• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    SAFE PACKAGING FOR CHILDREN. It is a package that includes a container and a cover sheet, the container having a first section and a second section connected to a breakaway gasket (30), the first section including a cavity, and the cover sheet. cover is adhered to at least a portion of the first section and at least a portion of the second section, and the cover sheet covers the cavity. The first section or the second section is adapted to pivot at a fulcrum (10) between the cover sheet and the gasket to help break the breakaway gasket to separate the first section and the second section and allow removal of the cover sheet. roof.
    公开号:BR112015029098B1
    申请号:R112015029098-1
    申请日:2014-05-20
    公开日:2021-05-18
    发明作者:Harry S. Sowden；Gerard P. Mcnally；R. Scott Shorts
    申请人:Johnson & Johnson Consumer Inc；
    IPC主号:
    专利说明:

    REFERENCE TO RELATED DEPOSIT REQUESTS
    [001] This application claims priority of the filing benefits of U.S. Provisional Application Serial No. 61/825652, filed May 21, 2013; U.S. provisional application No. 61/825704, filed May 21, 2013; U.S. provisional application No. 61/825740, filed May 21, 2013; U.S. provisional application No. 61/825660, filed May 21, 2013; U.S. provisional application No. 61/825691, filed May 21, 2013; and U.S. Provisional Application No. 61/825,669, filed May 21, 2013; the contents of which are incorporated herein by reference in their entirety. BACKGROUND OF THE INVENTION FIELD OF THE INVENTION
    [002] The present invention relates to packaging for products. More particularly, the present invention relates to tamper resistant and child-safe packaging for pharmaceutical and/or consumer products. BACKGROUND
    [003] Product packaging comes in many shapes and formats. A wide variety of blister packs for packaging a variety of consumer products are available in the art. Such blister packs are typically formed of a transparent layer (the "blister") coupled (preferably sealed or otherwise bonded) to a backing layer. The blister pack has a reservoir or cavity or other type of deformation formed therein so that, upon coupling the blister to the backing layer, a compartment or envelope is formed to hold or contain a desired product. The product cavity(s) can be accessed by extracting the support layer from the packaging, in order to expose the cavity and the product in it, or in order to expose a layer of breakable/push-open support below the cavity through which the product can be pushed when pressure is exerted on the blister and article (a "peel-and-push" blister pack). Alternatively, the cavity(s) can be accessed by tearing the edge of the package towards such cavity(s) (blister packaging with "tear access"). To facilitate tearing, an initial notch or slit can be provided.
    [004] For the packaging of pharmaceutical and drug products, the blister-type packaging is often used for dosage of individual units or unit doses. This type of packaging is also designed to provide child safety or child protection to prevent children from easily accessing the medicine/product kept inside. However, the package also needs to be designed to allow adults to access the medication contained in the package.
    [005] A common use of blister packs is for packaging solid dose drugs or pharmaceuticals (e.g., tablets, capsules, pills and the like; henceforth, "medicines" as a matter of convenience and not intended to limit ) or consumer products. Typically, such packaging is desirable for carrying individual/unit doses of medicine and may allow a greater level of portability than other types of packaging (e.g. bottles). Like typical blister packs, drug blister packs generally allow for moderately easy viewing of their contents. Such easy viewing can make a young child want to access the product. The Consumer Product Safety Commission has established rules governing which products require special packaging and special regulations for such special packaging in the Poison Prevention Packaging Act of 1970, set out in Code of Federal Regulations, Title 16, Part 1700. "Special packaging", commonly called child-safe packaging or CR (Child Resistant), it is defined at 16 CFR sctn.1700.1 (b)(4) as "packaging that is designed or constructed to be significantly difficult for children under 5 years of age to open or obtain a toxic or harmful amount of the substance contained therein, within a reasonable period of time and not difficult for normal adults to use properly, but it does not mean that all such children cannot open or obtain a toxic or harmful amount within a reasonable period of time." Products that require special packaging include all prescription drugs and over-the-counter drugs and a variety of other substances that are harmful if handled, used, or ingested. Child-safe blister packs are also desirable for packing any other type of article that is not safe for a child, such as medical instruments, sharp objects, or substances that can cause addiction (eg caffeine, nicotine, etc.).
    [006] A variety of ways to form a child-safe blister pack are known in the art. For example, a peel-and-pull blister pack generally requires sufficient cognitive skills to make the pack safe for children. "Tear access" blister packs can be formed of a tear-resistant material that is nearly impossible to tear, unless the material is weakened (such as through perforations) and a minimal amount of force, generally greater than a child's capacity is used. However, child-safe blister packs need to take into account the needs of adults who must access their contents. In particular, the child-safe blister pack must be designed so as to allow elderly and physically disabled adults to readily open the pack. If the tear strength of a child-safe tear-access blister pack is reduced so that an elderly or physically disabled adult can readily open it, then there is a risk that a child might also open such a pack.
    [007] Additional resources (for example, that require folding, tearing or detachment to gain access to the cavity contents of the product) may be needed to add another step beyond the cognitive ability of young children. As such, high tear strength may not be necessary for a blister pack with tear access to still qualify as safe for children. For example, a tear-initiating notch (generally required in tear-resistant blister packs to initiate tearing) may be inaccessible unless the blister card is folded, as described in U.S. patent Nos. 3,809,220 by Arcudi and 5,511,665 by Dressel et al. Alternatively, it is possible that a portion of the blister card may have to be removed first to allow tearing of the package to gain access to the contents of the blister, as described in U.S. Patent No. 6,422,391, to Swartz. The requirement to tear at a specific location on the blister pack also elevates the cognitive ability required to open the pack, as requiring initial tearing through a blister with peripheral tear, as described in U.S. Patent No. 6,036,016, to Arnold. Another added step that raises the cognitive capacity required to open the blister pack, in addition to that possessed by a typical child, may be the requirement to manipulate the drug in the blister before the blister pack breaks for access to the drug, as described in US Patent Nos. 4,371,080 to Haines and 5,529,188 to Coggswell.
    [008] There remains a continuing desire in the industry to enhance the child-safe features of tear-access blister packs to improve consumer-friendly conditions as well as ease of opening by adults, including elderly and physically disabled adults. SUMMARY OF THE INVENTION
    [009] The present invention is directed to a package comprising a container that has a first section and a second section connected in a breakaway joint, the first section comprising a cavity; and a cover sheet, wherein the cover sheet is adhered to at least a portion of the first section and at least a portion of the second section, and the cover sheet covers the cavity; the first section or the second section being adapted to pivot at a fulcrum between the cover sheet and the gasket, to help break the breakaway joint to separate the first section and the second section, so that, upon rupture, the first section and second section are still adhered to the cover sheet and the second section serves as a handle to remove the sheet from the first section to expose the cavity.
    [0010] The present invention is also directed to a card comprising at least one package, the package comprising a container that has a first section and a second section connected in a breakaway joint, the first section comprising a cavity; and a cover sheet, wherein the cover sheet is adhered to at least a portion of the first section and at least a portion of the second section and the cover sheet covers the cavity; the first section or the second section being adapted to pivot at a fulcrum between the cover sheet and the gasket, to help break the breakaway joint to separate the first section and the second section, so that, upon rupture, the first section and second section are still adhered to the cover sheet and the second section serves as a handle to remove the sheet from the first section to expose the cavity. BRIEF DESCRIPTION OF THE DRAWINGS
    [0011] The detailed description will be better understood in conjunction with the accompanying drawings, in which similar reference characters represent similar elements, as follows: Figure 1 illustrates a lever arm beginning to flex; Figure 2 illustrates a more fully flexed lever arm; Figure 3A and Figure 3B illustrate a basic embodiment of a container with a tear-off seal; Figure 4 illustrates a lever arm and a fulcrum as part of a package; Figure 5 is a top view of an embodiment of the present invention. Figure 6A and Figure 6B show a side view of a package that has a contact point that can be used to break a tear gasket; Figure 7 shows a carton with a handle flexed upwards above the plane of the carton; Figure 8 shows a package showing the second section detached from the first section; Figure 9 shows another embodiment of the invention; Figure 10 shows another embodiment of the invention; Figure 11 is a perspective view of a carton having openings in the first section and the second section; Figure 12A and Figure 12B illustrate the pivoting action of an embodiment of a package of the invention; Figure 13A and Figure 13B illustrate the pivoting action of one embodiment of a package of the invention; Figure 14A and Figure 14B illustrate the pivoting action of one embodiment of a package of the invention; Figure 15 is a bottom view of a package featuring a bait feature of the present invention; Figure 16 is a perspective view of the package of Figure 10; Figure 17 is a top view of the package of Figure 10; Figure 18A and Figure 18B show a package with a bent bending in an upward direction and in a downward direction; Figure 19 illustrates a side view of one embodiment of a cavity. Figure 20 illustrates another embodiment of a side view of a cavity; Figure 21 shows packages stacked on top of each other; Figure 22 shows a cover sheet with a graphic sign and three-dimensional text; Figure 23 is a bottom view of a pack having eight individual packs, one pack having been separated from the pack; and Figure 24 is a top view of a pack having eight individual packs, one pack having been separated from the pack. DETAILED DESCRIPTION OF THE INVENTION
    [0012] The present invention provides a package that is particularly suitable for limited access or child-safe applications, although the package of the present invention need not necessarily rise to the level of an approved "child-safe" package. The child-safe features of the package of the present invention are based on requiring a level of cognitive abilities to open the package beyond those a child possesses (at least the age specified in Title 16 of CFR, Part 1700), but within those of elderly or physically disabled adults.
    [0013] A package formed in accordance with the principles of the present invention requires multiple steps so that access to the product contained in the cavity, even more preferably, does not require a high degree of strength or resistance to be opened. In one embodiment, the package of the invention is opened by applying a force sufficient to break a breakable gasket, which allows the cover sheet, sealed to at least a portion of the package, to be removed. Without breaking the breakaway joint, it is difficult for any user to remove the cover sheet. The additional step of breaking the breakaway joint creates a greater level of complexity, which makes the packaging safer for children.
    [0014] The present invention is directed to a package comprising a container and a cover sheet. Desirably, the container has a first section and a second section connected at a breakaway joint, the first section comprising a cavity. The cover sheet is adhered to at least a portion of the first section and at least a portion of the second section, and the cover sheet covers the cavity. The cover sheet may be adhered to the first and/or second section in such a way that it cannot be removed without further action being taken, for example the cover sheet may be perimeter sealed around the first and second sections. In this mode, the first section or second section is adapted to articulate a point of engagement (hereafter referred to as "fulcrum") between the first and second sections to help break the breakable joint to separate the first section and the second section. Additionally, upon rupture, the first section and second section are still adhered to the cover sheet, and the second section serves as a handle to remove the sheet from the first section to expose the cavity.
    [0015] The container includes a first section and a second section that are connected by a tear-off joint. In one embodiment, a portion of the first section extends beyond the plane of the breakaway joint so as to be inside or outside the periphery of the second section. In one embodiment, a portion of the second section extends beyond the plane of the breakaway joint so as to be within or outside the periphery of the first section.
    [0016] The container can be made of a semi-rigid or rigid material. Suitable materials include, but are not limited to, polypropylene, polyethylene, high density polyethylene (HDPE), polyvinyl chloride, polyvinylidene chloride (PVDC), fluorinated-chlorinated resin, fluoropolymer and mixtures thereof. In one embodiment, the container is desirably produced from a recyclable material.
    [0017] The physical properties of these materials are ideally suited for use in the packaging of the invention. For example, polypropylene (PP) and high density polyethylene (HDPE) are materials that are very strong in both tensile and compression, but are somewhat weak when shear forces are applied. They are not brittle and will not crack as easily as polyvinyl chloride (PVC), although materials such as PVC can be used as desired. Additionally, additives can be added to improve the material's desired properties or characteristics. Suitable additives include, for example, dyes/toners, clarifiers, stabilizers/inhibitors/UV blockers, oxygen scavengers, desiccants and antimicrobials. In addition, fluorinating agents to prevent chemical permeation, weight loss, odor emission, and loss of taste and aroma can be added to the semi-hard material.
    [0018] In the present invention, the first section or second section of the container functions as a lever, which pivots around a hitch point disposed between the side walls of the first and second sections (the "fulcrum"). A fulcrum is basically a support or fixed point where a wall of the first section is in contact with a wall of the second section. The force arm is the part of the lever to which some type of force is applied. The force arm is defined as the distance from the fulcrum to the point where force is applied. The resistance arm is the part that moves against a resistance. The resistance arm is defined as the distance from the fulcrum to the point where the resistance is concentrated, eg the breakaway joint.
    [0019] The first section of the container includes a cavity for retaining the product. Optionally, the cavity can be surrounded by a ferrule.
    [0020] The cavity retains a product and protects the product. The cavity can be shaped to conform to the product it is to contain. In a preferred embodiment, the cavity is circular in shape. In another preferred embodiment, the cavity is designed to contain a drug. The cavity may also be designed to provide or deliver a unit dose of a drug. The cavity can be of sufficient strength to securely contain a component without the risk of crushing or rupture through packaging, application and, ultimately, use of the product by a user.
    [0021] For added protection, the cavity may be designed at an angle along the interior of the cavity side walls to securely retain the product in the cavity, allowing little or substantially no movement of the product. In the embodiment shown in Figure 19, for example, a large portion of the sidewall 52 of the cavity 50 is at an angle of about 0° to about 20° with respect to a line perpendicular to the plane of the lidding sheet 40. Preferably , the angle of the sidewall 52 is from about 0° to about 10° and more preferably from about 0° to about 5° with respect to a line perpendicular to the plane of the cover sheet 40.
    [0022] The container can be designed and manufactured according to the needs and purpose of the packaging. For example, the container can have a uniform thickness throughout the package. Or the container can be produced with varying thickness in different portions of the package. In one embodiment, cavity 50 has a sidewall 52 and a bottom 54, the thickness of the bottom 54 being greater than the thickness of the sidewall 52. See Figure 20. In another embodiment, the thickness of the bottom 54 of cavity 50 is greater than 80% of the thickness of sidewall 52.
    [0023] In one embodiment, as seen in Figures 20 and 21, a shoulder 56 may be added along the sidewall 52 to reinforce the cavity 50, thereby increasing the crush resistance force of the cavity 50. , the inclusion of shoulder 56 along side wall 52 of cavity 50 allows the package to be stacked on top of one another. The ability to stack multiple packages, especially when the package is manufactured in a carton configuration, where multiple packages are linked together, for example a 2 by 4 configuration (for a total of 8 individual packages), can be a feature Useful for storage purposes or for manufacturing purposes. See Figure 21.
    [0024] Optionally, the container can have one or more cavities, i.e. multiple cavities.
    The cover sheet covers the cavity and is typically sealed to the cavity itself, the container and/or a ferrule which may surround the cavity. An adhesive and/or heat treatment (eg, thermobonding) is used to seal the cover sheet to the container. Preferably, the cover sheet is formed from a tear and puncture resistant material such as a tear resistant lamination. Preferably, the material of the cover sheet is selected so that it is compatible with the material of the container, such as with regard to heat-sealability. Additionally, as with the container, the cover sheet needs to be compatible with the product contained in the cavity. Barrier properties, UV protection, and other characteristics (such as, but not limited to, those that contribute to product stability) can be important considerations when selecting cover sheet material. Suitable materials include, for example, PET, a PET sheet lamination, or some other oriented polypropylene lamination. If desired, the cover sheet material can be substantially rigid to retain the full hardness of the package.
    [0026] Additionally, the cover sheet can be formed of a flexible material, a rigid material or a textured material. Cover sheet tearability can be an important factor in the selection of cover sheet material. Generally speaking, for child safety, the cover sheet material is selected to be at least somewhat tear resistant. The degree of tear strength is based on the level of child safety desired or required for the packaging. Sealing the container to the cover sheet can further enhance the overall tear strength of the package.
    [0027] The cover sheet covers and seals at least a portion of the top surface of the container. For example, the cover sheet covers and seals about at least 20% of the surface of the container that is covered and sealed. Preferably at least about 30%, more preferably at least 50% and even more preferably at least 60% of the surface of the container is covered and sealed.
    [0028] In one embodiment, the cover sheet is sealed around the perimeter of at least a portion of the container. In another embodiment, the cover sheet is sealed around a portion of the perimeter of the cavity. It may be particularly desired for the lidding sheet to be sealed in such a way that there are no loose ends or flaps of the lidding sheet that can be accessed by a user, thus requiring the breakage of the tear gasket to peel off the lidding sheet.
    [0029] In pharmaceutical or drug packaging, the cover sheet may include a first layer of white polyester, a second layer of adhesive, a third layer of sheet and a fourth layer of heat seal. As discussed earlier, the cover sheet must be strong and provide excellent safety for children.
    [0030] In some applications, the cover sheet may include features or materials such as a heat sealable layer, aluminum foil, adhesive/bonding layers, primer, polyester, paper, metallized film, polyethylene, paint, chloride polyvinyl (PVC), polypropylene (PP), biaxially oriented polypropylene (BOPP), ethylene vinyl alcohol (EVOH) and combinations thereof.
    [0031] Reference will now be made to the Figures, which provide a greater understanding of the various embodiments of the present invention.
    [0032] Figure 1 illustrates the basic concept of a fulcrum lever arm of the present invention. In Figure 1, a surface 5 of a package with a cover sheet 40 on an upper portion of the surface 5 is being flexed. Bending results in the lidding sheet 40 (e.g., the lidding material) bulging, wrinkling or puckering at the bending point 7. Due to the strength and adhesion of the lidding sheet, if the lidding sheet has to be shirred down , the package will not open properly. As the cut geometry closes and edges meet (for example, by flexing a flap element), a D-D pivot line is created. Bending further increases the leverage around the D-D fulcrum line until the tension increases to the point of breaking a breakable joint. This is the force that breaks the breakaway joint that connects the first section and the second section. The mechanical advantage that is created to break the frangible element/zone is defined by the ratio between dimension "B" divided by "A", where "A" is the distance from the fulcrum to the distal tip of the breakable joint, and " B" is the length of the lever applied against the fulcrum. As such, this leverage ratio is a measure of the force required to open the package and is a multiplier force. A typical human being would not be strong enough to open a package without first applying force to separate a breakable joint. This can be adjusted or adapted as desired. The smaller the ratio, the more difficult it is to open. Conversely, the higher the ratio, the easier it is to open. In the present invention, the lever ratio is the distance from the fulcrum to a distal point of the breakable joint compared to the length of a lever defined by the first section or second section. In one modality, the leverage ratio is 1:1 or greater than about 1:1. In another embodiment, the leverage ratio is 2:1 or greater than about 2:1. In yet another embodiment, the leverage ratio is 4:1 or greater than about 4:1. In yet another modality, the leverage ratio is 6:1 or greater than about 6:1. The mechanical advantage/lever ratio of the fulcrum lever arm can be adjusted to provide a desired level of strength to make the package safe for children.
    [0033] In another embodiment, the distance from the breakable joint to the fulcrum is at least five times less than the distance from the distal tip of the second section from the joint.
    [0034] Figure 2 illustrates a breakable joint, where the leverage ratio was insufficient, resulting in a joint that is extended but not broken. In this figure, a leverage ratio greater than a "Q" dimension of stretch break is selected. The surface 5 of a package is flexed upwards, and the point of contact (fulcrum) between the first section and the second section can be seen at the fulcrum 10. In doing so, failing to choose a proper leverage ratio leads to a package that won't open. In such a situation, the "Q" stretch of the polymer causes the flap to flex too much. In this illustration, the leverage ratio is driven by substrate thickness "T". Polymers such as PP and HDPE are very elastic before breaking under tensile forces. These polymeric materials will stretch significantly before the material breaks. This implies that "Q" will have a large value and that the force required to break the joint needs to be taken into account.
    [0035] Figures 3A and 3B show an embodiment of a container that has a tear-off joint 30 that connects a first section 1 and a second section 2. As can be seen, the tear-off joint 30 can include regions where there is no connection between the two sections and regions where there is a connection between the two sections. In Figure 4, lever arm 20, fulcrum 10, breakaway gasket 30 and cover sheet 40 are shown. The lever arm and fulcrum 10 are located between the breakaway gasket 30 and the cover sheet 40 in a package. In use, fulcrum 10 acts as a fulcrum when it contacts lever 20 and a force is exerted on lever 20. As can be seen, fulcrum 10 is any configuration that results in a first section 1 and second section 2 come into contact with each other at a defined point or line.
    [0036] As described above, a feature of the present invention includes a breakaway joint 30 that connects the first section 1 and the second section 2. The breakaway joint 30 is an area of weakness that ruptures when sufficient force is applied against the joint 30 To break the joint 30, the first and/or second sections (1, 2) are moved at an angle to each other, such that the joint is 30 is separated. Sufficient pulling forces applied against the breakaway joint 30 will separate the joint. The force required to break the tear gasket 30 can be adjusted by marking, notching or drilling the tear gasket 30. Alternatively, the tear gasket 30 can be formed having (i) a specific thickness and/or shape, and/or (ii) at least one attachment point (preferably at least two points), which affects the force required to break the breakaway joint 30. In one embodiment, the breakaway joint 30 can be notched to have a "V" point pointing in the opposite direction to the cover sheet 40 or cover material. In one embodiment, the joint 30 ruptures due to excessive tensile forces applied to the breakaway joint 30.
    [0037] As can be seen in Figure 4, the cover sheet 40 extends between the first section 1 and the second section 2 on a surface opposite the tearable gasket 30. covering 40, a user will have difficulty flexing the first and second sections in a direction opposite to that necessary to break the joint 30.
    [0038] Figure 5 is a perspective view from below of an embodiment of the packaging of the invention, the first section 1 of the packaging having a spoon-shaped configuration, including the cavity 50 and the handle 60. The second section 2 of the packaging is connected to first section 1 by breakaway joint 30. In the embodiment shown, first section 1 and second section 2 are secured to cover sheet 40. Second section 2 includes optional ribs 85. In one embodiment, handle 60 includes a or more reservoirs or cavities that are capable of housing a product. Noticeably, the shape of the first section 1 resembles that of a spoon, which can be used by a user to assist in drug delivery without having to first take the drug out of the cavity by hand.
    [0039] Figure 6A shows a side view of a package showing an embodiment of the invention, where a second section 2 of a package is flexed in a direction perpendicular to the tear joint 30, which connects the second section 2 to the first section 1 of the packing. As can be seen, there is a gap between the breakaway joint 30 and the cover sheet 40, which allows movement of the first and second sections (1,2) in only one direction (for example, in a direction such that the fulcrum 10 is formed by engaging the first section 1 and second section 2). Note that during the "rupture" step, there is a hitch point between the first section 1 and the second section 2 at fulcrum 10. In Figure 6B, the second section 2 was moved with sufficient force to break the breakaway joint. 30. The joint breaks, (eg, separates) due to excessive force applied to the breakable joint as a result of the lever and fulcrum 10.
    [0040] Another aspect of the invention is that the tensile strength limit of the cover sheet, eg laminated mylar structure, allows the package to be flexed in only one direction.
    [0041] Figure 7 shows a package of the invention in which the tear gasket 30 is torn and the cover sheet 40 has bent or creased (70). Once the tear gasket 30 is broken, the second section 2 can be used as a handle (designated as 80) to assist in removing the cover sheet 40 from at least a portion of the first section 1. In the embodiment of Figure 7, separating the second section 2 from the first section 1 reveals that the first section 1 has a spoon-shaped configuration.
    [0042] Figure 8 shows a package being opened, the gasket being broken, and the handle 80 and cover sheet 40 being separated from the first section 1. As noted above, the handle 80 is formed from of the second section 2 when the breakaway joint 30 is torn. The resulting configuration of section 1, after removal of section 2, shows a spoon-shaped configuration that includes a handle 60 and cavity 50. Optional rib structures 65, 85 can be included in handle 80 and handle 60. of rib 65, 85 help to reinforce the packaging. In consumable applications, a spoon-shaped package advantageously helps maintain the integrity of a frangible product because it allows the user to consume the product directly outside the package and requires less handling on the part of the user.
    [0043] In Figure 9, an alternative embodiment of an open package is shown, after the rupture of the gasket and where handle 80 has been separated from the bottom of the package. The handle 80 includes ribs 65. In this embodiment, it may be noted that there is an additional third section 6, in addition to the first section 1 and second section 2. This third section 6 may include a breakaway joint (not shown) to allow a right-handed or left-handed user access cavity 50, or third section 6 may be a bait section that is non-breakable.
    [0044] Figure 10 illustrates another modality of a package with handle 80 and cover sheet 40, where the handle 80 and cover sheet 40 are flexed upwards, above the plane of the package. In this mode, it can be noted that section 2 (which results in handle 80) extends laterally along the sides of section 1. In addition, Figure 10 shows multiple lines in various directions, which can act as decoy lines, which are not breakable by a user.
    [0045] Notably, the packages shown in Figure 9 and Figure 10 are spoon-shaped.
    [0046] As can be seen from Figure 11, an optional feature that may be included in the package is one or more openings 68 formed in the first section 1 and/or the second section 2 of the container. The opening(s) extends through the bottom of the first section 1 and/or second section 2, and exposes a surface of the cover sheet, which is adhered to the container.
    [0047] Apertures 68 can provide several beneficial features. In one embodiment, the opening(s) 68 aid(s) in locating the positioning of the thumb and/or finger on the package. In another embodiment, the opening(s) may help to open the package. For example, an object can be inserted into an opening 68 to break or dislodge the cover sheet, which can then be peeled off to expose the cavity.
    [0048] In the embodiment shown in Figure 11, the second section 2 and the handle 60 include openings 68. The openings 68 may be hidden by the cover sheet 40. In this specific embodiment, the rib structures 65, 85 help to define openings, 68 and provide structural strength to the container 3, and the first section 1 and second section 2 are gradually tapered towards the ends. The openings and gradual taper are optional ergonomic features that guide the user in securing the package for opening.
    [0049] In Figures 12A to 12B, an optional configuration for a package is shown. In this embodiment, container 3 is shown with first section 1 and second section 2. First section 1 includes cavity 50 and handle 60. Two breakaway joints 30 connect first section 1 to second section 2. It will be noted that handle 60 extends beyond the plane of breakaway joint 30. Second section 2 encircles a portion of handle 60. In Figure 12B, second section 2 has been flexed upward to break breakable joints 30, thus separating second section 2 of the first section 1 (obviously, if a cover sheet is adhered to the first section 1 and the second section 2, the first and second sections can remain attached by the cover sheet). Thus, in this modality, there are two breakable joints with at least two fulcrums. This embodiment demonstrates that the packaging of the present invention may include more than one breakaway gasket and more than one fulcrum and further demonstrates an embodiment where a portion of the first section 1 (eg handle 60) extends beyond the plane of the gasket breakable 30.
    [0050] In Figures 13A to 13B, an alternative embodiment is shown. In this embodiment, the first section 1 completely surrounds the second section 2. That is, the second section 2 is disposed within the periphery of the first section 1. In this embodiment, the first section 1 can be considered as crossing the plane of the tear joint 30. The opening 68 in the second section 2 can be used to locate the positioning of a thumb or finger or to provide the ability to open the cover sheet by inserting an object through the opening 68. In Figure 13B, the second section 2 has been it is moved upwards and breaks the breakaway joint 30. Then, the second section 2 can be used to pull the cover sheet out of the first section 1 so that the interior of the cavity 50 is accessible. Handle 60 remains.
    [0051] The embodiment shown in figures 14A to 14B is similar to the embodiment shown in Figure 13A, except that the first section 1 does not completely surround the second section 2. Instead, a portion of the first section 1 surrounds a portion from the periphery of the second section 2. The first section 1 crosses the plane of the breakaway joint 30 on two sides. Optional opening 68 in second section 2 can also be used to locate the placement of a thumb or finger. In Figure 14A, the second section 2 is moved upwards and breaks the breakaway joints 30. Then, the second section 2 can be used to pull the cover sheet out of the first section 1 so that the interior of the cavity 50 is accessible. . Handle 60 remains.
    [0052] The second section 2, when separated from the first section 1, can serve as a handle to open the package. Handle 80 is a three-dimensional structure that can remain attached to the lidding sheet after the joint is broken, and is used to pull the lidding sheet away from the first section to expose the cavity. As noted above, as the cover sheet 40 is secured to the carton so that it cannot be peeled off without exerting force on the carton, it is necessary to separate the gasket 30 to peel off the cover sheet 40. In one embodiment, when the second section 2 is separate from first section 1 (forming handle 80), the rest of the package (first section 1 and optional handle 60) can form/remember the shape of a spoon.
    The handle 80 is produced using materials such as polypropylene, polyethylene, high density polyethylene (HDPE), polyvinyl chloride, polyvinylidene chloride (PVDC), fluorinated-chlorinated resin, fluoropolymer and mixtures thereof. As with other portions of the package, handle 80 is desirably produced from recyclable material. The handle 80 can be produced from the same material as the first section 1 or it can be produced from a different material.
    The handle 80 can be formed having varying thicknesses. In one embodiment, the handle 80 has a thickness different from the thickness of the ferrule surrounding the cavity 50.
    The handle 80 can also provide structural strength to the package. This can be achieved, for example, by strengthening the handle 80 by including one or more ribs in the three-dimensional structure. It is also preferred that the grip 80 is ergonomically designed (i) to be gripped by a thumb and/or finger, and/or (ii) to have a desired texture.
    [0056] Typically, at least a portion of the cover sheet 40 is also affixed to the cover sheet 80. The cover sheet 40 should remain adhered or attached to the grip 80 after separation from the second section 2 and during peeling of the cover sheet 40 of the first section 1. The cover sheet portion is removed from the container by separating the handle 80 from the first section 1.
    [0057] The first section 1 may include a handle 60 that is designed to secure the package after the cover sheet 40 has been removed. Advantageously, handle 60 is designed to be a three-dimensional structure. In one embodiment, handle 60 is formed having varying thicknesses. In another embodiment, in which the container includes a ferrule, the thickness of the handle 60 is greater than the thickness of the ferrule. In yet another embodiment, handle 60 has a thickness that is less than the thickness of the ferrule.
    [0058] The handle 60 can also provide structural strength to the package. This can be achieved, for example, by reinforcing the knob 60 by including one or more ribs. The ribs can beneficially provide rigidity and support to the handle 60. In addition, the ribs can also form or define cavities, which can be used to retain product.
    [0059] Ideally, the handle 60 is ergonomically shaped to be gripped by a thumb and finger.
    [0060] In one embodiment, knob 60 is V-shaped, and in other embodiments, knob 60 may have a rectangular or irregular shape.
    [0061] Optionally, a decoy element can be included. A bait element is a weakened bending line/area (eg, a grooved and/or thinner bending line) of a package that bends up or down or from side to side. It is designed to mislead and/or mislead someone who does not have access to the product in the packaging (eg a child) as to the location of the packaging opening mechanism. The decoy element can be included to provide the packaging with more child safety protection. The ability to flex the lure up and/or down or side to side creates a distraction for a child so that they are less likely to find the proper opening means for the package. Depending on the degree of difficulty of opening desired, more than one bait element (eg bending lines at various angles to each other) can be included in the package.
    [0062] The weakening area of the decoy element can be formed by many means, including mechanical means such as marking or notching the container/packaging, or during molding of the package. In one embodiment, the weakening area of the decoy element is formed as the package is manufactured. Preferably, the bait element is hidden or camouflaged to make it a non-obvious part of the package. Again, although the bait is weakened to allow flexion and movement, it is not so weakened that it breaks or separates.
    [0063] In Figure 15, a bottom view of the package with a decoy element 90 is shown, the decoy 90 being identified along a flex line. As can be seen in this Figure, the first section 1 and the second section 2 are still separated by a breakaway joint 30. In this mode, the opening 95 goes through the breakaway joint 30. In this way, the breakaway joint 30 is split in two. Although not seen in this Figure, a cover sheet 40 is affixed to the top surfaces of the first section 1 and second section 2. In the embodiment shown, the bait 90 extends through the handle 60 of the first section 1 and through the second section 2 In Figure 16, a perspective bottom view of the package with a decoy element 90 is shown. Here again, the decoy 90 extends through the handle 60 of the first section 1 and through the second section 2.
    [0064] Figure 17 is a top view of an individual package, the cover sheet 40 covering the container 3. As can be seen, the cover sheet 40 fully covers the cavity 50 and is at least partially attached to the top surfaces of the first section 1 and second section 2. The cover sheet 40 is secured to the container 3 such that a user cannot hold or secure the cover sheet 40 without first separating the sections 1, 2. A bait 90 allows the package to be flexed in an upward and/or downward direction, as exemplified in Figure 18A and Figure 18B, without breaking or opening the package. As can be seen, when a user attempts to access cavity 50 by flexing along decoy 90, the second section 2 moves up (Figure 18A) or down (Figure 18B) without breaking or separating. Although the modalities shown in the figures show the decoy passing through the first section 1 and the second section 2, it should be understood that the decoy may reside in only one section, for example, in the first section 1 or in the second section 2.
    [0065] The packaging of the invention is designed to have superior strength to protect its contents. For example, cavity 50 has a crush strength of at least about 2 hN (50 lbf). Preferably at least about 4 hN (100 lbf) and more preferably about at least 9 hN (200 lbf).
    [0066] Furthermore, the container 3 and/or the cover sheet 40 of the package can be constructed using materials that provide moisture barrier properties to the package. In one modality, the package is able to maintain a moisture barrier when subjected to a temperature of 40°C, 75% relative humidity, for 3 months.
    [0067] The packaging can also provide protection from UV light. The selection of translucent or opaque materials to form the packaging provides the desired protection for the product. Other desirable characteristics, eg product stability, can affect the selection of material to form the package.
    [0068] The packaging is well suited to protect a medicine, such as a tablet, a liquid, a powder, a capsule or combinations thereof. In one embodiment the drug is a friable tablet.
    [0069] In one embodiment, the tablet is prepared so that the tablet is relatively soft (eg, capable of disintegrating in the mouth or being chewed). The hardness test (crushing hardness) is based on the hardness of the dosage form measured perpendicular to the cross section in the protruding range using a modified Pharmatron Model 6d hardness tester with a 0.5 load cell. Newton (50 g force) (lower forces needed to test the invention). Except where otherwise noted, the test is conducted on two stacked tablets and the hardness is recorded as 50% of the measured hardness. In one embodiment, the tablet hardness is less than about 0.5 hectonewton (5 kilo pounds), such as less than 0.05 hectonewton (0.5 kilo pounds).
    [0070] In another embodiment, the density of the tablet is about at least 0.6 g/cm3. In yet another embodiment, the tablet density is less than about 1.5 g/cm3. In yet another embodiment, the bulk density of the lost coated particles is from about 0.5 g/cm3 to about 1 g/cm3.
    [0071] In one modality, the tablets have a friability of less than 10 percent, such as less than 5 percent, such as less than 3 percent. As used herein, "friability" is measured using USP 24 NF 29, Tablet Friability (section 1216), with the modification to use 3 tablets per 15 revolutions or 3 tablets per 100 revolutions (unless it is noted otherwise) instead of 10 tablets per 100 rotations.
    [0072] One aspect of the present invention is the use of graphic signs or symbols to provide instructions to a user or consumer on how to open the package. Graphic signs can be included on cover sheet 40 and/or container 3. This can be useful for seniors and/or individuals who speak a different language, as the image provides an image with few or no words.
    [0073] In Figure 22, a top view of a package is shown, where the cover sheet 40 has a three-dimensional graphic image 100 (e.g., the block arrow) and text 105. In the embodiment shown, the three-dimensional graphic image 100 is a block arrow that communicates the direction in which the second section 2 must be flexed to open the package. Two graphic images 100 can be used, showing the user to first flex the second section 2 along the joint 30 and then peel off the cover sheet 40 using the resulting handle 80.
    [0074] In this specific modality, the three-dimensional image 100 is placed directly on the opening area of the package. However, it should be understood that the three-dimensional image can be placed anywhere else on the packaging. Alternatively, the image can be formed on the container as the container is molded. Or the graphic image can be embossed or trimmed onto the cover sheet surface to draw the user's attention to the graphic image. Decoy images can be used to distract or mislead users, if desired.
    [0075] To help create the three-dimensional effect of the image, a color or colors can be used. Color shading and highlighting can also help to create the three-dimensional image. The image can be photorealistic. For example, color shadows and highlights can be used to create a photorealistic image that illustrates how the package is opened.
    [0076] In addition, the three-dimensional image can be used to show an area of weakness in the package. Or it can be used to show an area of the package that flexes to open the package. For example, the image can be used to communicate to a user the direction to flex a flap on the package. This can be achieved by including a block arrow that shows the direction in which to flex the first section and/or the second section on the package. In a specific modality, as the package is opened, the three-dimensional image is separated from the package.
    [0077] Figure 23 is a bottom view of a card that has eight containers 3 in a 2 by 4 configuration, with a container 3 being separated from the card. Each container 3 in this embodiment has a first section 1 and second section 2, each separated by a breakaway gasket 30, a cavity 30, a handle 50, a handle 80 and a lure 90. Although not seen in Figure 23, a sheet cover 40 is disposed on the top surface of each container 3. During molding, a graphic image 100 and text 105 may be molded onto the package, providing instructions to a user. Each container 3 is secured to adjacent containers 3 in a detachable manner, so that a user can easily separate one container 3 from another 3, without breaking the joint 30 or peeling off the cover sheet 40.
    [0078] Figure 24 is a top view of the sheet of Figure 23, which has eight individual containers, with one container 3 having been separated from the sheet. Each container 3 includes a cover sheet 40, which covers the first and second sections (1, 2), the gasket 30, a cavity 50, a handle 60, a handle 80 and a lure 90.
    [0079] The packaging is well suited to protect a medicine, such as a tablet, a liquid, a powder, a capsule or combinations thereof. In one embodiment the drug is a friable tablet.
    [0080] In one embodiment, the packaging is used to dispense a unit dose of a drug. Drug dosing benefits from packaging design by enclosing an individual dose in the packaging. User compliance is enhanced by instructions printed on the individual package for each dose.
    [0081] If used, the card is configured with at least 2 packages. More preferably, the card has at least 6 packages. Even more preferably, the card has at least 8 packages. The carton provides another degree of safety for children by adding an additional step, which requires separating an individual carton from the other cartons on the carton.
    [0082] The package or cartouche can be manufactured using a variety of means. For example, the package can be produced by a molding process such as injection molding, bi-injection molding, compression molding, thermoforming molding, casting molding or any other molding process. Furthermore, the package can be formed using three-dimensional printing methods. Ideally, the package is produced by injection molding, where a container is formed from a semi-plastic material.
    [0083] After the container is formed, a product is placed in the cavity. Then, the cover sheet can be placed over at least a portion of the container to cover the cavity and seal the product within the cavity and container. The cover sheet desirably covers at least a portion of the first section 1 and second section 2. The container and the cover sheet can be joined by any sealing method known in the art that properly seals a product within the cavity. For example, if the product has a low stability or service life so that an airtight seal is required, then the container materials and cover sheet and sealing method are selected to achieve an airtight seal to the air. around the cavity. Sealing methods that can be used, for example, include thermobonding, adhesive seals (such as with thermally activated adhesive or solvent), RF or sonic seals, or any other suitable means. The container and cover sheet materials can be pretreated to facilitate sealing of such materials together. For example, a coating can be applied to the container and/or the cover sheet to allow thermosetting.
    [0084] The tear gasket and optional bait can be formed to have the desired strength during molding or alternatively the tear gasket and optional bait can be marked or notched after the container is formed. The joint weakening and optional bait can be formed at any desired stage of package formation. For example, the package can be passed through equipment designed to form the desired type of weakening once the cavity has been filled, and the container and cover sheet are sealed together. Once the package or carton has been formed with its desired child-safety features, it can be passed through die-cut equipment for separation.
    [0085] The cartouche can be produced using the same materials described for the packaging.
    [0086] Alternatively, the present invention may include a package comprising a first section and a second section connected at a breakaway joint, the first section or second section being adapted to pivot at a fulcrum between the first section and the second section to assist in breaking the breakaway joint so as to separate at least a portion of the first section from at least a portion of the second section so that, upon rupture, the package is opened or allows access to an opening feature, the breakaway joint may flex/move before it breaks.
    [0087] In another alternative embodiment, the present invention is a packaging comprising a plastic container that has a first section and a second section connected to a breakaway joint, the first section comprising a cavity, a handle and a sheet of cover, wherein the cover sheet is adhered to at least a portion of the first section and the cover sheet covers the cavity; the first section or the second section being adapted to pivot at a fulcrum between the cover sheet and the gasket to assist in breaking the breakaway joint so as to separate the first section and the second section, such that upon rupture, the the remainder of the package is shaped like a spoon.
    [0088] As should be understood from the foregoing, a package formed in accordance with the principles of the present invention is simple in construction, can be produced economically and relatively simply, provides a protective environment for the products and can be opened immediately without the use of accessories such as scissors or knives, but cannot be opened immediately by children. Example 1
    [0089] A package is manufactured according to the invention, whereby a drug is placed inside the cavity of the package. The package includes three-dimensional graphic images to show how to open the package. The package does not include a decoy. A study using the package is carried out, where children and adults receive the package and are asked to open the package. The study found that at least about 80% of children aged 3.5 to 4 years old cannot open the package and more than about 90% of adults aged 65 to 70 are able to open the package. Example 2 Packaging tensile test
    [0090] Testing was performed to characterize the force required to remove the second tearable/removable section (eg flap) from the first section. The test does not employ section two movement, so the fulcrum was used. Instead, section two was pulled perpendicular to the bend line at 180 degrees. The test was performed on a Chatillon LR5K traction/compression tester with a traction speed of 1.27 centimeters/minute (0.500 inch/minute), using the procedure detailed below. Procedure: 1. Scissors are used to cut along the perforations to separate the packaging units in a multi-pack into individual units. 2. Scissors are used to remove the cavity that contains the product from the remaining portion of the package that contains the opening feature.
    [0091] Note: This step has been performed so that the grips can sufficiently grip the test sample without the cavity being an obstruction. 3. A knife (eg Exacto, utility) is used to cut the cover material that is situated behind the opening feature. Care is taken to avoid destroying the packaging.
    [0092] Note: This step is performed for the following reasons: - The samples being tested were sealed with a cover material so that they are representative of a finished package. - The cover material is being cut so that the tensile strength limit of the cover material is not part of the test. 4. The space between the bottom of the upper jaw and the top of the lower jaw is adjusted to be approximately 1.111 centimeter (7/16" (0.4375" inch)). 5. The second removable section (hereafter referred to as the tab) is located on the upper grip. The cover side of the package is located on the movable side of the claw. 6. The remaining part of the packaging is located in the lower grip.
    [0093] Note: The sample is positioned as follows. 7. The open feature is placed parallel to the top of the lower jaw and the bottom of the upper jaw. 8. Open feature is placed centered within the upper and lower grips; that is, there is equal space on either side of the open feature, the left and right outer edges of the upper and lower grippers. 9. The jaws are tight enough so that the specimen does not slip during testing. 10. The load cell is adjusted to a sufficient capacity so that the force required to separate the flap from the first section can be quantified.
    [0094] Notes: A 500 Newton load cell was used.
    [0095] The test speed was set to 1.27 centimeters per minute (0.500 inches per minute).
    [0096] The offset is set to a distance that is sufficient to capture the peak force.
    [0097] The offset was set at 0.381 centimeter (0.1500 inch).
    [0098] The test was set in a pull mode so that the upper and lower grips moved in the opposite direction to each other. 11. Once the sample is loaded, the load is zeroed. 12. The test runs.
    [0099] Note: The upper and lower jaws move away from each other so that the force required to separate the second section from the first section is quantified. 13. After the test is complete, the test sample is removed and the upper and lower jaws are repositioned to their original positions. 14. The process is repeated as needed until all intended samples are tested.
    [00100] The average force required to separate section two from section one was determined to be 58.76 N (13.21 lbf). Example 3 Packaging Reservoir/Cavity Compression Test
    [00101] The compression test of the reservoir/cavity of the package against the compressive strength of the reservoir/cavity of thermoformed cavities was performed. Procedure: 1. Scissors are used to cut along the perforations to separate the packaging units in a multi-pack into individual units. 2. A bottom accessory such as a rigid stationary platform is used. 3. A cylinder is used as a top accessory with a diameter large enough to cover the area of the package containing the product. 4. The space between the top and bottom fitting is adjusted to accommodate the height of the test pack without compressing the test pack or having an unnecessary gap (ie, the test pack can be modified with just enough space not to drag in the top accessory). 5. A load cell with sufficient capacity, such that the force required to compress the cavity to 50% of its original height can be quantified, is used.
    [00102] Note: A 500 Newton load cell was used for sample packages 1 to 5.
    [00103] A 5 KiloNewton load cell was used for sample pack 6 (the injection molded pack).
    [00104] The test speed has been set to 1.27 centimeters per minute (0.500 inches per minute).
    [00105] The offset has been set to a minimum distance of 50 percent of the height of the original package.
    [00106] The heights of the package were determined by observing the approved package design or by taking measurements. 6. The test was set to Compression mode so that the upper attachment moved towards the lower attachment. 7. Once the sample was centered under the top fixture, the load was zeroed. 8. The test runs.
    [00107] Note: The top and bottom fittings move towards each other so that the force required to compress the sump/cavity to a minimum of 50% of its original height is quantified. 9. After the test is completed, the tested specimen is removed and the upper and lower jaws are repositioned in their original positions. 10. The process is repeated as needed until all intended samples are tested.
    [00108] The following table summarizes the forces necessary to compress the thermoformed cavities and the injection molded polypropylene (PP) packaging of the invention. As noted in the procedure above, the reservoirs/cavities were compressed to 50% of their original height. This level of compression was used as product damage was likely (to some degree) to occur at that point. The reservoirs/wells tested were all sealed with a cover sheet (sheet cover material) and the wells were all empty. The test was performed on a Chatillon LR5K traction/compression tester with a traction speed of 1.27 centimeters/minute (0.500 inch/minute). Table 1 below shows the results of such a test. Table 1
    Example 4
    [00109] Table 2 below summarizes the Water Vapor Transmission Rate (WVTR) data that characterizes the barrier properties of injection molded polypropylene (PP) packaging. The packages were sealed with a cover sheet made of metal cover sheet material. The individual cavities were tested using the Mocon Permatran-W 3/33 test equipment and methodology. Procedure
    [00110] 1. Representative samples of a form of final packaging have been identified; i.e., reservoirs/cavities formed and sealed to a cover sheet material.
    [00111] Note: (1) The cover sheet material was consistent with standard cover material available in the industry.
    [00112] (2) The sealing process for adhering the foil coating to the formed material was consistent with standard sealing processes available in the industry (eg gasket plate). 2. Distilled water was aspirated through a hypodermic needle. 3. The hypodermic needle was inserted through the cover material so that 0.1 ml of water could be injected into the reservoir/cavity containing the packaging product. 4. The hypodermic needle was removed from the package, taking care that the cover material was dry and the remaining hole was sealed with a fast curing epoxy. 5. The samples were allowed enough time for the fast curing epoxy to dry. 6. Once dry, the samples were loaded into the packaging test cells and affixed to the Mocon Permatran-W 3/33 test equipment. 7. The test cells from the package were attached to the instrument via the U-pin of the Permatran-W 3/33. 8. The proper calibration has been loaded.
    [00113] Note: Proper calibration is one for a high barrier package having a low permeation rate. 9. The test duration was set to a duration suitable for the calibration being used.
    [00114] Note: A two hour interval was selected based on the calibration being used. 10. The convergence period was set at 4.
    [00115] Note: "Convergence Period" is a setting within the software to define test completion. This refers to packaging at a steady state permeation rate. 11. Testing was initiated and continued until the Convergence Criterion was met. 12. Data has been printed. 13. The U-pin was loosened and repositioned so that the test cells from the pack could be removed and the test packs could be removed. 14. The process of loading new test samples into the packaging test cells, attaching to the Mocon Permatran-W 3/33 and starting the test was repeated until all test samples were tested.

    [00116] Although the invention has been described above with reference to specific embodiments and illustrated in the drawings of its specific embodiments, it will be evident that many changes, modifications and variations can be made without departing from the concept of the invention disclosed herein. Consequently, it is intended to cover all such changes, modifications and variations in the spirit and broad scope of the appended claims. All patent applications, patents, and other publications cited in the present invention are hereby incorporated by reference in their entirety.
    权利要求:
    Claims (20)
    [0001]
    1. A package comprising: a container having a first section and a second section connected to a breakaway gasket (30) wherein the first section comprises a cavity; and a cover sheet (40), wherein the cover sheet is adhered to at least a portion of the first section and at least a portion of the second section, and the cover sheet covers the cavity; the first section or second section being adapted to pivot to help break the breakaway joint to separate the first section and second section, characterized in that the first section or second section is adapted to pivot at a fulcrum ( 10) between the cover sheet and the gasket to help break the breakaway gasket to separate the first section and second section, such that at break, the first section and second section are still adhered to the cover sheet, and the second section serving as a handle (80) for removing the sheet from the first section to expose the cavity.
    [0002]
    2. Packaging according to claim 1, characterized in that a portion of the first section extends beyond the plane of the breakaway joint (30), so as to be partially surrounded by the second section.
    [0003]
    3. Packaging according to claim 1, characterized in that a portion of the second section extends beyond the plane of the breakaway joint (30) so as to at least partially surround the first section.
    [0004]
    4. Packaging according to any one of claims 1 to 3, characterized in that the container is an injection molded container.
    [0005]
    5. Packaging according to any one of claims 1 to 4, characterized in that the container is made of a plastic material selected from the group consisting of polypropylene, polyethylene, high density polyethylene (HDPE), polyvinyl chloride, polyvinylidene chloride (PVDC), fluorinated-chlorinated resin, fluoropolymer and mixtures thereof.
    [0006]
    6. Packaging according to any one of claims 1 to 5, characterized in that it further comprises a lure (90) that is adapted to flex.
    [0007]
    7. Packaging according to claim 1, characterized in that the cover sheet (40) includes a three-dimensional graphic image (100) that shows how to break the joint.
    [0008]
    8. Packaging, according to claim 1, characterized by the fact that at least about 80% of children aged 3.5 to 4 years old cannot open the packaging, and more than about 90% of adults with age 65 to 70 can open the package.
    [0009]
    9. Packaging according to any one of claims 1 to 8, characterized in that the first section or the second section comprises an opening that exposes a bottom surface of the cover sheet.
    [0010]
    10. Packaging according to any one of claims 1 to 9, characterized in that the cavity (50) has a crush strength of at least 2 hN (50 lbf).
    [0011]
    11. Packaging according to any one of claims 1 to 10, characterized in that most of the side wall (52) of the cavity is at an angle of about 0° to about 20°, as measured by a plane perpendicular to the cover sheet.
    [0012]
    12. Packaging according to any one of claims 1 to 11, characterized in that the cavity has a side wall and a bottom, and the bottom (54) of the cavity (50) has a thickness that is greater than the thickness of the sidewall (52).
    [0013]
    13. Packaging according to any one of claims 1 to 11, characterized in that the cavity has a side wall, and the thickness of the bottom (54) of the cavity (50) is greater than 80% of the thickness of the side wall (52).
    [0014]
    14. Packaging according to any one of claims 1 to 13, characterized in that a lever ratio, defined by the distance from the fulcrum (10) to a distal point of the breakable joint (30) compared to the length of a lever defined by the first section or the second section is at least about 1:1.
    [0015]
    15. Packaging according to any one of claims 1 to 14, characterized in that the breakaway joint (30) breaks as the second section is moved in a rotational direction for the first section, or the first section is moved in a rotational direction for the second section.
    [0016]
    16. Packaging according to any one of claims 1 to 15, characterized in that the first section additionally comprises a handle portion (60) to hold the at least one cavity.
    [0017]
    17. Packaging according to any one of claims 1 to 16, characterized in that the cavity holds a drug.
    [0018]
    18. Pack characterized by the fact that it comprises at least one package as defined in claim 1.
    [0019]
    19. Cartridge according to claim 18, characterized in that it is formed by injection molding.
    [0020]
    20. Cartridge according to claim 19, characterized in that it is made of a plastic material selected from the group consisting of polypropylene, polyethylene, high density polyethylene (HDPE), polyvinyl chloride, polyvinylidene chloride (PVDC) , fluorinated-chlorinated resin, fluoropolymer and mixtures thereof.
    类似技术:
    公开号 | 公开日 | 专利标题
    BR112015029098B1|2021-05-18|packaging and card
    US7607834B2|2009-10-27|Peelable pouch containing a single or multiple dosage forms and process of making same
    US20070205127A1|2007-09-06|Peelable pouch containing a single film dosage and process of making same
    ES2590984T3|2016-11-24|Safety blister pack for children
    JP4196385B2|2008-12-17|Container for taking out
    JP2013544714A|2013-12-19|Dispensing container
    AU2007202473A1|2008-01-03|Blister package
    JP6046877B2|2016-12-21|Guided tear method for pouch laminates to enable product removal
    NZ554122A|2009-11-27|Peelable child-resistant packaging for wafer pharmaceutical forms
    US20130081968A1|2013-04-04|Film container of a blister that cannot be extruded
    JP2006273395A|2006-10-12|Packaging film
    US10017303B2|2018-07-10|Child resistant medical package
    JP2003237836A|2003-08-27|Case of press-through pack package
    EP3105142B1|2018-01-31|A package comprising means for opening blisters
    WO2007106338A2|2007-09-20|Improved peelable pouch containing a single film dosage and process of making same
    US20210198003A1|2021-07-01|An improved container
    JP2000281130A|2000-10-10|Blister packaging member, bottom member and resin sheet
    JP3222422B2|2001-10-29|Package
    JPH0626872U|1994-04-12|Portable packaging
    AU2019336271A1|2021-05-06|An improved container
    JPH10167320A|1998-06-23|Ptp package easy to unseal
    JP2001039469A|2001-02-13|Package
    同族专利:
    公开号 | 公开日
    CA2912999A1|2014-11-27|
    AU2014268724A1|2015-11-26|
    HK1221447A1|2017-06-02|
    EP2999643B1|2017-10-25|
    KR102218150B1|2021-02-23|
    RU2015154483A3|2018-03-28|
    US20140346081A1|2014-11-27|
    RU2652493C2|2018-04-26|
    CN105358448B|2018-06-22|
    US10159625B2|2018-12-25|
    CA2912999C|2021-03-16|
    BR112015029098A2|2017-07-25|
    HK1222379A1|2017-06-30|
    WO2014189971A1|2014-11-27|
    CN105358448A|2016-02-24|
    RU2015154483A|2017-06-26|
    EP2999643A1|2016-03-30|
    KR20160012174A|2016-02-02|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US3689458A|1970-03-23|1972-09-05|Hellstrom Harold R|Quick-opening fulcrum package|
    US3630346A|1970-06-01|1971-12-28|Lilly Co Eli|Components for making a strip package|
    US3835995A|1972-07-12|1974-09-17|Paco Packaging|Tamperproof package|
    US3809220A|1972-07-24|1974-05-07|Becton Dickinson Co|Child safety package|
    US3921805A|1972-10-10|1975-11-25|Newton L Compere|Rupturable blister pill package with safety backing|
    US3872970A|1974-01-11|1975-03-25|Lilly Co Eli|Child-resistant blister package|
    US4371080A|1981-02-20|1983-02-01|Paco Packaging Incorporated|Childproof package for multiple products|
    CH677473A5|1988-12-02|1991-05-31|Alusuisse|Container with resealable cover - has edge with weakened zones forming cone parting surface widening towards top|
    DE9313193U1|1993-07-26|1993-10-28|Klocke Verpackungs Service|Packaging for lumpy goods|
    US5529188A|1994-09-28|1996-06-25|Becton Dickinson And Company|Child resistant carded type blister folder|
    US5511665A|1994-10-31|1996-04-30|G. D. Searle & Co.|Child-resistant package|
    US5775505A|1996-02-27|1998-07-07|Vasquez; William M.|Blister card package|
    DE19706825A1|1997-02-21|1998-09-03|Lohmann Therapie Syst Lts|Peelable sealed edge bag in child-proof design, process for its production and its use|
    DK1015352T3|1997-04-01|2008-01-14|Cima Labs Inc|Blister and packaged tablets|
    FR2761962B1|1997-04-14|1999-06-04|Oreal|THERMOPLASTIC TRAY FOR THE EXTEMPORANEOUS MIXTURE OF AT LEAST TWO PRODUCTS|
    US6036016A|1998-04-20|2000-03-14|Pinnacle Intellectual Property Services, Inc.|Blister package with easy tear blister|
    US6422391B1|1999-12-20|2002-07-23|L. Perrigo Company|Child-resistant medicament package and method of opening|
    SE0101433L|2001-04-25|2002-01-22|Ragnar Winberg|Blister|
    AU2003268909A1|2002-10-04|2004-04-23|Elan Pharma International Limited|Improved blister packaging|
    DE102004047447B4|2004-09-30|2008-01-03|Lts Lohmann Therapie-Systeme Ag|Peelable, child resistant packaging for flat flexible objects, use of these packages and methods of packaging flat, flexible objects|
    EP1836102B1|2005-01-14|2011-11-30|Cima Labs Inc.|Bend and peel tablet package|
    CA2643469A1|2006-02-23|2007-09-07|Meadwestvaco Corporation|Improved child resistant package|US9475709B2|2010-08-25|2016-10-25|Lockheed Martin Corporation|Perforated graphene deionization or desalination|
    US10653824B2|2012-05-25|2020-05-19|Lockheed Martin Corporation|Two-dimensional materials and uses thereof|
    TW201504140A|2013-03-12|2015-02-01|Lockheed Corp|Method for forming perforated graphene with uniform aperture size|
    US9572918B2|2013-06-21|2017-02-21|Lockheed Martin Corporation|Graphene-based filter for isolating a substance from blood|
    US9988194B2|2013-07-10|2018-06-05|Amcor Flexibles|Gas and light proof, double-shell blister packs for medicinal contents|
    US9248611B2|2013-10-07|2016-02-02|David A. Divine|3-D printed packaging|
    US9744617B2|2014-01-31|2017-08-29|Lockheed Martin Corporation|Methods for perforating multi-layer graphene through ion bombardment|
    CN105940479A|2014-01-31|2016-09-14|洛克希德马丁公司|Methods for perforating two-dimensional materials using a broad ion field|
    EP3099645A4|2014-01-31|2017-09-27|Lockheed Martin Corporation|Processes for forming composite structures with a two-dimensional material using a porous, non-sacrificial supporting layer|
    US9834809B2|2014-02-28|2017-12-05|Lockheed Martin Corporation|Syringe for obtaining nano-sized materials for selective assays and related methods of use|
    US9610546B2|2014-03-12|2017-04-04|Lockheed Martin Corporation|Separation membranes formed from perforated graphene and methods for use thereof|
    EP3116625A4|2014-03-12|2017-12-20|Lockheed Martin Corporation|Separation membranes formed from perforated graphene|
    SG11201701654UA|2014-09-02|2017-04-27|Lockheed Corp|Hemodialysis and hemofiltration membranes based upon a two-dimensional membrane material and methods employing same|
    CA2994549A1|2015-08-05|2017-02-09|Lockheed Martin Corporation|Perforatable sheets of graphene-based material|
    JP2018530499A|2015-08-06|2018-10-18|ロッキード・マーチン・コーポレーション|Nanoparticle modification and perforation of graphene|
    DE102016102084A1|2016-02-05|2017-08-10|B. Braun Avitum Ag|Filter module Packing unit|
    JP2019517909A|2016-04-14|2019-06-27|ロッキード・マーチン・コーポレーション|Two-dimensional membrane structure having a flow path|
    WO2017180141A1|2016-04-14|2017-10-19|Lockheed Martin Corporation|Selective interfacial mitigation of graphene defects|
    JP2019519756A|2016-04-14|2019-07-11|ロッキード・マーチン・コーポレーション|In-situ monitoring and control of defect formation or defect repair|
    WO2017180135A1|2016-04-14|2017-10-19|Lockheed Martin Corporation|Membranes with tunable selectivity|
    US10980919B2|2016-04-14|2021-04-20|Lockheed Martin Corporation|Methods for in vivo and in vitro use of graphene and other two-dimensional materials|
    CA3020686A1|2016-04-14|2017-10-19|Lockheed Martin Corporation|Method for treating graphene sheets for large-scale transfer using free-float method|
    EP3728068B1|2017-12-22|2022-02-02|Cryovac, LLC|Package, process and apparatus for making said package|
    法律状态:
    2018-11-06| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2019-12-31| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2021-04-06| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    2021-05-18| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/05/2014, OBSERVADAS AS CONDICOES LEGAIS. |
    优先权:
    申请号 | 申请日 | 专利标题
    US201361825660P| true| 2013-05-21|2013-05-21|
    US201361825669P| true| 2013-05-21|2013-05-21|
    US201361825740P| true| 2013-05-21|2013-05-21|
    US201361825691P| true| 2013-05-21|2013-05-21|
    US201361825704P| true| 2013-05-21|2013-05-21|
    US201361825652P| true| 2013-05-21|2013-05-21|
    US61/825,704|2013-05-21|
    US61/825,669|2013-05-21|
    US61/825,652|2013-05-21|
    US61/825,660|2013-05-21|
    US61/825,691|2013-05-21|
    PCT/US2014/038842|WO2014189971A1|2013-05-21|2014-05-20|Child-resistant package|
    [返回顶部]