• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The invention relates to an autoinjector comprising a base housing (2), a carpule (6), a needle arrangement (7), at least one drive assembly (8) and a safety assembly (9) which controls the drive assembly (8) until it is activated for the injection procedure Regarding the base housing (2) in its position. The securing assembly (9) comprises a securing cap (12) with a cap casing (14), a cap wall (15) and a securing pin (16) arranged inside the cap casing (14). Between the safety cap (12) and the base housing (2) there is provided a guide arrangement (17) with a first and a second guide element (19, 20) which fix an adjustment path (18) limited in the axial direction. The safety cap (12) is still arranged and held in the release position on the base housing (2).
    公开号:AT517801A1
    申请号:T50814/2015
    申请日:2015-09-24
    公开日:2017-04-15
    发明作者:
    申请人:Pharma Consult Gmbh；
    IPC主号:
    专利说明:

    The invention relates to an injection device, in particular an autoinjector for automated delivery of an injection liquid.
    US Pat. No. 6,767,336 B1 has disclosed an automated injection device for dispensing a medicament which comprises a support housing in which the drive assembly, the storage container for the medicament and the needle arrangement are arranged. Over the cannula of the needle assembly, an elastically deformable and pierceable protective element is slipped over, which is connected to the needle holder. The needle holder carries the needle on the one hand and is coupled to the storage container for the drug at its distal end. The cannula is always in fluid communication with the interior and thus with the drug. In the region of the distal end, a needle protection element is mounted longitudinally displaceably on the support housing, to which a further drive means is assigned. Starting from the proximal end of the support housing this is associated with a release sleeve or it takes the support housing at least partially. The first drive assembly is further associated with a cap-shaped securing element with a projecting into the injection device in locking pin to prevent accidental release. For unlocking, completely remove the cap together with the locking pin from the support housing. The triggering of the needle protection element or its drive means takes place during the relative displacement of the medicament storage together with the needle arrangement arranged thereon. Both the release sleeve and the needle protection element are arranged in close contact with each other and in the axial direction one behind the other on the common support housing. A disadvantage is that after removal of the safety cap an opening is visible both in the region of the distal end and in the region of the proximal end of the support housing.
    No. 4,031,893 A describes another similarly designed autoinjector in which the releasable drive assembly and the medicament container with the needle arrangement arranged thereon are accommodated in a common support housing. The drive assembly is in turn secured by a cap-shaped fuse element with a protruding into the injection device into the locking pin against unintentional release. The support housing is surrounded on its outer side by a sleeve-shaped component which is coupled at its proximal end with an additional release sleeve. The release sleeve causes after the complete removal of the fuse cap together with the locking pin, the triggering of the drive assembly, whereby the drug container is moved together with the needle assembly in the direction of the distal end. The cannula, which is always in fluid communication with the interior of the medicament container, is surrounded by an elastically deformable protective sheath which is supported on the inside of the distal end of the carrier housing. During forward movement, the cannula pierces the elastically deformable protective sheath and exits the carrier housing for injection. The elastically deformable needle protection cover causes after completion of the injection process a provision of the needle assembly together with the drug container in the interior of the support housing. Again, it is disadvantageous that after removal of the safety cap an opening is visible both in the region of the distal end and in the region of the proximal end of the support housing.
    From US 5,295,965 A an automated injection device for dispensing a medicament has become known in which the outer casing is a needle protection sleeve. This extends from the patient facing the distal end to near the proximal end and can be operated there with a cap-shaped release sleeve. For activation, a locking pin arranged in the area of the proximal end is to be released, which secures the first drive assembly until it is triggered by the cap-shaped release sleeve.
    After removal of the locking pin, the sleeve-shaped release sleeve can be moved relative to the support housing and the needle guard, whereby both the first drive assembly and the needle guard is triggered. The needle guard is in turn assigned its own spring device, with which this is adjusted in the position covering the needle. Again, it is disadvantageous that after removal of the locking pin both in the region of the distal end and in the region of the proximal end of the support housing, an opening is visible.
    From US 5,658,259 A and EP 0 956 058 B1 a further automated injection device for dispensing a medicament from a carpule has become known. For this purpose, the carpule is arranged with the drug within a support housing, which is additionally assigned to a first drive assembly for their operation and the delivery of the drug. Within the support housing a releasable by the longitudinal adjustment of the needle carrier needle protection sleeve is arranged, which is also associated with an adjustment. For release from the blocking division, a cover cap must first be removed in the region of the proximal end of the injection device, thereby allowing access to a securing pin. The locking pin is to be pressed in the direction of the distal end to actuate the first drive assembly. The needle guard is held within the support body by means of a latching connection until its release by the displaced needle carrier. After delivery of the drug, the needle guard covers the end of the needle projecting beyond the autoinjector. This injection device has a different trigger assembly and mode of action, since the injection device must first be placed on the desired puncture site and only subsequently the triggering of the first drive assembly by pushing in the locking pin.
    WO 2005/113039 A1 describes a differently designed autoinjector for dispensing a medicament, which comprises a stationary support housing with an inner and outer housing wall in the region of the distal end. In the support housing, the drive assembly, the storage container for the drug and the needle assembly is arranged. The proximal end of the needle is in fluid communication with the interior of the storage container and thus with the drug. Furthermore, the automatic injection device comprises a needle protection element displaceable in the direction of the longitudinal axis, which is mounted guided between the inner and outer housing wall of the support housing. This sleeve-shaped needle protection element is associated with a further drive assembly to spend this after release in the covering position of the needle. In addition, on the outside of the support housing, a handleability improving handle position may be arranged. At the opposite end of the needle - ie the proximal end - a triggering device for triggering the first drive assembly is arranged. The release movement takes place by a sliding movement in the vertical direction with respect to the longitudinal axis. After the transverse displacement and the unlocking of the restraint device, the first drive assembly is activated, whereby the piston displaced so far in the direction of the distal end, together with the storage container, until a stop of the storage container facing the proximal end comes into contact with a stop of the inner housing wall of the carrier housing. Simultaneously with this longitudinal adjustment is also the triggering of the needle protection element, which is thereby moved to the plant at the delivery point of the drug. After delivery of the drug and the removal of the entire injection device is due to the already activated further drive device further forward movement of the needle protection element until the needle is completely covered.
    The object of the present invention was to overcome the disadvantages of the prior art and to provide an injection device by means of which a user is able to make a simple and safe delivery of the medicament and thereby a wrong application direction and associated to avoid possible unwanted stab wounds.
    This object is achieved by an injection device according to the claims.
    The injection device according to the invention is designed to be adjustable from a storage position to an injection position and comprises a sleeve-shaped base housing, which base housing has a distal end facing a patient and a proximal end facing away therefrom, between which ends a longitudinal axis extends, a carpule with a therein and At least one drive assembly, which drive assembly includes a drive means for automatically dispensing the injection liquid to be dispensed in the injection process, a fuse assembly, which fuse assembly, the at least one drive assembly until its activation for the injection process with respect to the base housing in its position sets, the S a fuse cap having a cap skirt, a cap wall and arranged within the cap skirt and extending in the direction of the longitudinal axis locking pin, and wherein the fuse cap is held in the storage position on the base housing in a securing position for the at least one drive assembly, and the locking pin in the Fuse position holds at least one support arm of the fuse assembly in the radial direction with respect to the longitudinal axis fixed, and wherein the fuse cap is adjustable from its securing position in the axial direction in a release position, wherein the carpule, the needle assembly, the at least one drive assembly and the fuse assembly at least partially in the base housing are received or arranged, wherein between the fuse cap and the base housing a guide arrangement with at least a first guide element and with at least ei nem cooperating second guide element is provided, and that the at least one first guide element and the at least one second guide element define an axially limited adjustment of the safety cap between its securing position and its release position, whereby the safety cap is still arranged and held in its release position on the base housing, and thereby further from the locking pin, the at least one Flaltearm is released for the triggering of the drive assembly.
    The advantage achieved thereby is that such a possible misorientation of the injection device after unlocking the fuse assembly and the associated release for the injection process can be avoided. Since the otherwise removable held on the base housing fuse cap protrudes with its locking pin in a breakthrough of the base housing and thus keeps the Flaltearme positioned leaves after removing an open hole in the back wall of the base housing. Thus, it could happen that the user has not turned the intended distal end, from which the cannula emerges for the puncture process, the intended puncture site, but the wrong proximal end, from which the safety cap has been removed or removed. If it is also e.g. even the thumb or another body part placed on that end, which now faces the intended puncture site and from which the cannula emerges after triggering, the puncture and associated with the delivery of the injection liquid in this body part and not in the designated puncture site. Since now the fuse cap remains even after the adjustment in the release position on the base housing and can not be removed, such misalignments can be excluded. This possible misorientation occurs especially in situations where there is already an increased stress load for the user.
    Furthermore, it may be advantageous if the at least one first guide element is formed by an extension which is arranged or formed on an inner surface of the cap skirt and projects in the direction of the longitudinal axis. As a result, a safe adjustment of the safety cap on the base housing can be achieved. Furthermore, this also causes annoying
    Jumps are avoided on the fuse cap and a circumferentially closed design of the cap skirt can be achieved.
    Another embodiment is characterized in that the at least one second guide element is formed by a guideway, in particular recessed in the base housing, which is arranged or formed on the base housing in the region of the proximal end. By choosing the guideway, the longitudinal course and thus the adjustment of the safety cap can be determined. In addition, but also a clear axial length of the adjustment can be set so. This also in that case, when a pivoting or rotary movement of the safety cap is selected relative to the base housing.
    Another possible embodiment has the features that the guideway has in its longitudinal course with respect to a plane oriented in the direction perpendicular to the longitudinal axis a different pitch with mutually different pitch angles. As a result, depending on the selected pitch angle, the relative pivot or rotation angle of the safety cap can be set relative to the base housing.
    A further embodiment provides that the pitch angle of the guideway in the region of the securing position and / or the release position is formed flatter than in that between the securing position and the release position extending intermediate portion of the same. As a result, better axial positioning of the safety cap on the base housing can be achieved in the securing position and / or the release position.
    Another embodiment is characterized in that the at least one second guide element is formed by at least one in the region of the proximal end of the base housing or formed preferably circumferential groove-shaped recess and / or an extension. Thereby, a simple snap connection between the fuse cap and the base housing in at least one of the positions, namely the securing position and / or the release position, are created.
    A further preferred embodiment is characterized in that the fuse assembly further comprises a display unit, which display unit displays at least one of the two positions of the safety cap relative to the base housing. Thus, the user can be easily illustrated by means of the display unit, in which position the injection device, in particular their fuse assembly, is located.
    Furthermore, it may be advantageous if the display unit comprises at least a first display means, which is arranged or formed in the region of the safety cap. Thus, the fuse cap and its relative position with respect to the base housing can be clearly represented in a simple manner.
    Another alternative embodiment is characterized in that the at least one first display means is formed by an opening and / or a cap edge of the cap jacket arranged at a distance from the cap wall. This creates the possibility of being able to achieve a clear display and thus visualization of the operating state of the injection device even with a rotational or pivotal movement in addition to the axial adjustment.
    Another possible and optionally alternative embodiment has the features that the display unit comprises at least a second display means, which is preferably arranged or formed in the region of the base housing. Thus, in turn, the relative position and position of the safety cap in at least one relative position relative to the base housing can be easily displayed.
    A further embodiment provides that the display unit further comprises a display carrier element, which display carrier element is disposed within the cap skirt and immediately adjacent to the cap wall, and the display carrier element on the base housing is adjustably guided in the axial direction and further the safety cap is pivotable relative to the display carrier member about the longitudinal axis and further the display support member on the safety cap is held relatively positioned relative to it in the direction of the longitudinal axis. As a result, even in the area of the cap wall or end wall of the safety cap, a clear operating status indicator can always be created even with a relative pivoting or rotating movement of the safety cap relative to the base housing. Thus, the display support member can be adjusted only in the axial direction with respect to the base housing on this and still a pivoting or rotational movement of the fuse cap are performed both with respect to the display support member and the base housing.
    Another embodiment is characterized in that the display carrier element comprises a disk-shaped base body with an opening arranged in its center and at least one guide web projecting in the axial direction thereof. Thus, a simple recording of the display carrier element within the fuse cap is made possible while still achieving a secure axial guidance on the base housing.
    A further preferred embodiment is characterized in that the at least one guide web is arranged in the outer peripheral region of the disk-shaped base body. Thus, a recording between the cap jacket and the base housing can be achieved with minimal space requirements.
    Furthermore, it may be advantageous if a longitudinal guide arrangement is arranged or formed between the at least one guide web and the base housing. Thus, the entire display carrier element can be safely and rectilinearly guided on the base housing in the axial direction.
    Another embodiment is characterized in that the display unit comprises at least a first display means, which is formed as a breakthrough in the cap wall of the fuse cap. Thus, a simple optical visibility can be created on the injection device.
    Another possible embodiment has the features that the display unit comprises at least a second display means, which element on the Anzeigeeträgereie-, in particular on the disc-shaped base body of the display support member, is arranged. This creates the possibility of being able to carry out a simple change of the display of the display means. This can be done for example by simply replacing the display support element.
    A further embodiment provides that the at least one second display means is selected from the group of symbol, color code, marker ring, image, Braille, Braille. Thus, the respectively desired, optical representation can be selected for different application requirements.
    Another embodiment is characterized in that the securing assembly further comprises an actuating cap, which is releasably held on the safety cap. Thus, the possibility can be created for the user or user to continue to be able to remove a cap-like component from the injection device after adjusting the safety cap in the release position and still the fuse cap remains held on the base housing.
    Finally, a further preferred embodiment is characterized in that between the actuating cap and the safety cap, in particular in the region of the cap skirt, mutually engaging latching means are provided. This can be determined in a simple manner, the release force of the actuator cap of the fuse cap.
    For a better understanding of the invention, this will be explained in more detail with reference to the following figures.
    In each case, in a highly simplified, schematic representation:
    1 shows a possible embodiment of an injection device in its storage position, in perspective view;
    2 shows a possible embodiment of a guide arrangement on a safety cap for the injection device, in axial section;
    3 shows a possible embodiment of a base housing in the region of its proximal end, for a safety cap according to FIG. 2, in a view;
    Fig. 4 shows another possible embodiment of a fuse assembly of a
    Injection device, in perspective and distanced representation of the components;
    5 shows a further possible embodiment of the safety cap with an overlying, detachable actuating cap, in axial section;
    Fig. 6 shows other possible embodiments of the fuse assembly in still distanced representation of the components, partially cut.
    By way of introduction, it should be noted that in the differently described embodiments, the same parts are provided with the same reference numerals or the same component names, the disclosures contained in the entire description can be mutatis mutandis to the same parts with the same reference numerals or component names. Also, the location information chosen in the description, such as top, bottom, side, etc. related to the immediately described and illustrated figure and these position information in a change in position mutatis mutandis to transfer to the new location.
    The term "in particular" is understood below to mean that it may be a more specific training or specification of an object or a method step, but not necessarily a mandatory, preferred embodiment thereof or a procedure must be.
    FIGS. 1 to 6 each show an injection device 1 for dispensing a medicament or an injection liquid, the injection device 1 being designed for automated dispensing. In this case, the term auto-injector can be selected as the usual technical term. The individual embodiments in FIGS. 1 to 6 have only slight differences with respect to one another, although each of the embodiments may represent its own embodiment which is independent of itself, but individual detail designs of different embodiments may also be combined with one another.
    Thus, the most varied automated injection devices 1 are known, which are always designed to be automatically adjustable from a storage position into an injection position. In this case, both the puncture procedure and the dispensing process of the dispensed injection liquid or the drug takes place automatically and only after release and targeted triggering by the user.
    In order to avoid infection or transmission of diseases in the course of the puncture process and the associated dispensing process, at least those components penetrating into the body during the puncturing process are to be kept in a sterile condition during the storage position.
    In general, the injection device 1 comprises a plurality of individual components as well as assemblies formed therefrom. Thus, the injection device 1 may comprise a generally sleeve-shaped base housing 2 with a distal end 3 which can be turned towards the patient and a proximal end 4 facing away from the patient. Furthermore, can be used as a term for the location of front and back, with "front" the distal end 3 and "rear" is associated with the proximal end 4. Depending on the design of the injection device 1, the base housing 2 may also be referred to as a release sleeve or activation sleeve. This is the case in which the relative displacement of the base housing 2 in relation to the puncture site in a known manner, the triggering of the injection device 1 and the delivery of the fertile drug or the injection liquid is connected.
    As can now be seen from the schematically simplified representation of FIG. 1, a separate support housing 5 can be at least partially received or arranged within the base housing 2. Furthermore, the injection device 1 may also include a storage vessel, such as a carpule 6, a needle assembly 7, at least one drive assembly 8 and a fuse assembly 9. The needle assembly 7 comprises a cannula, which is provided at one end for insertion into the body and at the other end in fluid communication with the injection liquid in the carpule 6 before the injection process or in the course of the injection process with the interior of the carpule 6 in flow communication is brought.
    The receptacle for the injection liquid is formed here by the carpule 6, in which the medicament, the injection liquid or the drug to be dispensed and to be injected is already stored therein during the storage position and is ready to be dispensed. Thus, it is possible that the carpule 6, the needle assembly 7, the at least one drive assembly 8 and parts of the fuse assembly 9 are at least partially received in the base housing 2 or arranged thereon. If a separate support housing 5 is provided, the previously enumerated components can also be accommodated or arranged in this. The needle protection element 10 can be arranged in the radial direction between the support housing 5 and the base housing 2.
    The drive assembly 8 is operatively connected to the carpule 6 to at least perform the delivery of the drug or the injection liquid after a puncture. In order to prevent accidental puncture injuries after delivery and injection device 1 already removed from the body, the latter can also comprise a needle protection element 10 which securely covers at least the used cannula portion. For this purpose, a further releasable drive unit may be provided, which has not been shown for clarity. The needle protection element 10 together with its further drive unit can, but need not be provided.
    A longitudinal axis 11 extends between the distal end 3 and the proximal end 4 of the base housing 2. However, the longitudinal axis 11 can also be regarded as a common axis for the entire injection device 1.
    The needle assembly 7 is arranged upstream of the carpule 6 in the storage position and is located in the front region and thus in the region of the distal end 3.
    The drive assembly 8 comprises at least one drive means for the automatic delivery of the medicament to be delivered or the injection liquid, which drive means is usually formed by a compression spring. The drive means is secured by the fuse assembly 9 against release until a user deliberately activates the injection device 1, in which the drive assembly 8 is released and thus the injection device 1 is triggered. By the fuse assembly 9 thus the first drive assembly is set to their activation for the injection process with respect to the base housing 2 in position.
    It is possible that the base housing 2 may be formed in a split configuration. Thus, in the region of the distal end 3 of the injection device 1, the carpule 6, the needle assembly 7 and optionally also the needle protection element 10 together with its further drive unit can be arranged or accommodated. The drive assembly 8 and the fuse assembly 9 may be housed in that part of the base housing 2 which has or forms the proximal end 4. Thus, that part of the injection device 1, in which the medicament or the injection liquid is received, can be replaced with a fresh medicament or a fresh injection liquid after expiry of an expiry date for a new part. That part with the drive assembly 8 and the fuse assembly 9 can continue to be used.
    The essential part of the injection device 1 described here forms the securing assembly 9 for cooperation with the drive assembly 8.
    The fuse subassembly 9 determines the position of the at least one drive subassembly 8 until it is activated for the injection process with respect to the base housing 2. In the present exemplary embodiment, the securing assembly 9 comprises a securing cap 12 and at least one holding arm 13. The holding arm 13 forms the connecting member to the drive assembly 8 in a known manner. The holding arm or arms 13 is or are in a latched position in the region of the proximal end 4 on a holding disc held locked and held locked by a locking pin 16 until its release.
    The safety cap 12 in turn has a cap skirt 14 and a cap-pen wall 15. The cap casing 14 is preferably designed to run continuously over the circumference, wherein the cap wall 15 may also be referred to as end wall or top wall. Within the cap skirt 14, the locking pin 16 extending in the direction of the longitudinal axis 11 is arranged on the cap wall 15.
    The safety cap 12 is held or arranged in the storage position of the injection device 1 on the base housing 2 in a securing position for the at least one drive assembly 8. In this case, the securing pin 16 holds in the securing position at least one holding arm 13 of the securing assembly 9 in the radial direction with respect to the longitudinal axis 11 in a locked position fixed position. This is well known, only after the removal of the locking pin 16 from the region of the or the retaining arms 13 whose locked position are released by a corresponding activation process and thus the drive assembly 8 can be activated in a row.
    The safety cap 12 can be adjusted in the axial direction relative to the base housing 2, starting from its securing position into a release position, in which the locking pin 16 is disengaged from the or the retaining arms 13.
    In the hitherto known securing devices in such injection devices 1, the safety cap has been completely removed to release the drive assembly 8. This has become visible in the region of the proximal end 4 that the locking pin receiving opening, which could lead to incorrect operation. Since in each case an opening could be seen both in the region of the distal end 3 and in the region of the proximal end 4, it was not clear to some users which of the two ends was to be turned to the respective body site for the injection process.
    Thus, it is provided here that a separate guide arrangement 17 is provided or formed between the safety cap 12 and the base housing 2.
    Thus, a limited in the axial direction adjustment 18 of the fuse cap 12 between the securing position and the release position relative to the base housing 2 are set. By this limited displacement 18, the fuse cap 12 is still arranged or held in the release position on the base housing 2, but released from the locking pin 16 at least one Flaltearm 13 for the triggering of the drive assembly 8. The release position of the safety cap 12 is indicated in dash-dotted lines. Furthermore, a first guide element 19 and at least one second guide element 20 cooperating therewith are indicated in simplified fashion. The possible embodiments thereof are described in more detail below.
    As can now be better seen in FIGS. 2 and 3, the guide arrangement 17 may comprise at least a first guide element 19 and at least one second guide element 20 cooperating therewith. These two guide elements 19, 20 serve to set and limit the limited in the axial direction adjustment 18 between the fuse cap 12 and the base housing 2. Depending on the design of the guide elements 19, 20 but these can also be referred to as stops or extensions which define the respective position, namely the release position and / or the securing position in position relative to the base housing 2. In the present embodiment, the at least one guide element 19 is formed by an extension which is arranged or formed on an inner surface 21 of the cap skirt 14. In this case, the at least one, the first guide member 19 forming projection projects in the direction of the longitudinal axis 11 in the radial direction.
    The at least one second guide element 20 may be formed by a guideway 22 formed on or in the base housing 2. It is thus possible for the guideway 22 to be recessed or arranged on the outside of the base housing 2. Furthermore, the guide track 22 may be arranged or formed on the base housing in the region of the proximal end 4.
    The longitudinal course of the guideway 22 can be chosen or designed differently. As the simplest and shortest adjustment, for example, the guideway 22 extend only in the axial direction, whereby no relative rotational movement of the fuse cap 12 can take place during the adjustment of the base housing. This is shown and described in more detail in the following Fig. 6.
    However, it would also be possible for the guide track 22 to be inclined in the longitudinal direction with respect to a plane aligned in the direction perpendicular to the longitudinal axis 11. This can be covered by a rotational or pivotal movement of the fuse cap 12 about the longitudinal axis 11 of the base housing 2 also the axial displacement 18. The slope of the guideway 22 with respect to the aligned in the vertical direction to the longitudinal axis 11 plane may extend, for example, starting from the securing position towards the release position evenly inclined.
    However, it would also be possible, as can be seen in FIG. 3, for the guideway 22 to have a different pitch with mutually different pitch angles in the longitudinal direction of the plane aligned in the direction perpendicular to the longitudinal axis 11. Thus, the pitch angle of the guideway 22 in the securing position and / or the release position could be made shallower than in that between the securing position and the release position extending intermediate section. Thus, for example, in the region of the securing position and / or the release position, the pitch angle of the guide track 22 could run parallel with respect to that plane oriented in the direction perpendicular to the longitudinal axis 11.
    Furthermore, it is still possible that the fuse module 9 further comprises a display unit 23. By means of the display unit 23, it becomes possible to display at least one of the two positions of the safety cap 12 relative to the base housing 2 to the user. Thus, for example, the display unit 23 may comprise at least a first display means 24, which is arranged or formed in the region of the safety cap 12. In the simplest case, the first display means 24 could be formed, for example, by a cap edge of the cap skirt 14 arranged at a distance from the cap wall 15. A second display means 25 of the display unit 23 may preferably be arranged or formed in the region of the base housing 2.
    If, for example, the cap edge of the cap wall 15 is selected as the first indicator means 24, the second indicator 25, for example, can be formed by a mark distributed over the circumference of the base housing 2 or continuously formed. This marking can be formed for example by a colored ring, a groove or the like.
    However, it would also be possible that the at least one first display means 24 is formed by an opening or a window in the cap casing 14 and / or the cap wall 15, as will be shown and described below.
    Furthermore, it can be seen here that on the base housing 2, the second display means 25 is formed by a marking ring, in particular a groove-shaped recess 26. Thus, after the axial adjustment of the securing cap 12, the second indicating means 25 emerges about the adjustment path 18 extending in the axial direction below the cap edge of the cap casing 14, as illustrated in FIG. 3 by the securing cap 12 indicated by dashed and dotted lines. The axial displacement 18 is here by a rotary or. Pivoting movement about a pivoting angle by means of the cooperating first and second guide elements 19, 20 laid back.
    FIG. 4 shows a further embodiment of the injection device 1, which may be independent of itself, and in particular its fuse subassembly 9, with the same reference numerals or component designations being used again for the same parts as in the preceding FIGS. 1 to 3. To avoid unnecessary repetition, reference is made to the detailed description in the preceding Figs.
    The embodiment of the fuse subassembly 9 shown here is configured in a similar manner as previously described in detail in FIGS. 1 to 3. Therefore, only the formation of the fuse assembly 9 in the region of the proximal end 4 of the base housing 2 is discussed in more detail here.
    Again, in turn, the fuse cap 12 with the cap skirt 14, with the cap wall 15 and with the inside, but not shown
    Locking pin 16, available. The design of the guide assembly 17 is also the same as selected in FIGS. 2 and 3. The one or more guide elements 19 are in turn arranged on the inner surface 21 of the cap skirt 14, but these have not been shown in detail. The second guide elements 20 or 20 are each formed by their own guide tracks 22, wherein the longitudinal course in turn determines the axial displacement path 18, as has already been described above.
    The display unit 23 is differently designed here in contrast to the previously described embodiment. Thus, the display unit 23 comprises an additional display carrier element 27, which is arranged or received within the cap casing 14 and immediately adjacent to the cap wall 15 and thus within the safety cap 12 in the installed state. Furthermore, the display support member 27 is adjustably guided on the base housing 2 in the axial direction, so as to prevent or not permit a displacement or adjustment in the axial direction, but a rotation or pivoting about the longitudinal axis 11.
    The safety cap 12 is in turn pivotable relative to the display support member 27 about the longitudinal axis 11 or rotatable. The extent of the Verschwend or angle of rotation of the fuse cap 12 relative to the base housing 2 is defined or fixed by the guide assembly 17, in particular the circumferential extent of the guideway 22. Further, the display support member 27 is held on the safety cap 12 relatively positioned with respect thereto in the direction of the longitudinal axis 11. This can be done by unspecified retaining lugs or a groove-shaped recess, which is arranged in the inner surface 21 of the cap skirt 14. Thus, the display support member 27 together with the safety cap 12 perform the adjustment along the axial displacement path 18 together with, however, a relative pivoting or rotation of the display support member 27 about the longitudinal axis 11 of the base housing 2 is prevented.
    Thus, in this embodiment, the display support member 27 comprises a disc-shaped base body 28 having an opening 29 disposed in the center thereof. The opening 29 serves to receive or pass the securing pin 16 arranged in the safety cap 12. Furthermore, the display support element 27 comprises at least one In this case, the at least one guide web 30 may be arranged in the outer peripheral region of the disk-shaped base body 28 extending in the axial direction thereof or projecting therefrom guide web. Preferably, two such guide webs 30 are provided to ensure proper axial guidance of the display support member 27 on the base housing 2. The two guide webs 30 are arranged in a mutually diametrically opposed arrangement on the disk-shaped base body 28. For receiving the guide webs 30 or flats formed opposite the base housing 2 are provided in order to be able to receive the two guide webs 30 within the safety cap 12.
    In addition, between the at least one guide web 30 and the base housing 2, a longitudinal guide arrangement 31 may be arranged or formed. The longitudinal guide assembly 31 may comprise cooperating longitudinal guide members which are not further specified. These can be formed, for example, by a groove-shaped depression and a web or the like engaging in it.
    The display unit is formed in this embodiment shown here by at least a first display means 24 which is formed as a breakthrough in the cap wall 15 of the fuse cap 12. In the present embodiment, two openings are provided, these two openings are arranged diametrically opposite each other in the cap wall 15.
    The display unit 23 further comprises here the at least second display means 25, which is arranged or formed on the display carrier element 27, in particular on the disc-shaped base body 28. In this case, that or the second display means 25 are arranged on that side of the display support member 27, which is the cap wall 15 and the or arranged in this apertures facing.
    The at least one second display means 25 may be formed and / or selected from the group of symbols, color code, marker ring, image, groove-shaped depression, Braille, Braille.
    In the symbols or images, for example, an open or closed lock, different colors or the like could be selected. This is to be clearly signaled to the user clearly that in the backup position befindlicher fuse cap, the injection device 1 is still in its storage position and thus a release or actuation of the drive assembly 8 is not possible. Only after carried out adjustment of the safety cap 12 in the axial direction in the corresponding release position to the user by the appearance or appearance of the second display means 25 clearly signaled that the injection device 1 for the activation of the drive assembly 8 and the associated delivery of the drug or the Injection liquid is ready.
    FIG. 5 shows a further embodiment of the injection device 1, which may be independent of itself, and in particular its fuse subassembly 9, with the same reference numerals or component designations being used again for the same parts as in the preceding FIGS. 1 to 4. To avoid unnecessary repetition, reference is made to the detailed description in the preceding Figs. 1 to 4 or reference.
    Since in all the embodiments shown and described here in principle the fuse cap 12 is also arranged and held in the release position on the base housing 2, the possibility is created for the user that nevertheless a cap-like part for the release of the injection device 1 removed from the base housing 2 can be. For this purpose, it is provided that the fuse assembly 9 further comprises an actuating cap 32 which is releasably held on the safety cap 12. The actuation cap 32 engages over the safety cap 12 in the region of its cap skirt 14 and can in particular completely absorb it. Furthermore, between the actuating cap 32 and the safety cap 12, in particular in the region of
    Cap jacket 14 of the same, mutually engaging locking means 33 may be provided.
    It would thus be possible to provide at least one latching extension 35 arranged on a spring arm 34 on the safety cap 12 as latching means 33. As a further latching means 33, at least one latching recess 35 receiving the latching recess 35 can be arranged or provided on the actuating cap 32, in particular its cap casing.
    Since the at least one latching projection 35 is arranged on a spring arm 34, it becomes possible for a user, after overcoming the latching force, to bring the actuating cap 32 out of engagement with the latching projection or projections 35 of the safety cap 12 and thus remove the actuating cap 32 from the safety cap 12 to be able to.
    FIG. 6 shows two further and optionally independent embodiments of the injection device 1, in particular their fuse assemblies 9, with the same reference numerals or component designations being used again for the same parts as in the preceding FIGS. 1 to 5. To avoid unnecessary repetition, reference is made to the detailed description in the preceding Figs. 1 to 5 or reference.
    As already briefly described above, further possible arrangements and configurations of guide arrangements 17 for defining or defining the axial adjustment path 18 are shown here.
    In dotted lines that embodiment is shown in which only a pure straight, axial adjustment between the fuse cap 12 and the base housing 2 is possible. The first guide element 19 is in turn arranged on the inner surface 21 of the cap skirt 14. The longitudinal course of the second guide member 20 forming guideway 22 is formed as a groove-shaped depression, but with a pure axial extension, on the base housing 2.
    In the embodiment shown in solid lines, in the region of the open end of the cap skirt 14, in particular in the region of its cap edge, the first guide element or elements 19 are formed as individual projections.
    But it would also be possible to form the first guide member 19 by a circumferential, in the direction of the longitudinal axis 11 projecting collar or flange approach.
    The second guide element 20 is preferably formed in two versions on the base housing 2 as a groove-shaped depression. The axial distance corresponds to the intended axial displacement path 18. Thus, both in the securing position of the safety cap 12 and in its release position, a positioned mounting of the safety cap 12 in the region of the proximal end 4 of the base housing 2 is achieved. But it would also be possible to provide only one of the two groove-shaped recesses shown as a second guide member 20.
    Again, in this embodiment, the display unit 23 may be provided with at least a first display means 24 and at least one second display means 25. The training can be carried out analogously, as has already been described above. Since there is preferably no circumferential, relative adjustment between the base housing 2 and the safety cap 12, the embodiment of the display unit 23 can be selected, as has been described in particular in FIG.
    If a guide track 22 is selected as the second guide element 20, this could also be designed such that, starting from the securing position, a pivoting or rotational movement is made possible both in the clockwise direction and against it. If one of the two possible rotation senses has been selected and the safety cap 12 has been moved into the release position, the adjustment path 18 which is limited in the axial direction is covered.
    In addition or independently of all the above-described embodiments could also be provided that upon reaching the release position, an additional locking between the guide elements 19, 20 is achieved. For this purpose, in the guideway 22 a projection not shown in detail or
    Approach and / or a recess for receiving the first guide member 19 may be provided.
    Another application variant should also be possible, in which the safety cap 12 can be adjusted from the release position back to the backup position even before the activation of the drive assembly 8. This allows a user that with not yet triggered drive assembly 8, the storage position of the injection device 1 can be restored.
    The outer cross-section of the cap skirt 14 can also be provided with flattenings and / or extensions and / or can also have a polygonal outer cross-section in order to prevent the injection device 1 from rolling away.
    The embodiments show possible embodiments, it being noted at this point that the invention is not limited to the specifically illustrated embodiments thereof, but also various combinations of the individual embodiments are mutually possible and this variation possibility due to the teaching of technical action by representational invention in Can the expert working in this technical field.
    The scope of protection is determined by the claims. However, the description and drawings are to be considered to interpret the claims. Individual features or combinations of features from the illustrated and described different embodiments may represent for themselves inventive solutions. The task underlying the independent inventive solutions can be taken from the description. All statements of value ranges in the present description should be understood to include any and all sub-ranges thereof, e.g. is the statement 1 to 10 to be understood that all sub-areas, starting from the lower limit 1 and the upper limit 10 are included, ie. all subareas begin with a lower limit of 1 or greater and end at an upper limit of 10 or less, e.g. 1 to 1.7, or 3.2 to 8.1, or 5.5 to 10.
    For the sake of order, it should finally be pointed out that for a better understanding of the construction, elements have been shown partially unevenly and / or enlarged and / or reduced in size.
    LIST OF REFERENCES 1 injection device 31 longitudinal guide arrangement 2 base housing 32 actuating cap 3 end 33 locking means 4 end 34 spring arm 5 support housing 35 latching projection 6 carpule 36 latching recess 7 needle assembly 8 drive assembly 9 fuse assembly 10 needle protection element 11 longitudinal axis 12 securing cap 13 retaining arm 14 cap casing 15 cap wall 16 locking pin 17 guide assembly 18 adjustment 19 first guide element 20 second guide element 21 inner surface 22 guide track 23 display unit 24 first display means 25 second display means 26 recess 27 display carrier element 28 base body 29 opening 30 guide bar
    权利要求:
    Claims (19)
    [1]
    claims
    1. injection device (1), in particular autoinjector for dispensing an injection liquid, wherein the injection device (1) is adjustable from a storage position into an injection position, with a sleeve-shaped base housing (2), which base housing (2) zuwendbares a patient distal end (3) and a proximal end (4) averted therefrom, between which ends (3, 4) a longitudinal axis (11) extends, a carpule (6) with the injection liquid contained therein and to be dispensed during the injection process, a needle arrangement (7) in front of the carpule (6) in the storage position of the injection device (1) in the section of the distal end (3) of at least one drive assembly (8), which drive assembly (8) comprises a drive means for automatically dispensing the injection liquid to be dispensed during the injection process Fuse assembly (9), which fuse assembly (9) zumin at least one drive assembly (8) until its activation for the injection process with respect to the base housing (2) determines its position, wherein the fuse assembly (9) has a safety cap (12) with a cap jacket (14), a cap wall (15) and an inside the locking cap (16) arranged in the storage position on the base housing (2) is held in a securing position for the at least one drive assembly (8) , and the securing pin (16) in the securing position at least one holding arm (13) of the securing assembly (9) in the radial direction with respect to the longitudinal axis (11) keeps stationary, and wherein the safety cap (12) starting from its securing position in the axial direction in a release position is adjustable, wherein the carpule (6), the needle assembly (7), the at least one Antriebsbau group (8) and the Fuse assembly (9) at least partially in the base housing (2) are received or arranged, characterized in that between the fuse cap (12) and the base housing (2) has a guide assembly (17) with at least a first guide element (19) and at least one cooperating second guide element (16) is provided, and that the at least one first guide element (19) and the at least one second guide element (20) define an axially limited adjustment path (18) of the safety cap (12) between its securing position and its release position, whereby the Locking cap (12) in its release position is still arranged and held on the base housing (2), and further from the locking pin (16) the at least one holding arm (13) is released for the triggering of the drive assembly (8).
    [2]
    2. Injection device (1) according to claim 1, characterized in that the at least one first guide element (19) is formed by an extension which is arranged or formed on an inner surface (21) of the cap skirt (14) and this in the direction of the Longitudinal axis (11) protrudes.
    [3]
    3. Injection device (1) according to claim 1 or 2, characterized in that the at least one second guide element (20) by a recessed in particular in the base housing (2) formed guideway (22) is formed, which on the base housing (2) in the region of proximal end (4) is arranged or formed.
    [4]
    4. Injection device (1) according to claim 3, characterized in that the guide track (22) in the longitudinal direction with respect to a direction perpendicular to the longitudinal axis (11) aligned plane has a different pitch with mutually different pitch angles.
    [5]
    5. Injection device (1) according to claim 3 or 4, characterized in that the pitch angle of the guide track (22) in the securing position and / or the release position is formed shallower than in that between the securing position and the release position extending intermediate portion thereof.
    [6]
    6. Injection device (1) according to claim 1 or 2, characterized in that the at least one second guide element (20) by at least one in the region of the proximal end (4) of the base housing (2) arranged or formed preferably circumferential groove-shaped recess and / or an extension is formed.
    [7]
    7. Injection device (1) according to one of the preceding claims, characterized in that the securing assembly (9) further comprises a display unit (23), which display unit (23) at least one of the two positions of the safety cap (12) relative to the base housing (2 ).
    [8]
    8. Injection device (1) according to claim 7, characterized in that the display unit (23) comprises at least a first display means (24) which is arranged or formed in the region of the safety cap (12).
    [9]
    9. Injection device (1) according to claim 8, characterized in that the at least one first indicating means (24) is formed by an opening and / or a cap edge of the cap skirt (14) arranged at a distance from the cap wall (15).
    [10]
    10. Injection device (1) according to one of claims 7 to 9, characterized in that the display unit (23) comprises at least a second display means (25), which is preferably arranged or formed in the region of the base housing (2).
    [11]
    11. Injection device (1) according to claim 7, characterized in that the display unit (23) further comprises a display carrier element (27), which display carrier element (27) within the cap skirt (14) and immediately adjacent to the cap wall (15) is arranged, and the display support element (27) is adjustably guided in the axial direction on the base housing (2) and furthermore the safety cap (12) is pivotable relative to the display support element (27) about the longitudinal axis (11) and further the display support element (27) on the safety cap (12) held relatively positioned relative to this in the direction of the longitudinal axis (11).
    [12]
    12. Injection device (1) according to claim 11, characterized in that the display carrier element (27) comprises a disk-shaped base body (28) with an opening arranged in its center (29) and at least one in the axial direction thereof projecting guide web (30).
    [13]
    13. Injection device (1) according to claim 12, characterized in that the at least one guide web (30) in the outer peripheral region of the disk-shaped base body (28) is arranged.
    [14]
    14. Injection device (1) according to claim 12 or 13, characterized in that between the at least one guide web (30) and the base housing (2) a longitudinal guide arrangement (31) is arranged or formed.
    [15]
    15. Injection device (1) according to any one of claims 7 or 11 to 14, characterized in that the display unit (23) comprises at least a first display means (24) which is formed as an opening in the cap wall (15) of the safety cap (12) ,
    [16]
    16. Injection device (1) according to any one of claims 11 to 15, characterized in that the display unit (23) comprises at least a second display means (25) which on the display support member (27), in particular on the discs shaped base body (28) of the display support member (27) is arranged.
    [17]
    17. Injection device (1) according to claim 10 or 16, characterized in that the at least one second display means (25) from the group of symbol, color code, marking ring, groove-shaped depression (26), image, Braille, Braille is selected.
    [18]
    18. Injection device (1) according to any one of the preceding claims, characterized in that the securing assembly (9) further comprises an actuating cap (32) which is releasably held on the safety cap (12).
    [19]
    19. Injection device (1) according to claim 18, characterized in that between the actuating cap (32) and the safety cap (12), in particular in the region of the cap jacket (14), mutually engaging latching means (33) are provided.
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    同族专利:
    公开号 | 公开日
    PT3352817T|2021-06-29|
    AT517801B1|2017-09-15|
    US10744263B2|2020-08-18|
    US20180296760A1|2018-10-18|
    WO2017050919A1|2017-03-30|
    EP3352817A1|2018-08-01|
    EP3352817B1|2021-03-24|
    DK3352817T3|2021-06-28|
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    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    ATA50814/2015A|AT517801B1|2015-09-24|2015-09-24|Injection device, in particular autoinjector|ATA50814/2015A| AT517801B1|2015-09-24|2015-09-24|Injection device, in particular autoinjector|
    PCT/EP2016/072585| WO2017050919A1|2015-09-24|2016-09-22|Injection device, in particular an auto-injector|
    US15/762,832| US10744263B2|2015-09-24|2016-09-22|Injection device, in particular an auto-injector|
    DK16774472.1T| DK3352817T3|2015-09-24|2016-09-22|Injection device, especially as an auto-injector|
    EP16774472.1A| EP3352817B1|2015-09-24|2016-09-22|Injection device, in particular an auto-injector|
    PT167744721T| PT3352817T|2015-09-24|2016-09-22|Injection device, in particular an auto-injector|
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