• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Medical device for narrowing or shutting off a body channel, comprising a band part (1) which can be laid around the body tissue (2) surrounding the body channel and can be closed to form a ring enclosing a passage opening (6) for the body tissue, the band part (1) a hollow chamber (3) and wherein by introducing a fluid into the hollow chamber (3), the passage opening (6) is reduced in size, and a pump unit (10) for conveying the fluid, which can be controlled by an electronic control of the device electrical drive (15 ), wherein the pressure of the fluid in the hollow chamber (3) corresponding to or dependent on the pressure of the electronic control is detected, wherein the device comprises an air pressure sensor (23) for detecting the atmospheric pressure, and by means of the electronic control of the pressure of Fluids in the hollow chamber (3) in response to a stored reference value of Druckwe rts and is adjustable by a stored reference value of the air pressure value.
    公开号:AT518714A1
    申请号:T274/2016
    申请日:2016-06-03
    公开日:2017-12-15
    发明作者:
    申请人:Ami Agency Medical Innovations Gmbh；
    IPC主号:
    专利说明:

    The invention relates to a medical device for narrowing or shutting off a body passage, comprising a band member which is laid around the body tissue surrounding the body passage and can be closed to a passage opening for the body tissue surrounding ring, wherein the band member has a hollow chamber and wherein Introducing a fluid into the hollow chamber, the passage opening can be made smaller, and a pump unit for conveying the fluid, which has an electric drive controllable by an electronic control of the device, wherein the electronic control of the pressure of the fluid in the hollow chamber or depending on this dependent Pressure value can be detected.
    Medical facilities for narrowing or shutting off a body passage are u. a. used as artificial (closing) muscles to support or replace weakened natural muscles in the human or animal body. Examples of applications of such devices are anal tapes for occluding an optionally artificial, anus and artificial sphincter for treating incontinence to occlude the urethra (Har urethra). Further fields of use are e.g. Gastric bands for narrowing the gastrointestinal tract or ligaments for closing a bile duct. Such medical devices are also referred to as cuffs, cuffs or artificial sphincters.
    If required, the hollow chamber can be emptied by the user in order to increase the cross-sectional area of the passage opening and to allow substances and / or liquids contained in the body passage to pass. For example, when used as an artificial sphincter for the urethra is often followed by a subsequent automatic closure of the body passage by pumping back fluid (possibly, via a throttle valve) in the hollow chamber of the device. A pump for pumping fluid is usually implanted in the scrotum in such an artificial male urinary sphincter. The pumping of fluid from the hollow chamber can then be done by pressure on a flexible part of the pump. The pumping back of fluid in the hollow chamber can be done by a resilient element of the pump. The passage opening of the medical device can often also be reduced again by a conscious action of the user, that is to say by manual actuation of the pump. For example, US Pat. No. 5,478,305 A discloses a medical device which is referred to in this document as a cuff and can be used to treat urinary or fecal incontinence. The cuff is made of silicone. By filling the cuff with fluid, the pressure in the cavity of the cuff rises and closes the body passageway. Examples of gastric bands can be found in EP 1 389 453 B1.
    Also known implantable medical devices through which a liquid drug can be dosed to a desired location within the body. From US 5,976,109 A such a device is known, in which a container with a flexible wall, for example in the form of a bellows, is provided, wherein a cover part of the container for metering the medicament is adjusted by an electric drive. The container thus simultaneously forms a reservoir for the drug and a portion of a pump through which the drug is delivered to the desired location in the body.
    A device of the type mentioned is apparent from DE 100 13 519 A1. It is an implantable sphincter prosthesis for use in urinary incontinence. To promote the fluid is an electrically driven pumping part. For energy supply here an extracorporeal supply and control device is provided, from which the drive of the pumping part can be supplied with electrical energy wirelessly. In the area of the band part is a
    Pressure sensor provided by the pressure acting on the urethra by the band part is determined. This pressure sensor can be used for calibrating the system, ie for adjusting the closing pressure. A use for controlling the drive is mentioned.
    The object of the invention is to provide a device of the type mentioned, which allows improved operation. According to the invention, this is achieved by a device having the features of claim 1.
    The device according to the invention has an air pressure sensor. From the electronic control thus issued by this air pressure sensor air pressure value is detected, which corresponds to the atmospheric pressure. In particular, the controller may determine a change in the volume of fluid in the system, and optionally the controller, using pressure readings corresponding to or depending on the respective pressure of the fluid in the hollow chamber and sensed air pressure values corresponding to the respective atmospheric pressure adjusted pressure for the fluid thereto and / or in the event of exceeding an upper or lower limit for the detected volume of liquid issued a warning.
    Such a change in the volume of liquid can be caused for example by osmosis or by a leak.
    By means of the device according to the invention, it is advantageously possible to achieve optimum pressure conditions at the urethra.
    A pressure value corresponding to the pressure of the fluid in the hollow chamber can be detected in a possible embodiment by means of a pressure sensor arranged in the fluid.
    An arrangement of a pressure sensor on a passage opening limiting surface of the hinge part is conceivable and possible. In any case, a pressure value detected by such a pressure sensor depends on the pressure of the fluid in the hollow chamber and may preferably be at least substantially proportional to the pressure of the fluid in the hollow chamber.
    A pressure value could also be measured by means of a strain gauge glued to a membrane which deforms due to pressure fluctuations. The membrane defines a space in which the fluid is located. For example, the membrane could also be formed by a portion of the band member itself. It is formed by such a membrane with a glued strain gauge, a pressure sensor adjacent to the fluid. In any case, a pressure value detected by a pressure sensor formed in this way also depends on the pressure of the fluid in the hollow chamber and may preferably be at least substantially proportional to the pressure of the fluid in the hollow chamber.
    Depending on the electric drive used, a pressure value corresponding to or dependent on the pressure of the fluid in the hollow chamber could also be derived from the current consumption of the electric drive of the pump device.
    An advantageous embodiment provides that the pump unit has a pump part which has a receiving space filled with the fluid, the volume of which can be changed by means of the drive. For example, the pumping part may be one of a bellows closed by a bottom part and a cover part. A design of the pumping part in the form of a piston-cylinder unit is conceivable and possible. The pressure sensor for detecting the pressure of the fluid in the hollow chamber of the band part can be arranged in such a receiving space of a pump part. An arrangement directly in the hollow chamber of the band part or in the channel of the band part with the pump part connecting hose is conceivable and possible.
    Preferably, the device comprises a locally separate from the pump unit (and the band part) operating unit, which has at least one user-operable control element to open the body passage and / or shut off. The operating unit advantageously has an operating electronics unit which communicates with a pump electronics unit of the pump unit via a radio link. This operating unit may be provided outside the body. An implantation of the operating unit, regardless of the location of implantation of the band part and the pump unit, is conceivable and possible.
    The air pressure sensor can be arranged in the (implanted or arranged outside the body) operating unit. An arrangement of the air pressure sensor in the pump unit is possible.
    The device can be designed, for example, as an artificial urethra sphincter. In other embodiments, the device according to the invention may e.g. be designed as an artificial anal sphincter, artificial "sphincter of oddi" or artificial closure of a duct for bile.
    Shutting off the body canal can be complete or partial (= narrowing).
    Further advantages and details of the invention are explained below with reference to the accompanying drawings. In this show:
    1 shows a schematic representation of a device designed as an artificial urethra sphincter, in a release state of the strap part in which the ureter is opened;
    FIG. 2 shows a representation analogous to FIG. 1 in a shut-off state of the band part in which the ureter is closed; FIG.
    3 and 4 are oblique views of the free, that is not implanted, band portion of the device in an open and closed state, in accordance with the release state.
    Fig. 5 is a longitudinal center section (parallel to the longitudinal center axis of the passage opening and passing through this) by the band member in the state of Fig. 4 and
    Fig. 6 is a longitudinal center section analogous to FIG. 5, but in the shut-off state of the band part.
    An embodiment of a device according to the invention is shown in the figures.
    A band part 1 of the device is annular around the bodily tissue surrounding the body 2, here the urethra, laid. The band part 1 has a hollow chamber 3 which extends in the direction of the longitudinal extent of the band part, in the exemplary embodiment substantially over the entire length of the band part. The band part 1 is thus formed like a hose with ends closed on both sides.
    At the two ends of the hinge part 1, a first and a second closure part 4, 5 are arranged. The first closure part 4 has an insertion opening 4a into which a tongue 5a of the second closure part 5 can be inserted and latched therein.
    The closure parts 4, 5 thus form a closure with which the band part 1 can be closed to form a ring, in particular a circular ring, cf. In the closed state, the band part 1 surrounds a passage opening 6 for the body tissue 2 surrounding the body passage.
    In the hollow chamber 3 is a fluid, in particular a liquid. The size of the passage opening 6 depends on the amount of fluid in the hollow chamber 3. By introducing fluid into the hollow chamber 3, the passage opening 6 can be reduced. Here, an inner, i. the longitudinal central axis 7 of the passage opening 6 adjacent, flexible portion 1 a of the band member 1 is displaced in the direction of the longitudinal central axis 7, as is known. By discharging fluid from the hollow chamber 3, the passage opening 6 can be increased again.
    Fig. 5 shows the state in which the passage opening 6 is the largest (wherein the pressure of the fluid in the hollow chamber 3 corresponds to the ambient pressure), Fig. 6 shows a state filled with more fluid, in particular the maximum filled with fluid state (FIG the pressure of the fluid in the hollow chamber 3 is above the ambient pressure). In Fig. 6 are wrinkles, as they would arise in particular, if the band part is not placed around the ureter, not shown.
    A remote from the longitudinal center axis 7 back portion 1b of the band member 1 may be formed stiffer, in contrast, in particular by means of a reinforcing layer, whereby a deformation of the back portion can be at least largely avoided.
    In the closed state of the band part 1, this can therefore assume a release state in which the body channel is opened (see Fig. 1), and a shut-off state in which the body channel is closed (see Fig. 2). In the release state, the pressure of the fluid in the hollow chamber 3, for example, the ambient pressure (= atmospheric pressure) correspond.
    In other embodiments of the invention, the body passage could also be narrowed to different degrees without being completely closed. The band part would then assume different constrictions.
    Different modifications of the design of the strap part are conceivable and possible, it would be possible, for example, to omit special closure parts attached to the strap part 1 altogether and to sewn the two ends of the strap part together.
    The band member 1 may be made of silicone in a known manner. Other biocompatible materials are basically used.
    The band member 1 is connected via a hose 9 with a locally separated from the band part 1 pumping part 11 of a pump unit 10 in conjunction, see. 1 and 2. By means of the pump unit 10, the amount of fluid in the hollow chamber 3 of the
    Band Part 1 to be changed.
    In the exemplary embodiment, a connecting piece 8 is integrally formed on one of the closure parts, the interior of which is in communication with the hollow chamber 3 via a channel running through the closure part. Such a connection piece could also be provided at a different location of the hinge part. The hose 9 is connected to the connecting piece 8.
    The pumping part 11 of the pumping unit 10 has a receiving space 12 filled with fluid. In the exemplary embodiment, the pumping part 11 is formed by a bellows, which is closed by a bottom part 13 and a cover part, which constitutes an adjusting element 14. An electric drive 15 acts on the adjusting element 14 via a gear 16, for example a worm gear, in order to change the volume of the receiving space 12. The gear 16 is favorably self-locking, so that a once set position of the actuating element 14 is held without supply of electrical energy to the drive 15.
    Thus, in the exemplary embodiment, the pump part 11 simultaneously forms a reservoir for the fluid, with which the hollow chamber 3 of the band part 1 is filled to close the body channel.
    The pump part 11 could for example also be formed by a piston-cylinder unit, wherein the actuating element 14 would be formed by the piston of this piston-cylinder unit.
    The pump unit 10 furthermore has an electric drive 15 for the pump part 11. The electric drive 15 is actuated by a pump electronics unit 17 of the pump unit 10. The pump electronics unit 17 is supplied from a battery 18 of the pump unit 10 with electrical energy, as well as the drive 15. The battery 18 may in particular be a rechargeable battery (= accumulator). The charging could be done without contact by a arranged outside the body inductively coupled charger.
    The components of the pumping unit 10 are arranged in a housing 26. The housing 26 is made of a biocompatible material or is enveloped by such.
    For adjusting the band part 1 between the shut-off state and the release state is a locally separate from the pump unit 10 arranged operating unit 19, which has at least one user-operable control element 21, such as a button. Other controls can be provided. An operating electronics unit 20 of the operating unit 19 in this case communicates with the pump electronics unit 17 via a radio link.
    The pump electronics unit 17 and the operating electronics unit 20 together form the electrical control of the medical device of the invention.
    The operating unit 19 can be arranged outside the body. An implantation of the operating unit 19 is conceivable and possible.
    To supply the control unit 19 with electrical energy is used (not shown in the figures) battery.
    A separate control unit could in principle also be omitted, wherein at least one user-operable control element would be arranged on the pump unit. This would have to be actuated accordingly from outside the body.
    With the pump electronics unit 17, a pressure sensor 22 is connected, which is in the embodiment shown in the fluid-filled receiving space 12 of the pumping part 11. By means of the pressure sensor 22 is thus detected by the electronic controller 17, the pressure of the fluid in the receiving space 12, which corresponds to the pressure of the fluid in the hollow chamber 3.
    In addition, an air pressure sensor 23 is connected to the pump electronics unit 17. By means of this can be detected by the electronic controller 17, the ambient pressure corresponding to the atmospheric pressure. The air pressure sensor 23 could also be arranged in the operating unit 19 and the value detected by it could be transmitted via the radio link to the pump electronics unit 17. The evaluation of a pressure value detected by means of the pressure sensor 22 and an air pressure value detected by means of the air pressure sensor 23 thus takes place in the pump electronics unit 17 on the other hand, the pressure value detected by the pressure sensor 22 could also be transferred from the pump electronic unit 17 to that in the operating unit 19 arranged control electronics unit 20 are transmitted to perform an evaluation in this. If the air pressure sensor 23 is not arranged in the operating unit 19, the air pressure value could also be transmitted from the pump electronic unit 17 to the operating electronic unit 20 in this case.
    A storage of detected pressure values and air pressure values can optionally take place in the pump electronics unit 17 or the control electronics unit 20.
    The initial adjustment of the pressure of the fluid in the hollow chamber to close the urethra can be performed as follows:
    By means of a catheter, water can be flowed through the urethra into the bladder from a vessel elevated at a defined height (e.g., 50 cm), whereby the pressure of the fluid in the hollow chamber 3 is increased until no more water flows through the ureter. Such a method is known as "leak point pressure measurement".
    The thus determined pressure value is stored as a reference value for the fluid pressure at which the body passage is closed. At the same time, the atmospheric pressure corresponding to the atmospheric pressure detected by the air pressure sensor 23 is stored as a reference value for the atmospheric pressure at which the reference value for the fluid pressure has been detected.
    Now, if the body passage has been closed by pressurizing the hollow chamber with this reference value for the fluid pressure and the atmospheric pressure changes while the volume of the fluid remains the same, the pressure value output by the pressure sensor 22 also changes by the same amount.
    Over time, for example, by osmosis or by a leak to a change in the volume of the fluid. By osmosis, the volume of fluid can also increase. Prior to a respective opening of the body channel is checked by the electronic control for this purpose, whether the atmospheric pressure and the fluid pressure have changed in the same way. If this is the case, the pressure value determined before opening the body channel is stored as a new reference value for the fluid pressure and the air pressure value detected before opening the body channel is stored as a new reference value for the atmospheric pressure. Upon re-closing the body passage, the fluid pressure is adjusted to the new reference value for the fluid pressure (i.e., the pressure prevailing prior to opening the body passage).
    Should it have come to a deviation, i. the detected values for the fluid pressure and the atmospheric pressure have not changed the same amount, the difference between the change of the atmospheric pressure and the change of the fluid pressure is detected. The new reference value for the fluid pressure is the sum of the pressure value ascertained before opening the body channel and the difference mentioned. The atmospheric pressure detected before opening the body passage is stored as a new reference value for the atmospheric pressure. When the body channel is closed again, the fluid pressure is adjusted to the new reference value for the fluid pressure.
    This process can be repeated each time the body canal is opened. However, it would also be possible to retain the stored reference values for a predetermined period of time and to perform the described check and, if necessary, correction only after this predefined time period during the next opening of the body channel.
    A respective opening (= release) of the body channel can be triggered by the user by a pressure on the operating element 21. A subsequent shut-off of the body passage can be done automatically after a certain time or triggered by the user, for example by renewed operation of the control element 21 or by pressing another control element. Various settings by the user may be enabled, e.g. an increase in the closing pressure of the fluid for a certain time.
    The inventive construction also allows other types of control of the medical device than those described above. Thus, a reference value for the fluid pressure and a reference value for the air pressure could be stored, and at each closing of the body passage, the reference value for the fluid pressure could be modified by the difference between the current measured value of the air pressure and the reference value of the air pressure. This procedure is particularly useful when starting from a constant volume of the fluid in the system. A measurement of the fluid pressure and the atmospheric pressure before opening the body passage could then be omitted or carried out for inspection.
    To fill the system with fluid, a port 25 is conventionally present. This can be connected for example via a hose to the pump part 11.
    Instead of an arrangement of the pressure sensor 22 in the fluid, it is also conceivable and possible to arrange the pressure sensor on a passage 24 bounding the surface 24 of the hinge part 1. It is measured by the pressure sensor so that directly applied to the body tissue pressure. Of course, this pressure depends on the pressure of the fluid in the hollow chamber 3 and is at least largely proportional to this. Deviations from the proportionality due to a non-linear behavior of the band member 1 at an enlargement of the hollow chamber 3 are preferably less than 10%.
    Depending on the nature of the drive 15, it may also be possible to deduce the magnitude of the fluid pressure from the current consumption of the drive 15. A pressure sensor for detecting the pressure of the fluid could be dispensed with.
    Key to the reference numbers: 1 band part 12 receiving space 1a inner section 13 bottom part 1b back section 14 control element 2 body tissue 15 drive 3 hollow chamber 16 gear 4 first closure member 17 pump electronics unit 4a insertion 18 battery 5 second closure member 19 control unit 5a tongue 20 control electronics unit 6 passage opening 21 Operating element 7 Longitudinal center axis 22 Pressure sensor 8 Connecting piece 23 Air pressure sensor 9 Hose 24 Surface 10 Pump unit 25 Port 11 Pump part 26 Housing
    权利要求:
    Claims (10)
    [1]
    claims
    1. A medical device for narrowing or shutting off a body passage, comprising - a band part (1) which can be placed around the body tissue surrounding the body channel (2) and to a passage opening (6) enclosing the body tissue can be closed, wherein the band part (1) has a hollow chamber (3) and wherein by introducing a fluid into the hollow chamber (3), the passage opening (6) is reduced in size, and - a pump unit (10) for conveying the fluid, which can be controlled by an electronic control of the device electric drive (15), wherein by the electronic control of the pressure of the fluid in the hollow chamber (3) corresponding to or dependent on this pressure value can be detected, characterized in that the device comprises an air pressure sensor (23) for detecting the atmospheric pressure.
    [2]
    2. Medical device according to claim 1, characterized in that the device comprises a pressure sensor (22) which is arranged in the fluid or adjacent to the fluid or to a passage opening (6) defining surface (24) of the band part (1).
    [3]
    3. Medical device according to claim 1 or 2, characterized in that the device comprises a spatially separated from the pump unit (10) arranged operating unit (19), wherein the pump unit (10) has a pump-electronics unit (17) and the operating unit (19 ) comprises a control electronics unit (20) and the electronic control of the device comprises the pump electronics unit (17) and the control electronics unit (20) and the pump electronics unit (17) and the control electronics unit (20) via a radio link communicate.
    [4]
    4. Medical device according to one of claims 1 to 3, characterized in that the pump unit (10) has a pump part (11) having a filled with the fluid receiving space (12) whose volume by means of the drive (15) is variable ,
    [5]
    5. Medical device according to claim 4, characterized in that the pump part (11) comprises a bellows.
    [6]
    6. Medical device according to claim 4 or 5, characterized in that the drive (15) an adjusting element (14) of the pump part (11) is adjustable, wherein in the adjustment of the adjusting element (14), the volume of the receiving space (12) of Pump part (11) changes.
    [7]
    7. Medical device according to one of claims 1 to 6, characterized in that the pump unit (10) has a battery (18) for supplying the drive (15) with electrical energy.
    [8]
    8. Medical device according to one of claims 1 to 7, characterized in that stored by the electronic control, a reference value of the pressure detected by the electronic control value and a reference value of the by means of the air pressure sensor (23) detected by the electronic control air pressure value, by means of the electronic control of the device is configured to adjust the pressure of the fluid in the hollow chamber (3) to contract or shut off the body passage in response to the stored reference value of the pressure value and the stored reference value of the air pressure value.
    [9]
    9. Medical device according to one of claims 1 to 8, characterized in that the medical device is an artificial Uretrasphinkter.
    [10]
    10. A method for operating a medical device for shutting off and releasing a body passage, comprising - a band part (1) which can be placed around the body tissue surrounding the body channel (2) and to a passage opening (6) enclosing the body tissue ring is closable , wherein the band part (1) has a hollow chamber (3) which can be filled with a fluid to reduce the passage opening (6), and - a pump unit (10) for conveying the fluid, which can be controlled by an electronic control of the device electrical Drive (15), wherein by the electronic control of the pressure of the fluid in the hollow chamber (3) corresponding to or dependent on this pressure value can be detected, characterized in that by the electronic control before the respective release of the body channel a current pressure value and means an air pressure sensor (23) a current air pressure value can be detected and the neuerli The pressure of the fluid in the hollow chamber (3) is adjusted by means of the electronic control as a function of the current pressure value and current air pressure value and in dependence on a stored reference value of the pressure value and a stored reference value of the air pressure value.
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    同族专利:
    公开号 | 公开日
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    AT518714B1|2018-09-15|
    US11197748B2|2021-12-14|
    WO2017205883A1|2017-12-07|
    CN109414314A|2019-03-01|
    BR112018074570A2|2019-03-12|
    US20190133737A1|2019-05-09|
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    US9375301B2|2013-06-06|2016-06-28|Coloplast A/S|Artificial urinary sphincter having a multi-compartment cuff|
    US9700396B2|2014-09-30|2017-07-11|Coloplast A/S|Urethra clamp|
    US10245133B2|2016-03-01|2019-04-02|University Of Dammam|Medical device for constricting a body passage and a method thereof|
    AT518764B1|2016-06-14|2018-03-15|Ami Agency Medical Innovations Gmbh|Medical device for shutting off a body canal|
    AT518411B1|2016-06-14|2017-10-15|Ami Agency Medical Innovations Gmbh|Medical device for shutting off a body canal|AT518764B1|2016-06-14|2018-03-15|Ami Agency Medical Innovations Gmbh|Medical device for shutting off a body canal|
    AT518411B1|2016-06-14|2017-10-15|Ami Agency Medical Innovations Gmbh|Medical device for shutting off a body canal|
    AT523786A1|2020-04-23|2021-11-15|Ami Agency Medical Innovations Gmbh|Method for setting a filling state of a liquid balloon|
    AT523787A1|2020-04-23|2021-11-15|Ami Agency Medical Innovations Gmbh|Device comprising a liquid balloon|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    ATA274/2016A|AT518714B1|2016-06-03|2016-06-03|Medical device for narrowing or shutting off a body canal|ATA274/2016A| AT518714B1|2016-06-03|2016-06-03|Medical device for narrowing or shutting off a body canal|
    PCT/AT2017/000042| WO2017205883A1|2016-06-03|2017-05-29|Medical device for narrowing or closing an anatomical channel|
    US16/097,700| US11197748B2|2016-06-03|2017-05-29|Medical device for narrowing or closing an anatomical channel|
    CN201780034387.4A| CN109414314B|2016-06-03|2017-05-29|Medical device for narrowing or intercepting a body passage|
    BR112018074570A| BR112018074570A2|2016-06-03|2017-05-29|medical equipment for narrowing or closing an anatomical canal and process for controlling the fluid volume of a medical equipment filled with fluid for closing or releasing an anatomical canal|
    EP17729750.4A| EP3463182A1|2016-06-03|2017-05-29|Medical device for narrowing or closing an anatomical channel|
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