implant with structural members arranged around a ring

专利摘要:
an implant for use in a spine includes a body and a plurality of structural members. the upper and lower surfaces include a ring and structural members arranged in a weft-like pattern around the ring. the bone contact members are arranged radially away from the ring and the support members are arranged in a circumferential direction around the ring.
公开号:BR112019018977A2
申请号:R112019018977
申请日:2018-03-12
公开日:2020-04-28
发明作者:S. Bishop Sean；J. Ryan Christopher；J. McShane Edward III；A. Stauffer Megan；M. Naahay Joseph
申请人:Institute for Musculoskeletal Science and Education, Ltd.；
IPC主号:

专利说明:

IMPLANT WITH STRUCTURAL MEMBERS PLACED AROUND A RING
BACKGROUND [001] The modalities are generally aimed at implants to support bone growth in a patient.
[002] A variety of different implants are used in the body. The implants used in the body to stabilize an area and promote bone growth provide stability (that is, minimal deformation under pressure over time) and space for bone growth.
[003] Spinal fusion, also known as spondylolysis or spondylosyndesis, is a surgical treatment method used to treat various morbidities, such as: degenerative disc disease, spondylolisthesis (slipping of a vertebra), spinal stenosis, scoliosis, fracture , infection or tumor. The purpose of the spinal fusion procedure is to reduce instability and therefore pain.
[004] In preparation for spinal fusion, most of the intervertebral disc is removed. An implant, the spinal fusion box, can be placed between the vertebra to maintain spine alignment and disc height. The fusion, that is, bone bridge, occurs between the end plates of the vertebrae.
SUMMARY [005] In one aspect, an implant includes a body including a ring with an opening. The body defines a transverse plane that divides the implant into an upper half and a lower half. The ring defines a radial and a circumferential direction. The implant includes a limb from
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2/43 bone contact attached to the ring, where the bone contact member extends radially from the ring. The implant also includes a support member attached to the bone contact member in a fixation region, where the support member extends in the circumferential direction.
[006] In another aspect, an implant includes a body. The body defines a transverse plane that divides the implant into an upper half and a lower half. The implant includes a first bone contact member attached to the body and disposed in the upper half of the implant. The implant also includes a first support member attached to the first bone contact member, the first support member being disposed within the upper half of the implant. The implant also includes a second bone contact member attached to the body and disposed in the lower half of the implant. The implant also includes a second support member attached to the second bone contact member, the second support member being disposed within the lower half of the implant. An end of the first support member is attached to the end of the second support member.
[007] In another aspect, an implant includes a body and a plurality of members of bone contact that extend from a central region of the body to a periphery of the body. Each of the bone contact members in the plurality of bone contact members extends radially away from the central region of the body.
[008] Other systems, methods, characteristics and advantages of the modalities will be or will become evident to a person with common knowledge in the technique after examining the following figures and detailed description. Intends
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3/43 it is understood that all such systems, methods, characteristics and additional advantages are included in this description and in this summary, are within the scope of the modalities, and are protected by the following claims.
BRIEF DESCRIPTION OF THE DRAWINGS [009] The modalities can be better understood with reference to the following drawings and description. The components in the figures are not necessarily to scale, but emphasis is placed instead on illustrating the principles of the modalities. In addition, in the figures, the reference numbers designate corresponding parts throughout the different views.
[0010] Figure 1 is a schematic top isometric view of an embodiment of an implant;
[0011] Figure 2 is a schematic isometric bottom view of the implant of Figure 1;
[0012] Figure 3 is a schematic isometric view of an implant body of Figure 1 shown in isolation;
[0013] Figure 4 is a schematic side view of the implant of Figure 1;
[0014] Figure 5 is a schematic isometric view of the implant of Figure 1, including an enlarged sectional view of a structural member;
[0015] Figure 6 is a schematic isometric view of a plurality of support members disposed within the implant body of Figure 1;
[0016] Figure 7 is a schematic side view of the implant of Figure 1;
[0017] Figure 8 is a schematic side view of the Figure 1 implant, in which the body was removed for purposes
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4/43 clarity;
[0018] Figure 9 is a schematic isometric view of the implant of Figure 1, in which the limb curves of several structural members are illustrated;
[0019] Figure 10 is a schematic top view of an embodiment of an implant;
[0020] Figure 11 is a diagram representing an implant connected to an implant tool, and where the implant is covered with bone growth promoting material, according to one modality;
[0021] Figure 12 is a schematic isometric view of an implant being positioned for insertion between two vertebrae, according to one modality;
[0022] Figure 13 is a schematic isometric view of the Figure 12 implant inserted between the two vertebrae;
[0023] Figure 14 is a schematic side view of the Figure 13 implant including a partial section view of a central cavity;
[0024] Figure 15 is a schematic side view of the Figure 13 implant indicating areas of new bone growth;
[0025] Figure 16 is a schematic side view of the Figure 13 implant indicating areas of new bone growth;
[0026] Figure 17 is a schematic isometric view of the implant of Figure 13 including an enlarged view of the upper side of the implant;
[0027] Figure 18 is a schematic isometric view of the Figure 13 implant indicating areas of new bone growth on the upper side of the implant;
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5/43 [0028] Figure 19 is a schematic isometric view of the Figure 13 implant indicating areas of new bone growth on the upper side of the implant; and [0029] Figure 20 is a schematic isometric view of the new bone growth that covers the implant in Figure 13.
DETAILED DESCRIPTION [0030] The modalities described here are aimed at an implant for use in a spine. The modalities include implants with a body and one or more structural members. In addition to the various provisions discussed below, any modalities may make use of any of the body / support structures, frames, plates, coils or other structures disclosed in Morris et al., US Publication Number ________, published on ______, currently in the Order US Patent No. 15/141, 655, filed on April 28, 2016 and entitled Coiled Implants and Systems and Methods of Use thereof, which is hereby incorporated by reference in its entirety. For convenience, the Morris order will be referred to throughout the order as The Rolled Implant Order. In addition, any modalities may make use of any of the body / support structures, elements, frames, plates or other structures disclosed in McShane III et al., US Publication Number ________, published on ______, currently US Patent Application N °. 15/334053, deposited on October 25, 2016 and entitled Implant with Arched Bone Contact Elements (Attorney Document No. 138-1009), which is incorporated by reference in its entirety. In addition, any modalities can make use of any of the structures, elements, frames, plates or other
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6/43 structures disclosed in McShane III et al., US Publication Number ________, published in ______, currently US Patent Application No. 15/334022, filed on October 25, 2016 and entitled Implant with Protected Fusion Zones (Attorney Document No. 138-1007), which is incorporated by reference in its entirety and referred to as The Protective Fusion Zones application.
[0031] Figures 1 and 2 illustrate isometric views of an embodiment of an implant 100, which can alternatively be referred to as a device. Specifically, Figure 1 is an isometric view of the top or top side of the implant 100, while Figure 2 is an isometric view of the bottom or bottom side of the implant 100. The implant 100 can also be referred to as a cash or merger. In some embodiments, implant 100 is configured to be implanted within a part of the human body. In some embodiments, implant 100 can be configured for implantation in the spine. In some embodiments, implant 100 may be a spinal fusion implant, or spinal fusion device, which is inserted between adjacent vertebrae to provide support and / or facilitate fusion between the vertebrae.
[0032] In some embodiments, implant 100 can include a body 102. Body 102 can generally provide a structure or skeleton for implant 100. In some embodiments, implant 100 can also include a plurality of structural members 104. The plurality of structural members 104 can be fixedly fixed to the body and / or continuously formed (or integrally formed) with the body 102.
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7/43 [0033] As used herein, the term fixedly fixed refers to two components joined in such a way that the components may not be easily separated (for example, without destroying one or both components). As used herein, each structural member comprises a distinct member or element that measures a portion of an implant. Structural members can overlap or intersect, similar to elements in a lattice or other 3D mesh structure. Some modalities may use structural members in which the length of the member is greater than its width and thickness. In the modalities in which a structural member has an approximately circular cross-sectional shape, the structural member has a length greater than its diameter. In the modalities seen in Figures 1-2, each structural member is seen to have a shape of approximately rounded or circular cross-section (that is, the member has the geometry of a solid tube). However, in other embodiments, a structural member may have any other form of cross-section, including, but not limited to, various forms of polygonal cross-section, as well as any other forms of regular and / or irregular cross-section. In some cases, for example, the size of the cross section and / or the shape of a structural member may vary along its length (for example, the diameter may change along its length).
[0034] For the sake of clarity, reference is made to several directional adjectives throughout the detailed description and in the claims. As used herein, the previous term refers to a side or part of an implant that is intended to be oriented towards the front of the human body when the implant
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8/43 was placed on the body. Likewise, the term later refers to a side or portion of an implant that is intended to be oriented towards the back of the human body after implantation. In addition, the upper term refers to a side or portion of an implant that must be oriented towards a top (for example, the head) of the body while the lower one refers to a side or portion of an implant that is intended to be oriented to a bottom of the body. Reference is also made here to sides or sides of an implant, which are sides, or parts, facing along a lateral direction of the body (which corresponds to the left or right sides of a patient).
[0035] In Figures 1-2, the implant 100 must be configured with an anterior side 110 and a posterior side 112. The implant 100 can also include a first lateral side 114 and a second lateral side 116 that extend between the posterior side 112 and the front side 110 on opposite sides of the implant 100. In addition, the implant 100 can also include an upper side 130 and a lower side 140.
[0036] Reference is also made to the directions or axes related to the implant itself, and not to the intended orientation in relation to the body. For example, the term distal refers to a part that is located farthest from the center of an implant, while the term proximal refers to a part that is located closest to the center of the implant. As used herein, the center of the implant can be the center of mass and / or a central plane and / or another centrally located reference surface.
[0037] An implant can also be associated with several axes. With reference to Figure 1, implant 100 may be
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9/43 associated with a longitudinal geometric axis 120 that extends along the largest dimension of the implant 100 between the first lateral side 114 and the second lateral side 116. In addition, the implant 100 can be associated with a posterior-anterior geometric axis 122 (also referred to as a transverse geometric axis) that extends along the transverse dimension of the implant 100, between the posterior side 112 and the anterior side 110. In addition, the implant 100 can be associated with a vertical geometric axis 124 that extends along the thickness dimension of the implant 100 and which is generally perpendicular to both the longitudinal axis 120 and the posterior-anterior axis 122.
[0038] An implant can also be associated with several reference planes or surfaces. As used here, the term median plane refers to a vertical plane that passes from the anterior side to the posterior side of the implant, dividing the implant into right and left halves, or lateral halves. As used here, the term transverse plane refers to a horizontal plane located in the center of the implant that divides the implant into upper and lower halves. As used here, the term coronal plane refers to a vertical plane located in the center of the implant that divides the implant into anterior and posterior halves. In some modalities, the implant is symmetrical around two planes, such as the median and transversal planes.
[0039] Figure 3 illustrates a schematic isometric view of body 102 in isolation, with the plurality of structural members 104 removed for clarity purposes. In some embodiments, a body may include portions of
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10/43 distinct structures that are oriented in different directions. In the embodiment shown in Figure 3, the body 102 includes a portion of peripheral structure 200, also referred to as simply peripheral portion 200. In some embodiments, peripheral portion 200 has a longer dimension aligned with longitudinal axis 120 and a dimension in width (for example, the second longest dimension) aligned with the posterior-anterior axis 122 of the implant 100 (see Figures 1 and 2). The peripheral frame portion 200 comprises a first side frame portion 202, a second side frame portion 204 and a rear frame portion 206, which are mainly in the transverse plane.
[0040] In some embodiments, one or more sides of an implant (including lateral sides and / or anterior / posterior sides) may include a vertically oriented portion of peripheral structure. In the embodiment of Figure 3, the body 102 is seen to include a vertically oriented peripheral structure portion 208 arranged on the anterior side 110, which can also be referred to as an anterior wall of the implant 100. In contrast, the posterior side 112 lacks any structure or wall portion extending vertically beyond the thickness of the peripheral portion 200 in the modalities of Figures 3-4. The presence of the vertically oriented peripheral structure portion 208 can improve support and resistance against vertical loads applied along the anterior side of the spine.
[0041] Although the present modality uses a structure or wall oriented vertically on the anterior side of the implant 100, in other modalities, a structure or wall oriented
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11/43 vertically it can be located on the posterior side of the implant 100 and / or on the lateral side of the implant 100. In other modalities, the implant may not have vertical walls along its perimeter (that is, along the posterior sides, anterior or lateral).
[0042] Modalities can include one or more rings. In some embodiments, an implant may include two or more rings that are connected in a set of rings. As seen in Figure 3, the body 102 includes a ring assembly 220. The ring assembly 220 further comprises an upper ring 222 and a lower ring 224. In addition, the ring assembly 220 includes a first support 226 and a second support 228 extending through an interior region (and crossing the transverse plane) of the implant 100 and joining the upper ring 222 and the lower ring 224.
[0043] As seen in Figure 3, ring assembly 220 can be arranged to form a hollow cylinder, which includes openings 230. This geometry can provide a tubular space (central cavity 231) through which bone growth from vertebrae opposites can extend and merge in the center of the implant, thus forming a strong cylindrical column of bone growth. In addition, the presence of openings 230 may allow new bone growth to extend from the spine and merge with bone growth occurring in adjacent regions within the implant 100. Optionally, in other embodiments, a ring assembly may comprise continuous cylindrical walls without openings.
[0044] In different modalities, the location of a ring set may vary. For the purpose of characterizing
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12/43 possible locations of a ring set, an implant can be divided into a first lateral region, a second lateral region and a central region disposed between the first lateral region and the second lateral region. In the exemplary embodiment of Figure 3, the implant 100 includes a first lateral region 240, a central region 242 and a second lateral region 244. In the exemplary embodiment, therefore, the set of rings 220 is arranged in the central region 242 and approximately equally spaced at from opposite side ends. Obviously, in other embodiments, the ring assembly 220 can be arranged in the first side region 240 or in the second side region 244.
[0045] It can be appreciated that in other modalities a ring set can be arranged centrally in relation to a posterior / anterior direction. Although, in the present embodiment, the set of rings 220 extends the entire distance between the posterior and anterior edges of the implant 100.
[0046] In different modalities, the shape of a ring can vary. In the exemplary embodiment, the upper ring 222 and the lower ring 224 each have an oval shape. However, in other embodiments, a ring can have any other shape, including, but not limited to, a round shape, a circular shape, a triangular shape, a square shape, a polygonal shape, a regular shape, an irregular shape, etc. .
[0047] A ring set, including an upper ring and a lower ring, can be attached to other portions of the implant in several ways. In some embodiments, a ring assembly may be attached directly to a peripheral body portion of a body. In other modalities, a
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13/43 ring assembly can be attached to the body by means of one or more structural members. In the exemplary embodiment, the ring assembly 220 is attached directly to the peripheral structure portion 206 and the vertically oriented peripheral structure portion 208, while also being attached to a plurality of structural members (see Figures 1-2).
[0048] Figure 4 is a side view of an embodiment of the implant 100. In some embodiments, the vertically oriented peripheral structure portion 208 may include openings. In other embodiments, the vertically oriented peripheral structure portion 208 may not include openings. In some embodiments, openings in a portion of the structure can provide an access point for inserting bone graft material or BGPM into an implant. The number, size and / or shape of the openings in the vertically oriented peripheral structure portion 208 may vary. In some cases, three or more openings can be used. In other cases, two openings can be used. In still other cases, a single opening can be used. Exemplary forms of openings that can be used include, but are not limited to, rounded openings, rectangular openings, polygonal openings, regular openings and / or irregular openings. In the embodiment of Figures 3-4, the vertically oriented peripheral structure portion 208 includes two large oval shaped windows that can facilitate the insertion of bone graft material (or BGMP) into the implant. Specifically, the vertically oriented peripheral frame portion 208 includes the first window 210 and the second window 212.
[0049] Some modalities may include provisions that
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14/43 facilitate implantation, including insertion and / or fixation of the implant. Some modalities may include a fastener receiving portion. For example, as best seen in Figures 1-2, the implant 100 includes a fastener receiving portion 160. The fastening receiving portion 160 includes a threaded opening 162 and a reinforced collar 164 to support the threaded opening 162. In In some embodiments, the threaded opening 162 can be configured to receive a tool with a corresponding threaded tip to facilitate implantation of the implant 100. In some instances, the threaded opening 162 can be used with a screw to help connect the implant 100 to a bone or other fixation device. In other embodiments, any other features for receiving fasteners and / or implantation tools can be incorporated into the implant 100.
[0050] In some modalities, an implant can be configured with one or more symmetries. In some cases, an implant may have mirrored symmetry with respect to one or more reference planes.
[0051] With reference to Figures 1 and 2, the implant 100 can include at least one mirror symmetry. For reference purposes, implant 100 can be divided into an upper half and a lower half. Here, the upper half of the implant 100 includes the body portions 102 and the plurality of structural members 104 arranged above the transverse plane. Likewise, the lower half of the implant 100 includes the body portions 102 and the plurality of structural members 104 arranged below the transverse.
[0052] In relation to the transversal plane (which coincides
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15/43 generally with the plane defined by the first portion of lateral structure 202, second portion of lateral structure 204 and portion of posterior structure 206), it can be seen that the upper half of implant 100 mirrors the lower half of implant 100, at least least approximately. This includes not only the geometry of the body, but also the shape, size and orientations of each structural member.
[0053] Furthermore, in relation to the median plane (which approximately divides the implant 100 into two lateral halves), it can be seen that two lateral halves mirror each other approximately. This includes not only the geometry of the body but also the shape, size and orientations of each structural member.
[0054] An implant can include two or more types of structural members (or structural elements). In some embodiments, an implant may include one or more structural members in contact with the bone, or simply members of bone contact. Bone contact members can generally be fully exposed on the external surfaces of an implant, including along the upper and lower sides of the implant. Thus, bone contact members can alternatively be referred to as external members.
[0055] In some embodiments, an implant may include one or more structural members that support one or more members of bone contact. These structural support members can be referred to as support members. In some embodiments, at least some portions of each support member can be hidden or covered by a bone contact member or another element of the implant. Like this,
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16/43 the support members can also be characterized as internal members, as they are usually arranged into the bone contact members.
[0056] Figure 5 illustrates a schematic isometric view of implant 100, according to one embodiment. As seen in Figure 5, implant 100 may include a plurality of bone contact members 180 as well as a plurality of support members 182. As best shown in Figures 1-2, the plurality of structural members 104 are arranged in four distinct quadrants in implant 100: a first quadrant associated with the upper side 130 and the first lateral region 240; a second quadrant associated with the upper side 130 and a second lateral region 244; a third quadrant associated with the lower side 140 and the first lateral region 240; and a fourth quadrant associated with the lower side 140 and the second lateral region 244.
[0057] The following discussion discusses exemplary structural members in some, but not all, of the implant 100 quadrants. However, it can be appreciated that similar properties and principles of the specific structural members discussed here can apply to structural members in any one of the remaining quadrants.
[0058] In some embodiments, one or more structural members can be closed loops without ends. In other embodiments, at least some structural member comprises two ends. In some cases, structural members with two ends may include one or more ends connected to another structural member. In other cases, structural members with two ends can be arranged so that both ends are
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17/43 attached to a part of the body of an implant. In the exemplary embodiment shown in Figure 5, each structural member includes two ends, each end being connected to a portion of the body 102, or connected to another structural member of the implant 100.
[0059] In some embodiments, an implant may include at least one bone contact member with one end attached to a portion of the structure and the other end attached to a central ring. For example, as seen in Figure 5, a bone contact member 300 includes a first end 302 attached to the upper ring 222 and a second end 304 attached to the first side structure 202.
[0060] In different modalities, the support members can be attached to different parts of an implant. In some embodiments, one or more ends of a support member can be attached to a peripheral structure portion of a body. In other embodiments, one or more ends can be attached to another support member. In still other embodiments, one or more portions of a support member can be attached to a bone contact member. In one embodiment, each support member can be attached to a portion of the body's peripheral structure, at least one bone contact member, and at least one other support member.
[0061] In the exemplary embodiment of Figure 5, each support member includes an end that is connected to a portion of peripheral structure. For example, support member 340 includes a first end 342 that is attached to the rear frame portion 206. Likewise, the remaining support members of the plurality of support members
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18/43 support 182 each has an end attached to the peripheral structure portion 206 or the vertically oriented peripheral structure portion 208.
[0062] Modalities may include provisions to minimize the number of bars or other necessary supports. Some embodiments may include arrangements that eliminate the need for any internal supports that extend between the peripheral structure portion 200 (shown in Figure 5) and the set of rings 220, thereby increasing the interior volume available to receive new bone growth. In some embodiments, support members from opposite upper and lower sides of an implant can connect directly to each other, thus eliminating the need for additional longitudinal running structures to receive the support members.
[0063] Figure 6 is a schematic isometric view of the plurality of support members 182 with the body 102 shown in phantom for purposes of clarity. Figure 7 illustrates a schematic side end view of implant 100, while Figure 8 illustrates a similar view with body 102 removed for purposes of illustration. As seen in Figures 6-8, each support member includes an end that is joined to three other support members in an area adjacent to the transverse plane. As an example, the first upper support member 402, the second upper support member 404, the first lower support member 406 and the second lower support member 408 are all joined in a fixing region 410 which is located approximately on the plane view of implant 100. Specifically, as best seen in Figure 8, a 403 end of the first
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19/43 upper support member 402, an end 405 of the second upper support member 404, an end 407 of the first lower support member 406 and an end 409 of the second lower support member 408 are all together. Using this arrangement, the support members provide reinforcement and support in the posterior-anterior and vertical directions of the implant 100 without the need for additional support elements (for example, longitudinally functioning beams, bars or plates) that would serve as attachment points for support members in the center of the implant.
[0064] In some embodiments, the bone contact members can be arranged distally to support the limbs, with the bone contact members generally arranged further out along the upper and lower sides of an implant. Thus, bone contact members can generally be arranged closer to the vertebral end plates after implantation in the spine. In addition, in regions where a bone contact member is attached to a support member, the fixed portion of the bone contact member can be arranged distally to the fixed portion of the inner member. As an example, Figure 5 illustrates a schematic isometric view of implant 100, including an enlarged cross section view of a fixation region 189 between bone contact member 370 and support member 390. Here, the bone contact member 370 is seen extending upward and over the support member 390. In addition, the bone contact member 370 is seen as located distally to support the member 390. Here, distally, it is meant to be disposed further away from the plane view of implant 100.
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20/43 [0065] Modalities may include provisions to protect bone growth along and adjacent to bone contact members of an implant. In some embodiments, a bone contact member can be configured with a geometry that helps to protect new bone growth in selected regions or protected fusion zones. In some embodiments, a bone contact member may have a spiral, helical, or twisted geometry that provides a series of these protected fusion zones for improved bone growth.
[0066] Some members in contact with the bones may have a generalized helical geometry. As used here, a generalized helical geometry or spiral geometry refers to a geometry where a part (portion, member, etc.) curls, rotates, twists, rotates or is curved around a fixed path. In some cases, the fixed path can be straight. In other cases, the fixed path can be curved. In the present embodiments, for example, the fixed path is generally a combination of straight and curved segments.
[0067] Curves with a generalized helical geometry (also called generalized helical curves) can be characterized by coils, turns or windings over a fixed path. Exemplary parameters that can characterize the specific geometry of a generalized helical curve can include the diameter of the coil (including the largest and smallest diameter) and the pitch (that is, spacing between adjacent coils). In some cases, the width of a coil or loop can also be used to describe the diameter or
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21/43 the width of the coil or loop. Each of these parameters can be constant or vary over the length of a generalized helical curve.
[0068] Generalized helical curves need not be circular or even round. In some embodiments, for example, a generalized helical curve could have a linearly segmented shape (or a local polygonal shape) such that each coil or loop is composed of straight line segments instead of arcs or other curved segments. Generalized helical curves can also include combinations of curved and straight segments. Examples of generalized helical curves are shown and described in The Application of Protected Fusion Zones.
[0069] For the purpose of characterizing the geometry of one or more structural members, each structural member can be understood as having a central member curve. The central member curve of each structural member can be defined as a curve that extends along the length of the structural member so that each point along the curve is positioned centrally within the structural member.
[0070] In the modalities in which a structural member coils or circulates around a fixed path with an amplitude or diameter much larger than the diameter of the cross section of the structural member itself, the structural member can be wound in distinct visible coils. These coils are discussed in detail in the Spiral Implant Order. In other embodiments, however, a structural member can be wound around a fixed path with an amplitude or diameter less than the cross-sectional diameter of the structural member itself. In this case the resulting geometry
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22/43 of a structural member may appear twisted, but the geometry may not have the different coils seen in the Spiral Implant Order. However, it can be appreciated that although the outermost surface of such a structural member cannot exhibit distinct coils, the central member curve of the structural member has such coils or loops and furthermore has a clear generalized helical geometry.
[0071] Figure 9 is a schematic isometric view of the implant 100 in which the structural members have been removed for clarity. To depict the geometry of the structural members, the central member curve of several structural members is shown. Specifically, the central member curve 520, which corresponds to the geometry of the bone contact member 300, is shown. In addition, the central member curve 504 and the central member curve 506 are shown, which correspond to the geometry of the supporting members. that provide support to the 300 bone contact member.
[0072] As previously discussed, the bone contact member 300 (Figure 5) exhibits a twisted geometry indicative of a spiral or helix. However, since the winding occurs with a much smaller amplitude than the thickness of the bone contact member 300, the geometry of the part can be difficult to discern. The generalized helical geometry of the bone contact member 300 becomes much clearer when the geometry of its central element curve 520 (which is clearly seen in Figure 9) is considered when it revolves around a fixed path 540 (also shown in Figure 9).
[0073] In different embodiments, the winding diameter of a helical structural member can vary.
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23/43
In the exemplary embodiment, a winding diameter 552 of the coils or loops on the central member curve 520 is less than the diameter of the bone contact member 300. In other embodiments, the diameter of the cross section of a bone contact member can be less than the diameter of the corresponding winding of the coils or turns of its central member curve. In such an embodiment, the bone contact member would be configured in a series of different coils.
[0074] A bone contact member may not have a generalized helical geometry over its entire length. Instead, its central limb curve can be configured with a winding segment in which the central limb curve completes several complete turns (three in Figure 9) around a fixed path. Away from the winding segment, its central limb curve may not include turns, twists, etc.
[0075] Although the present modality includes at least one bone contact member with a winding segment that makes one or more complete turns around a fixed path, other modalities can be configured with central limb curves that only make partial turns in around a fixed path.
[0076] Although the description here has focused on the geometry of a single bone contact member 300, it can be appreciated that some or all of the remaining bone contact members in the plurality of structural members 104 may have a similar generalized helical geometry. It can also be appreciated that two different bone contact members may have slightly different geometries, with different bone contact member curves that include
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24/43 variations in the number of windings, the shape of the windings, etc.
[0077] In some embodiments, an implant may include bone contact members that are locally helical for short distances compared to the length, width or height of the implant. For example, implant 100 can be characterized as having bone contact members that are locally helical or spiraled locally, rather than being helical globally. In particular, each bone contact limb of the implant 100 is limited within a single quadrant of the implant 100 and does not cross the transverse plane or the median plane of the implant 100. Thus, a complete turn of the bone contact limbs is performed over very long distances. less than half the length, width or height of the implant. This allows for multiple windings within each quadrant of the implant and also results in the pitch between the windings being less than the length, width or height of the implant. For example, in Figure 9, the central limb curve 520 has a step 529 between windings or adjacent loops less than one third the length of the bone contact member 300. Step 529 is also less than one tenth of the length of the implant 100. This relatively small step size allows for a greater number of regions of the proximal surface along each bone contact member, thus increasing the number of protected fusion zones available from the lower and upper surfaces of the implant 100.
[0078] In some embodiments, the helix-like geometry of the bone contact members provides distinct regions exposed on the upper and lower sides of an implant. Per
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25/43 example, with reference to Figure 5, each bone contact member includes one or more distal regions 360 that can be seen as peaks in the bone contact member along the upper side 130 of the implant 100. In at least some embodiments, these distal regions 360 can be flattened or smoothed to provide a more flat or smooth distal surface on the upper side 130 (and on the lower side 140), thus facilitating contact with the adjacent vertebrae. In other embodiments, a distal surface region may be curved. In some cases, the distal superficial region may have a curvature that corresponds to the curvature of the adjacent superficial regions of the bone contact member. In other cases, the distal superficial region may have a different curvature (for example, more convex) than the adjacent superficial regions of the bone contact member.
[0079] The bone contact members can also include proximal regions 362 that are configured as valleys in the bone contact member along the upper side 130 of the implant 100. While the distal regions 360 can come into contact with the vertebrae during and after the implantation of implant 100, proximal regions 362 can be recessed or spaced from direct contact with the vertebrae, at least before the development of new bone growth.
[0080] As a particular example, Figure 5 includes an enlarged cross-sectional view of a portion of a bone contact member 370 and an underlying support member 390. Specifically, an outwardly facing surface portion 372 of the contact member bone 370 is visible. As used herein, the outward-facing portion of a bone contact member is the portion of the
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26/43 surface of the bone contact member facing a vertebra during implantation or facing outward from the inside of the implant. The outwardly facing surface portion 372 includes a first distal surface region 380, a proximal surface region 382 and a second distal surface region 384. As discussed in more detail below, this local geometry provides a series of protected fusion zones adjacent to each region of the proximal surface, where new bone growth can be protected during initial bone fusion.
[0081] Although bone contact members may have generalized helical geometries, the geometries of the support members can be selected to increase strength and support. In some embodiments, the support members may have a generally solid shape (similar to a tube) and may extend in simple curves from one portion of a body to another. In some cases, the center member curve of a support member can be smoothly curved without local twists, windings or coils.
[0082] Thus, it can be appreciated that, in some modalities, the support members can generally be shorter and their geometry can be more arc-like to improve strength and provide increased support for bone contact members. On the other hand, bone contact members can generally be longer in length and may have a less arched shape in relation to support members, as bone contact members need to extend as far as possible over the upper / lower sides of an implant to provide contact with the vertebrae.
Petition 870190120940, of 11/21/2019, p. 31/69 / 43 [0083] Although some modalities include members of bone contact with generalized helical geometries and support members with arc type geometries, in other modalities any structural member can be configured with any type of geometry. For example, in another embodiment, one or more support members may have a generalized helical geometry that creates protected fusion zones along the support members. In yet another embodiment, one or more members of bone contact may have an arc-like geometry.
[0084] In different modalities, the fixation between a support member and a bone contact member can occur in several places. In some embodiments, a support member can be attached close to a distal surface region along the outer surface of a bone contact member. In other embodiments, a support member can be attached close to a region of the proximal surface along the outer surface of a bone contact member.
[0085] In some embodiments, each support member is configured to connect to a corresponding bone contact member at an adjacent (or underlying) location to a proximal superficial region of the bone contact member. For example, as shown in Figure 5, a fixation region 189 of support member 390 is attached to bone contact member 300 at a location corresponding to the proximal surface region 382 of bone contact member 300. Likewise, all others implant support members 100 attach to one or more bone contact members only at locations corresponding to the proximal surface regions.
[0086] This configuration provides fusion zones
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28/43 protected areas covering the space immediately adjacent to the proximal regions. Protected fusion zones are locations along the upper / lower surfaces of an implant where new bone growth can be partially protected from forces applied to bone contact members by adjacent support members or directly from a vertebra.
[0087] When configuring one or more bone contact members with at least one helical portion, the bone contact member can provide one or more protected fusion zones on the upper and lower sides of an implant. These protected fusion zones cover the space immediately adjacent to the proximal regions of the bone contact members. The indented spaces provided by the proximal regions allow pockets of new bone growth adjacent to the initial fusion that can occur in the distal regions. In addition, since the support members are attached close to the proximal superficial regions, and not to the distal regions of the surface, the forces applied to the bone contact members by the support members or by a vertebra can be directed away from the fusion zones. protected, thereby minimizing disruption to new bone growth.
[0088] Figure 10 is a schematic top-down view of an implant 600, according to an embodiment. Referring to Figure 10, the implant 600 includes the body 601 comprising the peripheral structure portion 602, the peripheral structure portion 604, the peripheral structure portion 606 and the peripheral structure portion 608. In addition, the body 601 comprises the ring 609 that defines a central opening 650.
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29/43 [0089] For reference purposes, central opening 650 (and ring 609) defines a radial direction 599 and a circumferential direction 598. Here, radial direction 599 extends outwardly from a center of the central opening 650, while the circumferential direction 598 is an angular direction that is perpendicular to the radial direction 599.
[0090] In different modalities, the orientation of the bone contact members and / or support members can vary. In some embodiments, the bone contact members can be oriented radially away from the center of an implant. In some embodiments, the support members can be oriented in a circumferential (or angular) direction that revolves around the center of an implant. In other modalities, however, the bone contact members can be oriented in a circumferential direction while the support members can be oriented in a radial direction. In still other embodiments, one or more structural elements can be oriented in directions orthogonal to the length and / or width of an implant, rather than in radial and / or circumferential directions.
[0091] The implant 600 also includes plurality of bone contact members 630 and plurality of support members 632. As seen in Figure 10, plurality of bone contact elements 630, which includes the first bone contact member 611, second member of bone contact 612, third bone contact member 613 and fourth bone contact member 614 each can extend in radial direction 599 (that is, externally from central opening 650 and ring 609). For example, the first bone contact member 611 extends radially from ring 609 to the portion
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30/43 of peripheral structure 602. The second bone contact member 612 also extends radially from the ring 609 to the portion of peripheral structure 602, although the second bone contact member 612 has a different angular (or circumferential) position to along circumferential direction 598. In addition, the third bone contact element 613 extends radially from ring 609 to the peripheral structure portion 604. The fourth bone contact member 614 also extends radially from ring 609 to the portion peripheral structure 604, although the fourth bone contact member 614 has a different angular (or circumferential) position along the circumferential direction 598.
[0092] As seen in Figure 10, the plurality of support members 632 is further comprised of the first support member 621, second support member 622, third support member 623, fourth support member 624, fifth support member 625, sixth support member 626, seventh support member 627 and eighth support member 628. Each of these support members can be oriented approximately in the circumferential direction 598. For example, the first support member 621 extends from the frame portion peripheral 606 to its attachment with the second support member 622 along a path 640 which is approximately parallel to the circumferential direction 598. Likewise, the second support member 622 extends from its attachment to the first support member 621 to the peripheral structure portion 608 along a path 642 which is also approximately parallel to the circumferential direction 598. Furthermore, it is clear from Figure 10 that the first
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31/43 support member 621 is approximately perpendicular to the first bone contact member (radially oriented) 611 and that the second support member 622 is approximately perpendicular to the second bone contact member (radially oriented) 612. Likewise, each member remaining support member in the plurality of support members 632 is oriented approximately parallel to the circumferential direction 598 and is also approximately perpendicular to a bone contact member to which it attaches.
[0093] The embodiment of Figure 10 can be characterized as having structural members arranged in a pattern similar to a weft or a weft. In addition, it can be appreciated that although only one side of the implant 600 is shown, an opposite side can also include a central ring and structural members oriented in a web-like pattern.
[0094] This weft-like pattern provides radially oriented structural members (bone contact members) that can help improve strength in several directions simultaneously (ie, longitudinal and lateral directions). This can also help to direct new bone growth from the center of the device (which includes a large central cavity for bone growth) towards the corners and periphery of the device. In addition, the circumferential orientation of some structural members (support members) in this weft pattern also improves the strength of the device in several directions simultaneously and in directions orthogonal to the radially oriented structural members.
[0095] The disposition of the structural members with the body
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32/43 can also be designed to achieve the desired total open volume. As used herein a total volume is the combined volume of any openings between the structural members, any openings in the body or between the structural members and the body. This open configuration can facilitate bone growth in and through the implant. A portion, or substantially all, of the open spaces are optionally filled with a bone graft or bone growth promoting material before or after implant insertion to facilitate bone growth.
[0096] The total volume of open spaces (also simply called open space volume) in any specific implant depends on the overall dimension of the implant, as well as the size and dimension of the individual components within the implant, including structural members, parts of the structure , etc. The volume of open space can vary from about 20% to 80% of the implant volume. In some embodiments, implant 100 may have an open space volume that is between 25% and 80% of the total implant volume. In still other embodiments, implant 100 may have an open space volume that is between 40% and 75% of the total volume of the implant.
[0097] TheFigures 11- 13 illustrate various views schematic in a process in implantation in one implant 600. Referring first The Figures 11-13, O pro access to implantation you can start with the application in one material
bone growth promoter, also known as BGPM, in the implant. As used here, a bone growth promoting material is any material that helps bone growth. Growth promotion materials
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33/43 bone can include provisions that are lyophilized on a surface or adhered to the metal through the use of ligand molecules or a ligand. Examples of bone growth promoting materials are any materials including bone morphogenetic proteins (BMPs), such as BMP-1, BMP-2, BMP-4, BMP-6 and BMP-7. These are hormones that convert stem cells into bone-forming cells. Other examples include recombinant human BMPs (rhBMPs), such as rhBMP-2, rhBMP-4 and rhBMP-7. Still other examples include platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), collagen, BMP mimetic peptides, as well as RGD peptides. Generally, combinations of these chemicals can also be used. These chemicals can be applied using a sponge, matrix or gel.
[0098] Some bone growth promotion materials can also be applied to an implantable prosthesis through the use of a plasma spray or electrochemical techniques. Examples of these materials include, but are not limited to, hydroxyapatite, beta-calcium tri-phosphate, calcium sulfate, calcium carbonate, as well as other chemicals.
[0099] A bone growth promotion material may include, or may be used in combination with, a bone graft or a bone graft substitute. A variety of materials can serve as bone grafts or bone graft substitutes, including autografts (harvested from the patient's iliac crest), allografts, demineralized bone matrix, and various synthetic materials.
[00100] Some modalities may use autograft.
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34/43 autograft provides spinal fusion with calcium collagen scaffolding for new bone growth (osteoconduction). In addition, the autograft contains bone growth cells, mesenchymal stem cells, and osteoblasts that regenerate bone. Finally, the autograft contains bone growth proteins, including bone morphogenic proteins (BMPs), to promote new bone growth in the patient.
[00101] Bone graft substitutes may comprise synthetic materials including calcium phosphates or hydroxyapatites, products containing stem cells that combine stem cells with one of the other classes of bone graft substitutes, and matrices containing growth factors such as INFUSE® (graft bone containing rhBMP-2) from Medtronic, Inc.
[00102] It should be understood that the provisions listed here are not intended to be an exhaustive list of possible bone growth promotion materials, bone grafts or bone graft substitutes.
[00103] In some modalities, BGPM can be applied to one or more external surfaces of an implant. In other modalities, BGPM can be applied to internal volumes within an implant. In yet other modalities, BGPM can be applied to both external surfaces and internally within an implant. As seen in Figures 11-13, a BGPM 700 was placed inside the interior of the implant 600 and also applied to the upper and lower surfaces of the implant 600. In addition, as shown in Figure 11, the BGPM 700 was inserted through (and if extends through) a first window 662 and a second window 664 of
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35/43 implant 600.
[00104] Figures 12 and 13 show schematic views of implant pre-implantation (Figure 12) and post-implantation (Figure 13). Once implanted, implant 600 can be placed between and in direct contact with the adjacent vertebra. Specifically, an upper side 702 of the implant 600 is disposed against the first vertebra 712. Likewise, a lower side 704 of the implant 600 is disposed against the second vertebra 714.
[00105] In different modalities, the implantation methods may vary. In some embodiments, the implant 600 can be attached to an implantation tool 701 (partially seen in Figures 11-12) that is used to drive the implant 600 into the spine. The implantation tool 701 can be any nail, ram, baton or other device that can be hammered, forced or otherwise driven to position the implant 600 between adjacent vertebrae. As mentioned earlier, in some cases, an implant could also be attached to the implant 600 in a fastener receiving portion (i.e., a threaded opening for receiving a threaded shaft from a tool).
[00106] Figures 14-20 represent a schematic sequence of bone growth through the implant 600, including through the central cavity 671 (Figures 14-16), as well as along the upper and lower sides of the implant 600 (Figures 17-20 ).
[00107] Figures 14-16 represent a partial cross-sectional view of the implant 600 just after the implant between vertebra 712 and vertebra 714. Here, BGPM 700
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36/43 fills an interior of the 600 implant and also lines the upper and lower surfaces in contact with the vertebrae.
[00108] Fusion and initial bone growth can occur where the vertebrae are in contact with the BGPM 700. Over time, new bone growth begins to extend along the lower and upper surfaces of the 600 implant, as well as in the cavity central 671, as seen in Figure 15. For example, in Figure 15, the new bone growth region 720 extends from vertebra 712 to central cavity 671 while the new bone growth region 722 extends from vertebra 714 to the central cavity 671. New bone growth regions 726 can also extend into the interior spaces of the implant 600 that are adjacent to the central cavity 671.
[00109] Eventually, as seen in Figure 16, a solid column of new bone growth 724 can form throughout the central cavity 671. This new bone growth in the central cavity 671, together with the new bone growth associated with other regions of the interior and exterior of the implant 600, helps to fuse vertebra 712 and vertebra 714.
[00110] Figures 17-20 represent a schematic sequence of bone growth along an upper surface 675 of implant 600. This new bone growth can occur before, simultaneously or after bone growth through the interior of implant 600, as described above. Although only the upper side is shown in Figures 17-20, it can be appreciated that similar bone growth patterns can occur simultaneously on the lower side of the implant.
[00111] Figure 17 represents an isometric view of the
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37/43 implant 600 inserted between vertebra 712 and vertebra 714, as well as an enlarged view of the upper surface 675. It can be appreciated that, the BGPM 700 is not visible in the enlarged view in Figure 17. This is done for clarity for that new bone growth can be seen clearly as it forms along the surface of the structural members of the 600 implant.
[00112] In Figure 18, new bone growth occurs at various locations on the upper surface 675. Specifically, the new bone growth region 802 occurs within central cavity 671, as described above and represented in Figures 14-16. In addition, new bone growth regions 804 can first form in the protected fusion zones discussed earlier. As disclosed in the Protected Fusion Zone Order, new bone growth regions 804 that occur in protected fusion zones can be protected from local forces between the bone contact members and the vertebrae. This helps to minimize disruption to the new 804 bone growth regions in the protected fusion zones.
[00113] As shown in Figure 19, eventually, new bone growth may extend from the protective fusion zones to the entire length of the plurality of 630 bone contact members. In some embodiments, new bone growth may continue to grow along the surfaces of the plurality of support members 632.
[00114] It can be seen that new bone growth occurs similarly on the lower surface of the 600 implant, as well as extending around the lateral, posterior and anterior sides.
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38/43 [00115] Finally, as seen in Figure 20, the new bone growth region 802 can cover the outside and fill the inside of an implant. At this point, there may be a new bone fusion portion 810 that extends between vertebra 712 and vertebra 714 that fuses the vertebrae.
[00116] In some other modalities, the increase in the volume of bone graft material and eventually new bone growth can be created by the removal of one or more structures arranged within an internal region of an implant. For example, in another embodiment, structures that connect upper and lower rings (for example, first support 226 and second support 228 shown in Figure 3) can be removed. Still other modifications can be made to incorporate any of the structures and / or arrangements, as disclosed in US Publication Number ________, published on ______, currently US Patent Application No. ______, filed on March 13, 2017 and entitled Implant with Helical Held Members, (Attorney Document No. 138-1043) which is incorporated by reference in its entirety.
[00117] Modalities may include provisions for texturing one or more surfaces of an implant. This texture can increase or promote bone growth and / or fusion on the implant surfaces. In some embodiments, the bone contact members may be textured while the support members may not be textured. This helps the initial bone growth to be directed along the bone contact limbs and especially in the protected fusion zones, instead of growing initially between the supporting limbs. In other modalities, however, members of
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39/43 support may include surface textures. In still other embodiments, one or more surfaces of a body can include surface textures.
[00118] In some embodiments, the surface structure of one or more regions of an implant may be rough or provided with irregularities. Generally, this rough structure can be achieved through the use of acid etching, blasting of spheres or grains, spray coating with titanium, titanium sintering spheres or cobalt chromium on the implant surface, as well as other methods. In some embodiments, the roughness can be created by 3D printing a high pattern on the surface of one or more regions of an implant. In some embodiments, the resulting rough surface may have pores of varying sizes. In some embodiments, pore sizes can vary between approximately 0.2 mm and 0.8 mm. In one embodiment, pore sizes can be approximately 0.5 mm. In other embodiments, surface roughness is possible, comprising pore sizes less than 0.2 mm and / or greater than 0.8 mm.
[00119] The modalities can make use of the parts, characteristics, processes or methods of texturing the surface, as disclosed in the Protected Fusion Zone Order.
[00120] The implants for use in the spine have general dimensions adjoined for insertion in the spine, generally between two vertebral bodies. The shape and dimensions of the implant depend on the location where it is inserted. Exemplary heights for implants such as implant 100 and implant 600 include, but are not limited to, 5 mm to 30 mm. Other modalities
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40/43 could have incremental heights of any value in the range between the range mentioned above, most often between 8 mm and 16 mm. Still other modalities can have a height greater than 16 mm. Still other modalities can have a height less than 8 mm. In addition, the horizontal footprint of the implant may vary. Exemplary footprint sizes for any implant modalities include, but are not limited to, 15-20 mm in the anteroposterior direction and 40-60 mm in the lateral-lateral direction. Still other modalities can be configured with other footprint sizes.
[00121] The dimensions of one or more structural members may vary. In some embodiments, a structural member may have a cross-sectional diameter in the range of 0.2 to 3 mm. For structural members with polygonal sections, the dimensions that characterize the polygon (for example, first and second diameters for an ellipse) can vary. As an example, a structural member with an elliptical cross section can have a cross section with a first diameter in the range between 0.2 mm and 3 mm and a second diameter in the range between 0.2 mm and 3 mm. In other embodiments, a structural member can have any other cross-sectional diameter. In addition, in some cases a bone contact member and a support member may have similar cross-section diameters while in other cases a bone contact member and a support member may have different cross-section diameters.
[00122] Modalities can also be provided with several flat / parallel angles (0 degrees), lordotic, and hyper lordotic. In some embodiments, the implant can be configured with an angle of approximately 8 degrees
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41/43 between the upper and lower surfaces. In other embodiments, the implant can be configured with an angle of approximately 15 degrees between the upper and lower surfaces. In yet other modalities, the implant can be configured with an angle of approximately 20 degrees between the upper and lower surfaces. Still other angles possibly include all angles in the range between 0 and 30 degrees. Still other modalities can provide a lordotic angle of less than 8 degrees. Still other modalities can provide a hyper lordotic angle of more than 20 degrees. In at least some modalities, the lordotic angle of the implant is realized through the geometry of the central portion of the keel and the portion of the lateral structure (posterior or anterior).
[00123] The various components of an implant can be manufactured from biocompatible materials suitable for implantation in a human body, including but not limited to, metals (for example, titanium or other metals), synthetic polymers, ceramics, and / or their combinations, depending on the application and / or preference of a doctor.
[00124] Generally, the implant can be formed from any suitable biocompatible and non-degradable material, with sufficient strength. Typical materials include, but are not limited to, titanium, biocompatible titanium alloys (for example, yTitanium Aluminides, TÍ6-A14V ELI (ASTM F 136 and F 3001) or TÍ6-A14-V (ASTM F 2989, F 1108 and ASTM F 1472)) and inert, biocompatible polymers, such as polyether ether ketone (PEEK) (for example, PEEKOPTIMA®, Invibio Inc and Zeniva Solvay Inc.). Optionally, the implant contains a radiopaque marker to facilitate the
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42/43 preview during image.
[00125] In different modalities, the processes for making an implant can vary. In some modalities, the entire implant can be manufactured and assembled through reading / CNC machining, injection molding, casting, insertion molding, coextrusion, pultrusion, transfer molding, over molding, compression molding, three-dimensional printing (3- D) (including direct metal laser sintering and electron beam fusion), dip coating, spray coating, powder coating, porous coating, milling from a solid material and combinations thereof. In addition, the modalities can make use of any of the characteristics, parts, assemblies, processes and / or methods disclosed in the Rolled Implant Order.
[00126] Although several modalities have been described, the description is intended to be exemplary, rather than limiting, and it will be evident to those skilled in the art that many more modalities and implementations that are within the scope of the modalities are possible. Although many possible combinations of features are shown in the attached figures and discussed in this detailed description, many other combinations of the disclosed features are possible. Any feature of any modality may be used in combination with or replaced by any other feature or element in any other modality unless specifically restricted. Therefore, it will be understood that any of the features shown and / or discussed in the present disclosure can be implemented together in any suitable combination. Therefore, the modalities do not
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43/43 must be restricted except in light of the appended claims and their equivalents. In addition, various modifications and changes can be made within the scope of the attached claims.

权利要求:
Claims (19)
[1]
1. Implant, characterized by the fact that it comprises:
a body including a ring, the ring further defining an opening;
the body defining a transverse plane that divides the implant into an upper half and a lower half;
the ring defining a radial and a circumferential direction;
a bone contact member attached to the ring, wherein the bone contact member extends radially from the ring; and a support member attached to the bone contact member in a fixation region, in which the support member extends in the circumferential direction.
[2]
2/5 has a generally helical geometry.
2. Implant, according to claim 1, characterized by the fact that, in the fixation region, the support member is disposed closer to the transverse plane than the bone contact member is to the transverse plane.
[3]
3/5 is arranged in the upper half of the implant, and in which the implant has another weft-shaped pattern formed by bone contact members and support members arranged in the lower half of the implant.
3. Implant, according to claim 1, characterized by the fact that the ring is located in a central region of the implant.
[4]
4/5 the first bone contact member is at the transverse plane in the first fixation region.
4. Implant, according to claim 1, characterized by the fact that the body includes a portion of peripheral structure that defines an external periphery of the implant; and wherein the bone contact element extends from the ring to the peripheral structure portion.
[5]
5/5 plurality of bone contact members extends radially away from the central region of the body.
5. Implant, according to claim 1, characterized by the fact that the bone contact member
Petition 870190090788, of 12/09/2019, p. 15/20
[6]
6. Implant, according to claim 1, characterized by the fact that the bone contact member is a first bone contact member, and in which the implant also includes a second bone contact member, a third bone contact member and a fourth member of bone contact.
[7]
7. Implant, according to claim 6, characterized by the fact that the first bone contact member and the second bone contact member extend from a first side of the ring to a first end of the implant, and in which the third bone contact member and the fourth bone contact member extend from a second side of the ring to a second end of the implant.
[8]
8. Implant, according to claim 7, characterized by the fact that the implant further includes a plurality of support members, in which each of the plurality of support members is attached to at least one bone contact member, and in that each of the plurality of support members extends in the circumferential direction.
[9]
9. Implant, according to claim 8, characterized by the fact that the first bone contact member, the second bone contact member, the third bone contact member, the fourth bone contact member and the plurality of support members are arranged in a weft-shaped pattern.
[10]
10. Implant, according to claim 9, characterized by the fact that the weft-shaped pattern
Petition 870190090788, of 12/09/2019, p. 16/20
[11]
11. Implant, characterized by the fact that it comprises:
a body;
the body defining a transverse plane that divides the implant into an upper half and a lower half;
a first bone contact member attached to the body and arranged in the upper half of the implant;
a first support member attached to the first bone contact member, the first support member being disposed within the upper half of the implant;
a second bone contact member attached to the body and disposed in the lower half of the implant;
a second support member attached to the second bone contact member, the second support member being disposed within the lower half of the implant; and wherein an end of the first support member is attached to an end of the second support member.
[12]
12. Implant, according to claim 11, characterized by the fact that the first support member and the second support member are fixed adjacent to the transverse plane.
[13]
13. Implant, according to claim 11, characterized by the fact that the first support member is attached to the first bone contact member in a first fixation region, and in which the first support member is arranged closer to the plane transversal than
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[14]
14. Implant, according to claim 13, characterized by the fact that the second support member is attached to the second bone contact member in a second fixation region, and in which the second support member is arranged closer to the plane transverse than the second bone contact member is to the transverse plane in the second fixation region.
[15]
15. Method, according to claim 11, characterized by the fact that:
the implant includes a first ring disposed in the upper half, in which the first bone contact element is attached to the first ring;
the implant includes a second ring disposed in the lower half, in which the second bone contact element is attached to the second ring.
[16]
16. Implant according to claim 15, characterized by the fact that the first ring is joined to the second ring by supports that extend through the transverse plane, so that the first ring and the second ring define openings for a central channel that extends through the implant.
[17]
17. Implant, characterized by the fact that it comprises:
a body;
a plurality of bone contact members extending from a central region of the body to a periphery of the body; and in which each of the members of bone contact in the
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[18]
18. Implant, according to claim 17, characterized by the fact that the implant includes three or more bone contact members.
[19]
19. Implant, in wake up with The claim 17, characterized by fact that each one of plurality in contact members bony have a curved geometry. 20. Implant, in wake up with The claim 19, characterized by fact that each one of plurality in
bone contact members have a generalized helical geometry.

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US10449051B2|2019-10-22|Implant with curved bone contacting elements

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BR112019008299A2|2019-10-08|multilayer bone interface lattice implant

同族专利:

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公开号 | 公开日

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US20180256351A1|2018-09-13|

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US11213405B2|2022-01-04|

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US10512549B2|2019-12-24|

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JP2020509861A|2020-04-02|

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US20200229940A1|2020-07-23|

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WO2018169873A1|2018-09-20|

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法律状态:
2021-10-19| B350| Update of information on the portal [chapter 15.35 patent gazette]|

优先权:

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申请号 | 申请日 | 专利标题

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US15/457,470|US10512549B2|2017-03-13|2017-03-13|Implant with structural members arranged around a ring|

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PCT/US2018/022024|WO2018169873A1|2017-03-13|2018-03-12|Implant with structural members arranged around a ring|

---