THE BLADE OF A VERTEBRA|

FR2865629B1|2004-02-04|2007-01-26|Ldr Medical|INTERVERTEBRAL DISC PROSTHESIS|

JP4996927B2|2004-02-04|2012-08-08|エル・デ・エール・メデイカル|Intervertebral disc prosthesis|

FR2869528B1|2004-04-28|2007-02-02|Ldr Medical|INTERVERTEBRAL DISC PROSTHESIS|

FR2879436B1|2004-12-22|2007-03-09|Ldr Medical|INTERVERTEBRAL DISC PROSTHESIS|

FR2887762B1|2005-06-29|2007-10-12|Ldr Medical Soc Par Actions Si|INTERVERTEBRAL DISC PROSTHESIS INSERTION INSTRUMENTATION BETWEEN VERTEBRATES|

FR2891135B1|2005-09-23|2008-09-12|Ldr Medical Sarl|INTERVERTEBRAL DISC PROSTHESIS|

FR2893838B1|2005-11-30|2008-08-08|Ldr Medical Soc Par Actions Si|PROSTHESIS OF INTERVERTEBRAL DISC AND INSTRUMENTATION OF INSERTION OF THE PROSTHESIS BETWEEN VERTEBRATES|

FR2897259B1|2006-02-15|2008-05-09|Ldr Medical Soc Par Actions Si|INTERSOMATIC TRANSFORAMINAL CAGE WITH INTERBREBAL FUSION GRAFT AND CAGE IMPLANTATION INSTRUMENT|

FR2910267B1|2006-12-21|2009-01-23|Ldr Medical Soc Par Actions Si|VERTEBRAL SUPPORT DEVICE|

US8465546B2|2007-02-16|2013-06-18|Ldr Medical|Intervertebral disc prosthesis insertion assemblies|

FR2916956B1|2007-06-08|2012-12-14|Ldr Medical|INTERSOMATIC CAGE, INTERVERTEBRAL PROSTHESIS, ANCHORING DEVICE AND IMPLANTATION INSTRUMENTATION|

FR2917287B1|2007-06-15|2010-09-03|Ldr Medical|INTERVERTEBRAL PROSTHESIS|

FR2918555B1|2007-07-12|2010-04-02|Ldr Medical|DEVICE AND SYSTEM FOR TRANSVERSE SPINACH CONNECTION|

FR2926457A1|2008-01-17|2009-07-24|Warsaw Orthopedic Inc|INTERVERTEBRAL CAGE AND VERTEBRAL FUSION DEVICE HAVING THE SAME|

CN201244104Y|2008-06-27|2009-05-27|常州奥斯迈医疗器械有限公司|Intervertebral fusion device for locking anterior lumbar interbody|

WO2010028045A1|2008-09-02|2010-03-11|Synthes Usa, Llc|Intervertebral implant with blades for connecting to adjacent vertebral bodies|

US8137405B2|2008-10-08|2012-03-20|K2M, Inc.|Spinal interbody spacer|

JP5553268B2|2009-02-10|2014-07-16|学校法人自治医科大学|Interbody fusion surgery system and interbody fusion space holding device for interbody fusion surgery|

US8349015B2|2009-02-11|2013-01-08|Howmedica Osteonics Corp.|Intervertebral implant with integrated fixation|

CN102458278B|2009-04-15|2016-03-16|斯恩蒂斯有限公司|Arcuate fixation member|

US8641766B2|2009-04-15|2014-02-04|DePuy Synthes Products, LLC|Arcuate fixation member|

US8343223B2|2009-07-14|2013-01-01|Life Spine, Inc.|Combined spinal interbody and plate assemblies|

CA2773723C|2009-09-17|2017-10-31|Synthes Usa, Llc|Intervertebral implant having extendable bone fixation members|

KR101636010B1|2009-12-31|2016-07-04|엘디알 메디칼, 에스.에이.에스.|Anchoring device, interbertebral implant and implantation instrument|

US20120078373A1|2010-09-23|2012-03-29|Thomas Gamache|Stand alone intervertebral fusion device|

US20120078372A1|2010-09-23|2012-03-29|Thomas Gamache|Novel implant inserter having a laterally-extending dovetail engagement feature|

US20120078371A1|2010-09-23|2012-03-29|Thomas Gamache|Fusion cage with in-line single piece fixation|

US20120150300A1|2010-12-08|2012-06-14|Raj Nihalani|Inter-vertebral-body spacer|

FR2977139B1|2011-06-30|2014-08-22|Ldr Medical|INTER-SPINAL IMPLANT AND IMPLANTATION INSTRUMENT|

US8460388B2|2011-10-28|2013-06-11|Incite Innovation Llc|Spinal interbody device|

EP2628466B1|2012-02-17|2017-04-05|Medacta International S.A.|Intervertebral implant with improved fastening system for the fixing plate|

FR2987256B1|2012-02-24|2014-08-08|Ldr Medical|ANCHORING DEVICE FOR INTERVERTEBRAL IMPLANT, INTERVERTEBRAL IMPLANT AND IMPLANTATION INSTRUMENTATION|

FR3005569B1|2013-05-16|2021-09-03|Ldr Medical|VERTEBRAL IMPLANT, VERTEBRAL IMPLANT FIXATION DEVICE AND IMPLANTATION INSTRUMENTATION|

KR101555317B1|2013-09-11|2015-10-06|주식회사 솔고 바이오메디칼|Cage having the spike|

FR3016793B1|2014-01-30|2021-05-07|Ldr Medical|ANCHORING DEVICE FOR SPINAL IMPLANT, SPINAL IMPLANT AND IMPLANTATION INSTRUMENTATION|

FR3020756A1|2014-05-06|2015-11-13|Ldr Medical|VERTEBRAL IMPLANT, IMPLANT VERTEBRAL FIXATION DEVICE AND IMPLANTATION INSTRUMENTATION|

FR3024351B1|2014-08-01|2021-11-19|Ldr Medical|BONE IMPLANTS|

US10258479B2|2015-08-15|2019-04-16|Ldr Medical|Devices, methods, and systems to implant and secure a fusion cage or intervertebral prosthesis for spinal treatment|

FR3048176A1|2016-02-26|2017-09-01|Ldr Medical|SPINAL ARTHRODESIS IMPLANT SYSTEM|

US10060862B2|2016-04-18|2018-08-28|Board of Trustees of the Leland Stanford Junior Univers|Microwave impedance microscopy using a tuning fork|

FR3050634A1|2016-04-28|2017-11-03|Ldr Medical|BONE ANCHORING SYSTEM, IMPLANT AND INSTRUMENTATION THEREFOR|FR2897259B1|2006-02-15|2008-05-09|Ldr Medical Soc Par Actions Si|INTERSOMATIC TRANSFORAMINAL CAGE WITH INTERBREBAL FUSION GRAFT AND CAGE IMPLANTATION INSTRUMENT|

KR101636010B1|2009-12-31|2016-07-04|엘디알 메디칼, 에스.에이.에스.|Anchoring device, interbertebral implant and implantation instrument|

US9987142B2|2012-08-31|2018-06-05|Institute for Musculoskeletal Science and Education, Ltd.|Fixation devices for anterior lumbar or cervical interbody fusion|

FR3005569B1|2013-05-16|2021-09-03|Ldr Medical|VERTEBRAL IMPLANT, VERTEBRAL IMPLANT FIXATION DEVICE AND IMPLANTATION INSTRUMENTATION|

KR101555317B1|2013-09-11|2015-10-06|주식회사 솔고 바이오메디칼|Cage having the spike|

US9968464B2|2014-01-17|2018-05-15|Spine Wave, Inc.|Spinal fusion system|

FR3016793B1|2014-01-30|2021-05-07|Ldr Medical|ANCHORING DEVICE FOR SPINAL IMPLANT, SPINAL IMPLANT AND IMPLANTATION INSTRUMENTATION|

FR3020756A1|2014-05-06|2015-11-13|Ldr Medical|VERTEBRAL IMPLANT, IMPLANT VERTEBRAL FIXATION DEVICE AND IMPLANTATION INSTRUMENTATION|

US10433975B2|2015-05-21|2019-10-08|Globus Medical, Inc.|Device and method for deployment of an anchoring device for intervertebral spinal fusion|

EP3354234A1|2017-01-27|2018-08-01|Globus Medical, Inc.|Device for deployment of an anchoring device for intervertebral spinal fusion|

US10376378B2|2015-05-21|2019-08-13|Globus Medical, Inc.|Device and method for deployment of an anchoring device for intervertebral spinal fusion|

US10765532B2|2015-05-21|2020-09-08|Globus Medical, Inc.|Device and method for deployment of an anchoring device for intervertebral spinal fusion|

US10433980B2|2015-05-21|2019-10-08|Globus Medical, Inc.|Device and method for deployment of an anchoring device for intervertebral spinal fusion|

US10137005B2|2015-05-21|2018-11-27|Globus Medical, Inc.|Device and method for deployment of an anchoring device for intervertebral spinal fusion|

JP6643364B2|2015-06-25|2020-02-12|インスティテュートフォーマスキュロスケレタルサイエンスアンドエジュケイション，リミテッド|Interbody fusion device and system for implantation|

US10258479B2|2015-08-15|2019-04-16|Ldr Medical|Devices, methods, and systems to implant and secure a fusion cage or intervertebral prosthesis for spinal treatment|

FR3048176A1|2016-02-26|2017-09-01|Ldr Medical|SPINAL ARTHRODESIS IMPLANT SYSTEM|

CA3024894A1|2016-05-25|2017-11-30|Genesys Spine|Stand alone interbody spinal system|

US10307265B2|2016-10-18|2019-06-04|Institute for Musculoskeletal Science and Education, Ltd.|Implant with deployable blades|

US10449060B2|2016-10-25|2019-10-22|Institute for Musculoskeletal Science and Education, Ltd.|Spinal fusion implant|

US10405992B2|2016-10-25|2019-09-10|Institute for Musculoskeletal Science and Education, Ltd.|Spinal fusion implant|

FR3058042B1|2016-10-27|2021-12-10|Ldr Medical|EXPANDABLE INTERVERTEBRAL IMPLANT|

US9937055B1|2016-11-28|2018-04-10|Spine Wave, Inc.|Scoring implant trial and implant inserter for spinal fusion system|

WO2018195260A1|2017-04-19|2018-10-25|Life Spine Inc. |Stand-alone alif spine implants|

US10932919B2|2017-07-18|2021-03-02|Blue Sky Technologies, LLC|Spinal implant system|

US10888435B2|2017-10-05|2021-01-12|Spine Wave, Inc.|Modular inserter for anterior cervical cage|

US10925748B2|2018-01-25|2021-02-23|Alliance Partners, Llc|Medical implant having an anchoring system and method of use thereof|

KR20190102897A|2018-02-27|2019-09-04|엘앤케이바이오메드|Integrated Lumbar Interbody Fusion Cage|

US10849758B2|2018-08-22|2020-12-01|Institute for Musculoskeletal Science and Education, Ltd.|Spinal fusion implant|

US11160589B1|2020-09-21|2021-11-02|Randall F. Lee|System and method for joining boney structures|

法律状态:
2016-05-13| PUE| Assignment|Owner name: LDR MEDICAL S.A.S., FR Free format text: FORMER OWNER: SOLCO BIOMEDICAL CO., LTD., KR |

2020-05-29| PL| Patent ceased|

优先权:

申请号 | 申请日 | 专利标题

KR1020130108840A|KR101555317B1|2013-09-11|2013-09-11|Cage having the spike|

[返回顶部]